Showing entry for ATP-binding cassette sub-family C member 8


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT013036
Protein NameATP-binding cassette sub-family C member 8
Uniport IdQ09428
GeneABCC8
Gene Id6833
DomainABC_membrane; ABC_tran
Pfam PF00664   PF00005  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.1 Membrane transport hsa02010 ABC transporters
5. Organismal Systems 5.2 Endocrine system hsa04911 Insulin secretion
6. Human Diseases 6.7 Endocrine and metabolic diseases hsa04930 Type II diabetes mellitus
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0098662 inorganic cation transmembrane transport
Biological Process GO:0071805 potassium ion transmembrane transport
Biological Process GO:0006813 potassium ion transport
Biological Process GO:0050796 regulation of insulin secretion
Biological Process GO:0055085 transmembrane transport
molecular function GO:0016887 ATPase activity
molecular function GO:0019829 ATPase-coupled cation transmembrane transporter activity
molecular function GO:0042626 ATPase-coupled transmembrane transporter activity
molecular function GO:0005524 ATP binding
molecular function GO:0044325 ion channel binding
molecular function GO:0005267 potassium channel activity
molecular function GO:0008281 sulfonylurea receptor activity
cellular component GO:0008282 inward rectifying potassium channel
cellular component GO:0016020 membrane
cellular component GO:0005886 plasma membrane
cellular component GO:0031004 potassium ion-transporting ATPase complex
Reactome
Pathway Id Pathway Name
R-HSA-112316 Neuronal System
R-HSA-1296025 ATP sensitive Potassium channels
R-HSA-1296065 Inwardly rectifying K+ channels
R-HSA-1296071 Potassium Channels
R-HSA-1430728 Metabolism
R-HSA-163685 Integration of energy metabolism
R-HSA-1643685 Disease
R-HSA-422356 Regulation of insulin secretion
R-HSA-5619084 ABC transporter disorders
R-HSA-5619115 Disorders of transmembrane transporters
R-HSA-5683177 Defective ABCC8 can cause hypo- and hyper-glycemias
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001430 BXGD000054 Adenoma Neoplasms
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002736 BXGD000127 Amyotrophic Lateral Sclerosis Nutritional and Metabolic Diseases; Nervous System Diseases
C0003635 BXGD000214 Apraxias Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0003811 BXGD000222 Cardiac Arrhythmia Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0003868 BXGD000233 Arthritis, Gouty Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0003872 BXGD000235 Arthritis, Psoriatic Skin and Connective Tissue Diseases; Musculoskeletal Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0003886 BXGD000238 Arthrogryposis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0004134 BXGD000256 Ataxia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0004903 BXGD000293 Beckwith-Wiedemann Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0005745 BXGD000331 Blepharoptosis Eye Diseases
C0005890 BXGD000345 Body Height
C0006118 BXGD000372 Brain Neoplasms Neoplasms; Nervous System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0007785 BXGD000485 Cerebral Infarction Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009404 BXGD000606 Colorectal Neoplasms Digestive System Diseases; Neoplasms
C0009421 BXGD000608 Comatose Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0010034 BXGD000640 Corneal Diseases Eye Diseases
C0010054 BXGD000647 Coronary Arteriosclerosis Cardiovascular Diseases
C0010674 BXGD000683 Cystic Fibrosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Respiratory Tract Diseases
C0011175 BXGD000701 Dehydration Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011880 BXGD000759 Diabetic Ketoacidosis Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011881 BXGD000760 Diabetic Nephropathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0011991 BXGD000766 Diarrhea Pathological Conditions, Signs and Symptoms
C0013144 BXGD000800 Drowsiness Mental Disorders
C0014070 BXGD000887 Encephalomyelitis Infections; Nervous System Diseases
C0014474 BXGD000917 Ependymoma Neoplasms
C0014859 BXGD000961 Esophageal Neoplasms Digestive System Diseases; Neoplasms
C0015544 BXGD001003 Failure to Thrive Pathological Conditions, Signs and Symptoms
C0015934 BXGD001026 Fetal Growth Retardation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017979 BXGD001159 Glycosuria Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0018099 BXGD001172 Gout Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0018790 BXGD001221 Cardiac Arrest Cardiovascular Diseases
C0018798 BXGD001223 Congenital Heart Defects Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0018817 BXGD001235 Atrial Septal Defects Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0019209 BXGD001305 Hepatomegaly Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0020224 BXGD001366 Polyhydramnios Female Urogenital Diseases and Pregnancy Complications
C0020456 BXGD001392 Hyperglycemia Nutritional and Metabolic Diseases
C0020458 BXGD001393 Hyperhidrosis disorder Skin and Connective Tissue Diseases
C0020459 BXGD001394 Hyperinsulinism Nutritional and Metabolic Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0020555 BXGD001431 Hypertrichosis Skin and Connective Tissue Diseases
C0020557 BXGD001432 Hypertriglyceridemia Nutritional and Metabolic Diseases
C0020615 BXGD001445 Hypoglycemia Nutritional and Metabolic Diseases
C0020617 BXGD001446 Hypoglycemic coma Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases; Nervous System Diseases; Endocrine System Diseases
C0021290 BXGD001491 Neonatal disorder Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0021655 BXGD001508 Insulin Resistance Nutritional and Metabolic Diseases
C0021670 BXGD001509 insulinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0022107 BXGD001530 Irritable Mood Behavior and Behavior Mechanisms
C0022568 BXGD001552 Keratitis Eye Diseases
C0022638 BXGD001567 Ketosis Nutritional and Metabolic Diseases
C0022658 BXGD001570 Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023380 BXGD001640 Lethargy Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0023418 BXGD001642 leukemia Neoplasms
C0023434 BXGD001643 Chronic Lymphocytic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023448 BXGD001649 Lymphoid leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023449 BXGD001650 Acute lymphocytic leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023487 BXGD001669 Acute Promyelocytic Leukemia Neoplasms
C0023530 BXGD001683 Leukopenia Hemic and Lymphatic Diseases
C0023646 BXGD001690 Lichen Planus Skin and Connective Tissue Diseases
C0023976 BXGD001724 Long QT Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0024143 BXGD001741 Lupus Nephritis Female Urogenital Diseases and Pregnancy Complications; Skin and Connective Tissue Diseases; Male Urogenital Diseases; Immune System Diseases
C0024198 BXGD001743 Lyme Disease Infections
C0025149 BXGD001826 Medulloblastoma Neoplasms
C0025202 BXGD001832 melanoma Neoplasms
C0025295 BXGD001855 Meningitis, Pneumococcal Infections; Nervous System Diseases
C0025517 BXGD001875 Metabolic Diseases Nutritional and Metabolic Diseases
C0025958 BXGD001882 Microcephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0026691 BXGD001917 Mucocutaneous Lymph Node Syndrome Skin and Connective Tissue Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0026827 BXGD001936 Muscle hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0026838 BXGD001938 Muscle Spasticity Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027121 BXGD001973 Myositis Musculoskeletal Diseases; Nervous System Diseases
C0027540 BXGD001996 Necrosis Pathological Conditions, Signs and Symptoms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027765 BXGD002033 nervous system disorder Nervous System Diseases
C0027773 BXGD002035 Nesidioblastosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Nutritional and Metabolic Diseases
C0027796 BXGD002037 Neuralgia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0030232 BXGD002197 Pallor Pathological Conditions, Signs and Symptoms
C0030354 BXGD002214 Papilloma Neoplasms
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0030805 BXGD002256 Bullous pemphigoid Skin and Connective Tissue Diseases; Immune System Diseases
C0031099 BXGD002282 Periodontitis Stomatognathic Diseases
C0033377 BXGD002406 Ptosis Pathological Conditions, Signs and Symptoms
C0035309 BXGD002530 Retinal Diseases Eye Diseases
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0036857 BXGD002638 Severe intellectual disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0038220 BXGD002740 Status Epilepticus Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0038238 BXGD002741 Steatorrhea Digestive System Diseases; Nutritional and Metabolic Diseases
C0038379 BXGD002752 Strabismus Eye Diseases; Nervous System Diseases
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0038525 BXGD002768 Subarachnoid Hemorrhage Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0039231 BXGD002799 Tachycardia Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0039263 BXGD002805 Takayasu Arteritis Skin and Connective Tissue Diseases; Cardiovascular Diseases
C0040156 BXGD002849 Thyrotoxicosis Endocrine System Diseases
C0042384 BXGD002979 Vasculitis Cardiovascular Diseases
C0042842 BXGD003005 Vitamin A Deficiency Nutritional and Metabolic Diseases
C0042963 BXGD003018 Vomiting Pathological Conditions, Signs and Symptoms
C0043528 BXGD003050 Zoonoses Infections; Animal Diseases
C0079293 BXGD003069 Epidermolysis Bullosa Acquisita Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0085207 BXGD003140 Gestational Diabetes Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0085413 BXGD003171 Polycystic Kidney, Autosomal Dominant Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0085631 BXGD003214 Agitation Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0149940 BXGD003391 Sciatic Neuropathy Nervous System Diseases
C0151744 BXGD003469 Myocardial Ischemia Cardiovascular Diseases
C0151747 BXGD003471 Renal tubular disorder Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0151779 BXGD003473 Cutaneous Melanoma Neoplasms; Skin and Connective Tissue Diseases
C0151786 BXGD003475 Muscle Weakness Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0151889 BXGD003498 Hyperreflexia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0152421 BXGD003586 Macrotia
C0154830 BXGD003746 Proliferative diabetic retinopathy Pathological Conditions, Signs and Symptoms; Eye Diseases; Endocrine System Diseases; Cardiovascular Diseases
C0158981 BXGD003914 Neonatal diabetes mellitus Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Endocrine System Diseases
C0158986 BXGD003916 Neonatal hypoglycemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0162275 BXGD003924 Ketonuria Nutritional and Metabolic Diseases
C0162871 BXGD003996 Aortic Aneurysm, Abdominal Cardiovascular Diseases
C0178664 BXGD004032 Glomerulosclerosis (disorder) Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Cardiovascular Diseases
C0205682 BXGD004105 Waist-Hip Ratio
C0205734 BXGD004115 Diabetes, Autoimmune Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0206624 BXGD004190 Hepatoblastoma Neoplasms
C0206669 BXGD004229 Hepatocellular Adenoma Digestive System Diseases; Neoplasms
C0220994 BXGD004357 Hyperammonemia Pathological Conditions, Signs and Symptoms
C0232180 BXGD004533 Cardiac shunt
C0232466 BXGD004543 Feeding difficulties
C0235991 BXGD004802 Small for gestational age (disorder) Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0242381 BXGD005159 Lyme Arthritis Infections
C0242422 BXGD005163 Parkinsonian Disorders Nervous System Diseases
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0263666 BXGD005341 Dermatomyositis, Childhood Type Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Nervous System Diseases
C0265610 BXGD005555 Clinodactyly of fingers Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0266267 BXGD005638 Congenital hypoplasia of pancreas Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0266589 BXGD005698 Congenital ear anomaly NOS (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Otorhinolaryngologic Diseases
C0266929 BXGD005722 Chronic Periodontitis Stomatognathic Diseases
C0267963 BXGD005796 Exocrine pancreatic insufficiency Digestive System Diseases
C0268446 BXGD005949 Thyrotoxic periodic paralysis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases; Nervous System Diseases
C0268800 BXGD006041 Simple renal cyst Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0270824 BXGD006113 Visual seizure Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0271650 BXGD006227 Impaired glucose tolerance Nutritional and Metabolic Diseases
C0271703 BXGD006242 Factitious hypoglycemia Nutritional and Metabolic Diseases; Mental Disorders
C0271708 BXGD006244 Fasting Hypoglycemia Nutritional and Metabolic Diseases
C0271714 BXGD006248 Hypoglycemia, leucine-induced Nutritional and Metabolic Diseases
C0278510 BXGD006526 Childhood Medulloblastoma Neoplasms
C0278650 BXGD006553 Childhood Supratentorial Ependymoma Neoplasms
C0278874 BXGD006605 Adult Ependymoma Neoplasms
C0278876 BXGD006607 Adult Medulloblastoma Neoplasms
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0302511 BXGD006849 Small for gestational age fetus Pathological Conditions, Signs and Symptoms
C0332890 BXGD006909 Congenital hemihypertrophy Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0333516 BXGD006957 Tumor necrosis Pathological Conditions, Signs and Symptoms
C0333559 BXGD006960 Infarction, Lacunar Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0342257 BXGD007447 Complications of Diabetes Mellitus Endocrine System Diseases
C0342273 BXGD007448 Transient neonatal diabetes mellitus
C0342276 BXGD007449 Maturity onset diabetes mellitus in young Nutritional and Metabolic Diseases; Endocrine System Diseases
C0342277 BXGD007450 Diabetes mellitus autosomal dominant type II (disorder) Nutritional and Metabolic Diseases; Endocrine System Diseases
C0342302 BXGD007458 Brittle diabetes Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0349588 BXGD007933 Short stature
C0376618 BXGD008003 Endotoxemia Pathological Conditions, Signs and Symptoms; Infections
C0424295 BXGD008524 Hyperactive behavior Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0424605 BXGD008535 Developmental delay (disorder) Mental Disorders
C0431663 BXGD008700 Bilateral Cryptorchidism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Male Urogenital Diseases; Endocrine System Diseases
C0432217 BXGD008740 Wolcott-Rallison syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases; Immune System Diseases; Endocrine System Diseases
C0456070 BXGD008863 Growth delay
C0494475 BXGD009030 Tonic - clonic seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0497406 BXGD009064 Overweight Pathological Conditions, Signs and Symptoms
C0519030 BXGD009078 Pneumonia due to Klebsiella pneumoniae Infections; Respiratory Tract Diseases
C0520679 BXGD009101 Sleep Apnea, Obstructive Respiratory Tract Diseases; Nervous System Diseases
C0520947 BXGD009126 Clumsiness - motor delay Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0524620 BXGD009236 Metabolic Syndrome X Nutritional and Metabolic Diseases
C0546884 BXGD009345 Hypovolemia Pathological Conditions, Signs and Symptoms
C0555278 BXGD009436 Cerebral metastasis
C0557874 BXGD009444 Global developmental delay
C0597167 BXGD009652 Islets of Langerhans hyperplasia Pathological Conditions, Signs and Symptoms
C0598766 BXGD009669 Leukemogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0600228 BXGD009699 Cardiopulmonary Arrest Cardiovascular Diseases
C0677607 BXGD009721 Hashimoto Disease Endocrine System Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0684276 BXGD009793 Hypsarrhythmia Nervous System Diseases
C0730345 BXGD009960 Microalbuminuria Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0740392 BXGD009988 Infarction, Middle Cerebral Artery Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0742343 BXGD010061 Acute Chest Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases; Hemic and Lymphatic Diseases
C0796611 BXGD010835 Newly Diagnosed Childhood Ependymoma Neoplasms
C0854135 BXGD011002 Pseudomonas aeruginosa infection Infections
C0854211 BXGD011008 Bacterial keratitis Pathological Conditions, Signs and Symptoms; Infections; Eye Diseases
C0877056 BXGD011334 Hypoglycemic seizures Nutritional and Metabolic Diseases
C0947751 BXGD011494 Vascular inflammations Cardiovascular Diseases
C0948008 BXGD011499 Ischemic stroke Nervous System Diseases; Cardiovascular Diseases
C0948089 BXGD011504 Acute Coronary Syndrome Cardiovascular Diseases
C0948379 BXGD011533 Impaired insulin secretion
C0949690 BXGD011584 Spondylarthritis Musculoskeletal Diseases
C0949691 BXGD011585 Spondylarthropathies Musculoskeletal Diseases
C1141926 BXGD011723 Abdominal sepsis
C1262477 BXGD011882 Weight decreased Pathological Conditions, Signs and Symptoms
C1263857 BXGD011900 Peripheral axonal neuropathy Nervous System Diseases
C1290884 BXGD012198 Inflammatory disorder Pathological Conditions, Signs and Symptoms
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1384666 BXGD012948 hearing impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C1445957 BXGD013081 Serum total cholesterol measurement
C1527311 BXGD013268 Brain Edema Nervous System Diseases
C1536220 BXGD013341 ST segment elevation myocardial infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C1611743 BXGD013456 Familial (FPAH)
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1720983 BXGD013698 Channelopathies Pathological Conditions, Signs and Symptoms
C1740821 BXGD013745 Slowly progressive insulin dependent diabetes
C1832386 BXGD013834 Diabetes Mellitus, Transient Neonatal, 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Endocrine System Diseases
C1832661 BXGD013866 ANOPHTHALMIA AND PULMONARY HYPOPLASIA Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Respiratory Tract Diseases
C1833102 BXGD013895 DIABETES MELLITUS, PERMANENT NEONATAL, WITH NEUROLOGIC FEATURES Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases; Nervous System Diseases; Endocrine System Diseases
C1833104 BXGD013896 DIABETES MELLITUS, PERMANENT NEONATAL Nutritional and Metabolic Diseases; Endocrine System Diseases
C1835884 BXGD014061 Triangular face
C1835887 BXGD014062 DIABETES MELLITUS, TRANSIENT NEONATAL, 2 (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Endocrine System Diseases
C1836189 BXGD014091 Radial deviation of finger
C1836623 BXGD014139 Decreased circulating cortisol level Immune System Diseases; Endocrine System Diseases
C1840077 BXGD014434 Anteverted nostril
C1844505 BXGD014633 Pointed chin
C1847425 BXGD014865 Abnormal oral glucose tolerance
C1847555 BXGD014875 Hyperinsulinemic hypoglycemia, familial, 6 Nutritional and Metabolic Diseases
C1848395 BXGD014921 Large for gestational age Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications
C1849089 BXGD015004 Broad forehead
C1851584 BXGD015221 Childhood Ependymoma Neoplasms
C1853564 BXGD015345 Developmental Delay, Epilepsy, and Neonatal Diabetes Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases; Endocrine System Diseases; Behavior and Behavior Mechanisms
C1853743 BXGD015358 Muscular hypotonia of the trunk Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1854114 BXGD015383 Short nose
C1854301 BXGD015391 Motor delay Mental Disorders
C1854838 BXGD015438 Progressive neurologic deterioration Mental Disorders
C1856438 BXGD015606 Hypoketotic hypoglycemia Nutritional and Metabolic Diseases
C1856904 BXGD015654 Reduced pancreatic beta cells
C1857949 BXGD015758 Prominent metopic ridge
C1858120 BXGD015774 Generalized hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1858361 BXGD015784 Pyogenic Arthritis, Pyoderma Gangrenosum and Acne Infections; Skin and Connective Tissue Diseases; Musculoskeletal Diseases
C1859523 BXGD015908 Contractures of the joints of the lower limbs
C1864623 BXGD016238 DIABETES MELLITUS, TRANSIENT NEONATAL, 3 (disorder) Nutritional and Metabolic Diseases; Endocrine System Diseases
C1864903 BXGD016270 Hyperinsulinemic hypoglycemia Nutritional and Metabolic Diseases
C1865014 BXGD016282 Long philtrum
C1865916 BXGD016355 Bilateral ptosis Eye Diseases
C1866195 BXGD016385 Downturned corners of mouth
C1961102 BXGD016673 Precursor Cell Lymphoblastic Leukemia Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1962966 BXGD016678 Retinopathy, CTCAE
C1963060 BXGD016679 Agitation, CTCAE 3.0
C1969372 BXGD016775 Tubulointerstitial fibrosis
C1969875 BXGD016798 Beta-cell dysfunction
C1969879 BXGD016799 Limb joint contracture
C2004493 BXGD016875 Leukemia, B-Cell Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C2243051 BXGD017008 Large head (disorder)
C2267233 BXGD017017 Neonatal Hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C2700617 BXGD017474 Irritation - emotion Behavior and Behavior Mechanisms
C2745900 BXGD017568 Promyelocytic leukemia
C2748055 BXGD017583 Hypoinsulinaemia (disorder)
C2830004 BXGD017804 Somnolence Pathological Conditions, Signs and Symptoms
C2931207 BXGD017979 Usher syndrome, type 1C Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Nervous System Diseases; Otorhinolaryngologic Diseases
C2931832 BXGD018070 Hyperinsulinemic hypoglycemia, familial, 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Nutritional and Metabolic Diseases
C2931833 BXGD018071 Hyperinsulinemic hypoglycemia, familial, 2 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Nutritional and Metabolic Diseases
C2936719 BXGD018130 Mechanical Allodynia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C2973725 BXGD018205 Pulmonary arterial hypertension Respiratory Tract Diseases; Cardiovascular Diseases
C3203102 BXGD018555 Idiopathic pulmonary arterial hypertension Respiratory Tract Diseases
C3278636 BXGD018744 Neonatal insulin-dependent diabetes mellitus
C3494422 BXGD018966 Retrognathia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C3495427 BXGD018984 Fanconi-Bickel Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C3808403 BXGD019546 Large fleshy ears
C3837958 BXGD019756 Diabetes Mellitus, Ketosis-Prone Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C3887499 BXGD019884 Renal cyst Pathological Conditions, Signs and Symptoms; Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C3888018 BXGD019942 Congenital Hyperinsulinism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Nutritional and Metabolic Diseases
C3888631 BXGD019983 Monogenic diabetes Nutritional and Metabolic Diseases; Endocrine System Diseases
C3896643 BXGD020040 New Onset Diabetes After Transplant Nutritional and Metabolic Diseases; Endocrine System Diseases
C4012968 BXGD020124 Mild global developmental delay
C4021753 BXGD020758 Abnormality of the immune system
C4021759 BXGD020762 Generalized myoclonic seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C4022484 BXGD020905 Clinodactyly of the 4th finger
C4022798 BXGD021001 Abnormal brain FDG positron emission tomography
C4024168 BXGD021296 Thickened ears
C4024716 BXGD021383 Secondary growth hormone deficiency
C4025043 BXGD021533 Abnormality of the pancreatic islet cells
C4073162 BXGD022053 Elevated hemoglobin A1c
C4274080 BXGD022342 Autosomal dominant hyperinsulinism due to SUR1 deficiency Nutritional and Metabolic Diseases
C4280765 BXGD022402 Abnormal C-peptide level
C4281993 BXGD022418 Neonatal respiratory distress Respiratory Tract Diseases
C4303593 BXGD022566 DEND syndrome Nervous System Diseases
C4317146 BXGD022730 Acid reflux
C4321446 BXGD022751 K ATP Permanent Neonatal Diabetes
C4551485 BXGD023312 Clinodactyly
C4552000 BXGD023473 Episodic Kinesigenic Dyskinesia 1 Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C4552810 BXGD023525 Irritability, CTCAE
C4552855 BXGD023528 Agitation, CTCAE 5.0
C4553743 BXGD023548 Spasticity, CTCAE
C4554117 BXGD023561 Diabetes Mellitus, Sudden-Onset Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C4703473 BXGD023650 Atherosclerotic lesion Cardiovascular Diseases
C4703555 BXGD023658 Decreased waist to hip ratio
C4721453 BXGD023744 Peripheral Nervous System Diseases Nervous System Diseases
C4728082 BXGD023886 Severe hypoglycaemia
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0001497 Berberrubine 322.33
BXGC0002588 Magnesium 24.31
BXGC0027374 Glyburide 493.14
BXGC0028612 Canadine 339.15
BXGC0039684 Berberine Chloride 336.12
BXGC0042519 Glimepiride 490.22
BXGC0043055 Palmatine Chloride 352.15
BXGC0044218 demethyleneberberine 324.12
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein