Showing entry for 5-hydroxytryptamine receptor 2A


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT008059
Protein Name5-hydroxytryptamine receptor 2A
Uniport IdP14842
GeneHtr2a
Gene Id29595
Domain7tm_1
Pfam PF00001  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007202 activation of phospholipase C activity
Biological Process GO:0007568 aging
Biological Process GO:0014824 artery smooth muscle contraction
Biological Process GO:0048148 behavioral response to cocaine
Biological Process GO:0008219 cell death
Biological Process GO:0006874 cellular calcium ion homeostasis
Biological Process GO:0007268 chemical synaptic transmission
Biological Process GO:0050966 detection of mechanical stimulus involved in sensory perception of pain
Biological Process GO:0050965 detection of temperature stimulus involved in sensory perception of pain
Biological Process GO:0007186 G protein-coupled receptor signaling pathway
Biological Process GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
Biological Process GO:0007613 memory
Biological Process GO:0043267 negative regulation of potassium ion transport
Biological Process GO:0051967 negative regulation of synaptic transmission, glutamatergic
Biological Process GO:0014065 phosphatidylinositol 3-kinase signaling
Biological Process GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway
Biological Process GO:0007208 phospholipase C-activating serotonin receptor signaling pathway
Biological Process GO:0008284 positive regulation of cell population proliferation
Biological Process GO:0007204 positive regulation of cytosolic calcium ion concentration
Biological Process GO:0070374 positive regulation of ERK1 and ERK2 cascade
Biological Process GO:0045600 positive regulation of fat cell differentiation
Biological Process GO:0045821 positive regulation of glycolytic process
Biological Process GO:0033674 positive regulation of kinase activity
Biological Process GO:0043406 positive regulation of MAP kinase activity
Biological Process GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
Biological Process GO:0010513 positive regulation of phosphatidylinositol biosynthetic process
Biological Process GO:0045907 positive regulation of vasoconstriction
Biological Process GO:0044380 protein localization to cytoskeleton
Biological Process GO:0014059 regulation of dopamine secretion
Biological Process GO:2000300 regulation of synaptic vesicle exocytosis
Biological Process GO:0051209 release of sequestered calcium ion into cytosol
Biological Process GO:0042493 response to drug
Biological Process GO:0019233 sensory perception of pain
Biological Process GO:0007210 serotonin receptor signaling pathway
Biological Process GO:0030431 sleep
Biological Process GO:0001659 temperature homeostasis
Biological Process GO:0014832 urinary bladder smooth muscle contraction
molecular function GO:0071886 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding
molecular function GO:0008144 drug binding
molecular function GO:0001965 G-protein alpha-subunit binding
molecular function GO:0004930 G protein-coupled receptor activity
molecular function GO:0004993 G protein-coupled serotonin receptor activity
molecular function GO:0042802 identical protein binding
molecular function GO:0030594 neurotransmitter receptor activity
molecular function GO:0044877 protein-containing complex binding
molecular function GO:0051378 serotonin binding
cellular component GO:0030424 axon
cellular component GO:0005901 caveola
cellular component GO:0070852 cell body fiber
cellular component GO:0005737 cytoplasm
cellular component GO:0031410 cytoplasmic vesicle
cellular component GO:0005829 cytosol
cellular component GO:0030425 dendrite
cellular component GO:0043198 dendritic shaft
cellular component GO:0098978 glutamatergic synapse
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0099056 integral component of presynaptic membrane
cellular component GO:0016020 membrane
cellular component GO:0043025 neuronal cell body
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000191 Tyramine 137.18
BXGC0000548 Tryptamine 160.22
BXGC0000651 Harmalan 184.24
BXGC0000982 L-Homocysteine 135.19
BXGC0001327 Nonacosan-8-one 165.23
BXGC0001545 Harmine 212.25
BXGC0002916 Melatonin 232.28
BXGC0003196 Aripiprazole 448.39
BXGC0003501 Parthenolide 248.32
BXGC0004757 2-Aminoacetophenone 135.16
BXGC0004760 2-Phenylethylamine 121.18
BXGC0005867 Serotonin 176.22
BXGC0005871 Dopamine 153.18
BXGC0005874 Racemethionine 149.21
BXGC0006109 2-Aminoquinoline 144.17
BXGC0006183 L-Cystine 240.3
BXGC0009318 Nb-Methylserotonin 190.24
BXGC0010227 Etrogol 206.28
BXGC0013070 Mescaline 211.12
BXGC0014068 Amphetamine 135.1
BXGC0016891 Nortriptyline 263.17
BXGC0018063 Alprenolol 249.17
BXGC0019461 Heptadec-9-Ene-4,6-Diyne-1,8-Diol 262.19
BXGC0020654 Dopa 197.07
BXGC0022192 Bufotenine 204.13
BXGC0026443 (S)-2-Amino-1-phenylethanol 137.08
BXGC0027950 1-(2,3-Dimethoxyphenyl)Propan-2-Amine 195.13
BXGC0028943 1-(3-Methoxyphenyl)Propan-2-Amine 165.12
BXGC0032808 cathinone 149.08
BXGC0034989 N-Methylmescaline 225.14
BXGC0035358 1-(4-Ethoxyphenyl)Propan-2-Amine 179.13
BXGC0038001 17-Hydroxy-Heptadeca-7,9-Diene-11,13-Diyn-4-One 258.16
BXGC0038892 (1R,2S)-Phenylpropanolamine 151.1
BXGC0038909 1-(4-methylphenyl)propane-2-amine 149.12
BXGC0038980 cathinone 149.08
BXGC0039091 1-(3,4,5-Trimethoxyphenyl)Propan-2-Amine 225.14
BXGC0042222 Propranolol 259.16
BXGC0042462 Cysteine 121.02
BXGC0042510 Fluoxetine 309.13
BXGC0043954 2-(4-Methoxyphenyl)Ethanamine 151.1
BXGC0045489 [(8E,10E,12E,14R)-14-Hydroxyheptadeca-8,10,12-Trien-4,6-Diynyl] Acetate 300.17
BXGC0045812 Trifluoperazine 407.16
BXGC0046755 Yohimbine 354.19
BXGC0050172 N,N-Dimethyltryptamine 188.13
BXGC0052374 Reserpine 608.27
BXGC0052798 5-Meo-Dmt 218.14
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein