Showing entry for Myocardial Reperfusion Injury


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD001964
Disease NameMyocardial Reperfusion Injury
Disease CUI IdC0027055
MeSH Codes C23   C14  
Disease Class NamePathological Conditions, Signs and Symptoms; Cardiovascular Diseases
Semantic TypePathologic Function
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O14939 BXGT004115 Phospholipase D2 5338 reviewed
O15123 BXGT004130 Angiopoietin-2 285 reviewed Signaling
O60603 BXGT004887 Toll-like receptor 2 7097 reviewed
O60674 BXGT004892 Tyrosine-protein kinase JAK2 3717 reviewed Kinase
O95831 BXGT005399 Apoptosis-inducing factor 1, mitochondrial 9131 reviewed Enzyme
P00390 BXGT005526 Glutathione reductase, mitochondrial 2936 reviewed Enzyme
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] 6647 reviewed Enzyme
P00813 BXGT005667 Adenosine deaminase 100 reviewed Enzyme
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P01024 BXGT005719 Complement C3 718 reviewed Enzyme modulator
P01031 BXGT005720 Complement C5 727 reviewed Enzyme modulator
P01042 BXGT005722 Kininogen-1 3827 reviewed Enzyme modulator
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P02144 BXGT005853 Myoglobin 4151 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P02786 BXGT005961 Transferrin receptor protein 1 7037 reviewed Enzyme
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P03956 BXGT006120 Interstitial collagenase 4312 reviewed Enzyme
P04040 BXGT006132 Catalase 847 reviewed Enzyme
P04083 BXGT006147 Annexin A1 301 reviewed
P04271 BXGT006177 Protein S100-B 6285 reviewed Calcium-binding protein
P04406 BXGT006207 Glyceraldehyde-3-phosphate dehydrogenase 2597 reviewed Enzyme
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04839 BXGT006273 Cytochrome b-245 heavy chain 1536 reviewed Ion channel
P05023 BXGT006294 Sodium/potassium-transporting ATPase subunit alpha-1 476 reviewed Transporter
P05091 BXGT006312 Aldehyde dehydrogenase, mitochondrial 217 reviewed Enzyme
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05362 BXGT006350 Intercellular adhesion molecule 1 3383 reviewed
P05771 BXGT006384 Protein kinase C beta type 5579 reviewed Kinase
P07550 BXGT006636 Beta-2 adrenergic receptor 154 reviewed G-protein coupled receptor
P07996 BXGT006710 Thrombospondin-1 7057 reviewed
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08588 BXGT006795 Beta-1 adrenergic receptor 153 reviewed G-protein coupled receptor
P09429 BXGT006889 High mobility group protein B1 3146 reviewed Nucleic acid binding
P09601 BXGT006909 Heme oxygenase 1 3162 reviewed
P09917 BXGT006941 Arachidonate 5-lipoxygenase 240 reviewed Enzyme
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10599 BXGT007583 Thioredoxin 7295 reviewed
P11021 BXGT007644 Endoplasmic reticulum chaperone BiP 3309 reviewed
P11166 BXGT007661 Solute carrier family 2, facilitated glucose transporter member 1 6513 reviewed Transporter
P12235 BXGT007774 ADP/ATP translocase 1 291 reviewed Transporter
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P14672 BXGT008037 Solute carrier family 2, facilitated glucose transporter member 4 6517 reviewed Transporter
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P16109 BXGT008194 P-selectin 6403 reviewed
P16157 BXGT008203 Ankyrin-1 286 reviewed
P17342 BXGT008302 Atrial natriuretic peptide receptor 3 4883 reviewed
P18847 BXGT008431 Cyclic AMP-dependent transcription factor ATF-3 467 reviewed Transcription factor
P19320 BXGT008470 Vascular cell adhesion protein 1 7412 reviewed
P19634 BXGT008504 Sodium/hydrogen exchanger 1 6548 reviewed Transporter
P20810 BXGT008602 Calpastatin 831 reviewed
P21554 BXGT008662 Cannabinoid receptor 1 1268 reviewed G-protein coupled receptor
P21796 BXGT008690 Voltage-dependent anion-selective channel protein 1 7416 reviewed
P24530 BXGT008975 Endothelin receptor type B 1910 reviewed G-protein coupled receptor
P25098 BXGT009015 Beta-adrenergic receptor kinase 1 156 reviewed Kinase
P25101 BXGT009018 Endothelin-1 receptor 1909 reviewed G-protein coupled receptor
P25929 BXGT009078 Neuropeptide Y receptor type 1 4886 reviewed G-protein coupled receptor
P25963 BXGT009080 NF-kappa-B inhibitor alpha 4792 reviewed
P27361 BXGT009176 Mitogen-activated protein kinase 3 5595 reviewed Kinase
P27695 BXGT009199 DNA-(apurinic or apyrimidinic site) lyase 328 reviewed
P28331 BXGT009252 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial 4719 reviewed Enzyme
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P29466 BXGT009349 Caspase-1 834 reviewed Enzyme
P29474 BXGT009352 Nitric oxide synthase, endothelial 4846 reviewed
P30101 BXGT009402 Protein disulfide-isomerase A3 2923 reviewed
P30556 BXGT009441 Type-1 angiotensin II receptor 185 reviewed G-protein coupled receptor
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P31751 BXGT009576 RAC-beta serine/threonine-protein kinase 208 reviewed Kinase
P32418 BXGT009635 Sodium/calcium exchanger 1 6546 reviewed Transporter
P34913 BXGT009770 Bifunctional epoxide hydrolase 2 2053 reviewed Enzyme
P34972 BXGT009779 Cannabinoid receptor 2 1269 reviewed G-protein coupled receptor
P35228 BXGT009800 Nitric oxide synthase, inducible 4843 reviewed
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35573 BXGT009850 Glycogen debranching enzyme 178 reviewed Enzyme
P35754 BXGT009863 Glutaredoxin-1 2745 reviewed
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P41143 BXGT010223 Delta-type opioid receptor 4985 reviewed G-protein coupled receptor
P41180 BXGT010230 Extracellular calcium-sensing receptor 846 reviewed G-protein coupled receptor
P42224 BXGT010286 Signal transducer and activator of transcription 1-alpha/beta 6772 reviewed Nucleic acid binding
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P43115 BXGT010356 Prostaglandin E2 receptor EP3 subtype 5733 reviewed G-protein coupled receptor
P45983 BXGT010494 Mitogen-activated protein kinase 8 5599 reviewed Kinase
P47989 BXGT010602 Xanthine dehydrogenase/oxidase 7498 reviewed Enzyme
P48357 BXGT010627 Leptin receptor 3953 reviewed Signaling
P49841 BXGT010750 Glycogen synthase kinase-3 beta 2932 reviewed Kinase
P51451 BXGT010848 Tyrosine-protein kinase Blk 640 reviewed Kinase
P51617 BXGT010868 Interleukin-1 receptor-associated kinase 1 3654 reviewed Kinase
P51681 BXGT010878 C-C chemokine receptor type 5 1234 reviewed G-protein coupled receptor
P51884 BXGT010903 Lumican 4060 reviewed
P55210 BXGT011110 Caspase-7 840 reviewed Enzyme
P55211 BXGT011111 Caspase-9 842 reviewed Enzyme
P55957 BXGT011137 BH3-interacting domain death agonist 637 reviewed
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P61586 BXGT011375 Transforming protein RhoA 387 reviewed Enzyme modulator
P62834 BXGT011464 Ras-related protein Rap-1A 5906 reviewed Enzyme modulator
P78380 BXGT011841 Oxidized low-density lipoprotein receptor 1 4973 reviewed
P84022 BXGT012027 Mothers against decapentaplegic homolog 3 4088 reviewed Transcription factor
P98170 BXGT012231 E3 ubiquitin-protein ligase XIAP 331 reviewed Enzyme modulator
Q00796 BXGT012549 Sorbitol dehydrogenase 6652 reviewed Enzyme
Q00987 BXGT012559 E3 ubiquitin-protein ligase Mdm2 4193 reviewed Nucleic acid binding
Q01484 BXGT012592 Ankyrin-2 287 reviewed
Q02763 BXGT012667 Angiopoietin-1 receptor 7010 reviewed Kinase
Q03181 BXGT012701 Peroxisome proliferator-activated receptor delta 5467 reviewed Nuclear receptor
Q04206 BXGT012754 Transcription factor p65 5970 reviewed Transcription factor
Q05655 BXGT012832 Protein kinase C delta type 5580 reviewed Kinase
Q07812 BXGT012940 Apoptosis regulator BAX 581 reviewed Signaling
Q07817 BXGT012941 Bcl-2-like protein 1 598 reviewed Signaling
Q07869 BXGT012945 Peroxisome proliferator-activated receptor alpha 5465 reviewed Nuclear receptor
Q13485 BXGT013363 Mothers against decapentaplegic homolog 4 4089 reviewed Transcription factor
Q13976 BXGT013409 cGMP-dependent protein kinase 1 5592 reviewed Kinase
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q14457 BXGT013472 Beclin-1 8678 reviewed Enzyme modulator
Q14790 BXGT013505 Caspase-8 841 reviewed Enzyme
Q15109 BXGT013537 Advanced glycosylation end product-specific receptor 177 reviewed Receptor
Q15465 BXGT013573 Sonic hedgehog protein 6469 reviewed
Q15842 BXGT013607 ATP-sensitive inward rectifier potassium channel 8 3764 reviewed Ion channel
Q15848 BXGT013609 Adiponectin 9370 reviewed
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q92934 BXGT019396 Bcl2-associated agonist of cell death 572 reviewed
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q99757 BXGT019959 Thioredoxin, mitochondrial 25828 reviewed Enzyme
Q99836 BXGT019970 Myeloid differentiation primary response protein MyD88 4615 reviewed Enzyme modulator
Q9H492 BXGT020472 Microtubule-associated proteins 1A/1B light chain 3A 84557 reviewed Cellular structure
Q9NR28 BXGT021178 Diablo homolog, mitochondrial 56616 reviewed
Q9UNN8 BXGT021791 Endothelial protein C receptor 10544 reviewed Enzyme modulator
Q9Y5N1 BXGT022297 Histamine H3 receptor 11255 reviewed G-protein coupled receptor
P16284 BXGT022972 Platelet endothelial cell adhesion molecule 5175 reviewed Cell adhesion
P19875 BXGT023294 C-X-C motif chemokine 2 2920 reviewed Signaling
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
P16615 BXGT023653 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 488 reviewed Transporter
O95399 BXGT024237 Urotensin-2 10911 reviewed
Q9UKP6 BXGT024239 Urotensin-2 receptor 2837 reviewed G-protein coupled receptor
O95140 BXGT024482 Mitofusin-2 9927 reviewed Enzyme
P16104 BXGT024571 Histone H2AX 3014 reviewed Nucleic acid binding
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease