Showing entry for Childhood Ependymoma


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD015221
Disease NameChildhood Ependymoma
Disease CUI IdC1851584
MeSH Codes C04  
Disease Class NameNeoplasms
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7   DOID:14566  
Disease Ontology Class Namedisease of anatomical entity; disease of cellular proliferation
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00255 BXGT003903 Menin 4221 reviewed
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O14745 BXGT004090 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 9368 reviewed
O75874 BXGT005157 Isocitrate dehydrogenase [NADP] cytoplasmic 3417 reviewed
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P00747 BXGT005639 Plasminogen 5340 reviewed Enzyme
P02766 BXGT005953 Transthyretin 7276 reviewed Transporter
P04271 BXGT006177 Protein S100-B 6285 reviewed Calcium-binding protein
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P05231 BXGT006345 Interleukin-6 3569 reviewed
P06703 BXGT006477 Protein S100-A6 6277 reviewed Calcium-binding protein
P08183 BXGT006741 ATP-dependent translocase ABCB1 5243 reviewed Transporter
P08473 BXGT006773 Neprilysin 4311 reviewed Enzyme
P08581 BXGT006794 Hepatocyte growth factor receptor 4233 reviewed Kinase
P09619 BXGT006911 Platelet-derived growth factor receptor beta 5159 reviewed Kinase
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10721 BXGT007605 Mast/stem cell growth factor receptor Kit 3815 reviewed Kinase
P11137 BXGT007656 Microtubule-associated protein 2 4133 reviewed
P11362 BXGT007693 Fibroblast growth factor receptor 1 2260 reviewed Kinase
P12314 BXGT007798 High affinity immunoglobulin gamma Fc receptor I 2209 reviewed Cell adhesion
P14416 BXGT008011 D(2) dopamine receptor 1813 reviewed G-protein coupled receptor
P14550 BXGT008019 Aldo-keto reductase family 1 member A1 10327 reviewed Enzyme
P15153 BXGT008090 Ras-related C3 botulinum toxin substrate 2 5880 reviewed Enzyme modulator
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P15941 BXGT008176 Mucin-1 4582 reviewed
P16070 BXGT008186 CD44 antigen 960 reviewed
P16234 BXGT008209 Platelet-derived growth factor receptor alpha 5156 reviewed Kinase
P16455 BXGT008229 Methylated-DNA--protein-cysteine methyltransferase 4255 reviewed
P21728 BXGT008686 D(1A) dopamine receptor 1812 reviewed G-protein coupled receptor
P22607 BXGT008784 Fibroblast growth factor receptor 3 2261 reviewed Kinase
P23297 BXGT008848 Protein S100-A1 6271 reviewed Calcium-binding protein
P23921 BXGT008927 Ribonucleoside-diphosphate reductase large subunit 6240 reviewed Enzyme
P24385 BXGT008965 G1/S-specific cyclin-D1 595 reviewed Enzyme modulator
P26447 BXGT009114 Protein S100-A4 6275 reviewed Calcium-binding protein
P27797 BXGT009206 Calreticulin 811 reviewed Calcium-binding protein
P28222 BXGT009238 5-hydroxytryptamine receptor 1B 3351 reviewed G-protein coupled receptor
P29034 BXGT009309 Protein S100-A2 6273 reviewed Calcium-binding protein
P29323 BXGT009334 Ephrin type-B receptor 2 2048 reviewed Kinase
P30988 BXGT009491 Calcitonin receptor 799 reviewed G-protein coupled receptor
P32004 BXGT009594 Neural cell adhesion molecule L1 3897 reviewed
P35968 BXGT009887 Vascular endothelial growth factor receptor 2 3791 reviewed Kinase
P36222 BXGT009914 Chitinase-3-like protein 1 1116 reviewed
P37840 BXGT010015 Alpha-synuclein 6622 reviewed Transporter
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P46100 BXGT010508 Transcriptional regulator ATRX 546 reviewed
P46531 BXGT010526 Neurogenic locus notch homolog protein 1 4851 reviewed
P46937 BXGT010554 Transcriptional coactivator YAP1 10413 reviewed Enzyme modulator
P48029 BXGT010606 Sodium- and chloride-dependent creatine transporter 1 6535 reviewed Transporter
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P53355 BXGT010985 Death-associated protein kinase 1 1612 reviewed Kinase
P57059 BXGT011210 Serine/threonine-protein kinase SIK1 150094 reviewed
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P78504 BXGT011844 Protein jagged-1 182 reviewed
Q00534 BXGT012533 Cyclin-dependent kinase 6 1021 reviewed Kinase
Q00987 BXGT012559 E3 ubiquitin-protein ligase Mdm2 4193 reviewed Nucleic acid binding
Q04206 BXGT012754 Transcription factor p65 5970 reviewed Transcription factor
Q09428 BXGT013036 ATP-binding cassette sub-family C member 8 6833 reviewed Transporter
Q13509 BXGT013366 Tubulin beta-3 chain 10381 reviewed Cellular structure
Q13510 BXGT013367 Acid ceramidase 427 reviewed Enzyme
Q13569 BXGT013378 G/T mismatch-specific thymine DNA glycosylase 6996 reviewed
Q13938 BXGT013405 Calcyphosin 828 reviewed
Q14790 BXGT013505 Caspase-8 841 reviewed Enzyme
Q15303 BXGT013557 Receptor tyrosine-protein kinase erbB-4 2066 reviewed Kinase
Q15465 BXGT013573 Sonic hedgehog protein 6469 reviewed
Q15910 BXGT013612 Histone-lysine N-methyltransferase EZH2 2146 reviewed Epigenetic regulator
Q16637 BXGT013646 Survival motor neuron protein 6607 reviewed Epigenetic regulator
Q6N021 BXGT016378 Methylcytosine dioxygenase TET2 54790 reviewed
Q6ZQY3 BXGT016636 Acidic amino acid decarboxylase GADL1 339896 reviewed
Q96A70 BXGT019615 Antizyme inhibitor 2 113451 reviewed Enzyme
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9UI32 BXGT021711 Glutaminase liver isoform, mitochondrial 27165 reviewed Enzyme
Q9Y219 BXGT022206 Protein jagged-2 3714 reviewed
P35240 BXGT022927 Merlin 4771 reviewed
P25054 BXGT022961 Adenomatous polyposis coli protein 324 reviewed
P09471 BXGT026153 Guanine nucleotide-binding protein G(o) subunit alpha 2775 reviewed Enzyme modulator
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease