adisease

Showing entry for Memory Loss

General Disease Information
BXGD Id	BXGD010383
Disease Name	Memory Loss
Disease CUI Id	C0751295
MeSH Codes	C23 C10 F01
Disease Class Name	Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
Semantic Type	Sign or Symptom
Human Phenotype Ontology Id	HP:0000707
Human Phenotype Ontology Term	Abnormality of the nervous system
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O14646	BXGT004079	Chromodomain-helicase-DNA-binding protein 1	1105	reviewed
O60260	BXGT004864	E3 ubiquitin-protein ligase parkin	5071	reviewed	Enzyme
O95257	BXGT005365	Growth arrest and DNA damage-inducible protein GADD45 gamma	10912	reviewed
O95631	BXGT005387	Netrin-1	9423	reviewed	Enzyme modulator
O95970	BXGT005409	Leucine-rich glioma-inactivated protein 1	9211	reviewed
P00441	BXGT005540	Superoxide dismutase [Cu-Zn]	6647	reviewed	Enzyme
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P01138	BXGT005738	Beta-nerve growth factor	4803	reviewed	Signaling
P01303	BXGT005748	Pro-neuropeptide Y	4852	reviewed	Signaling
P01308	BXGT005749	Insulin	3630	reviewed
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P02818	BXGT005969	Osteocalcin	632	reviewed
P04155	BXGT006155	Trefoil factor 1	7031	reviewed	Signaling
P04440	BXGT006216	HLA class II histocompatibility antigen, DP beta 1 chain	3115	reviewed	Immune response
P05067	BXGT006306	Amyloid-beta precursor protein	351	reviewed	Enzyme modulator
P05091	BXGT006312	Aldehyde dehydrogenase, mitochondrial	217	reviewed	Enzyme
P05107	BXGT006316	Integrin beta-2	3689	reviewed	Receptor
P05231	BXGT006345	Interleukin-6	3569	reviewed
P05937	BXGT006396	Calbindin	793	reviewed	Calcium-binding protein
P07333	BXGT006602	Macrophage colony-stimulating factor 1 receptor	1436	reviewed	Kinase
P07858	BXGT006689	Cathepsin B	1508	reviewed	Enzyme
P07900	BXGT006696	Heat shock protein HSP 90-alpha	3320	reviewed	Chaperone
P08069	BXGT006723	Insulin-like growth factor 1 receptor	3480	reviewed	Kinase
P08908	BXGT006837	5-hydroxytryptamine receptor 1A	3350	reviewed	G-protein coupled receptor
P09429	BXGT006889	High mobility group protein B1	3146	reviewed	Nucleic acid binding
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P10636	BXGT007596	Microtubule-associated protein tau	4137	reviewed
P11215	BXGT007672	Integrin alpha-M	3684	reviewed
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	1128	reviewed	G-protein coupled receptor
P11597	BXGT007727	Cholesteryl ester transfer protein	1071	reviewed
P14174	BXGT007991	Macrophage migration inhibitory factor	4282	reviewed
P14416	BXGT008011	D(2) dopamine receptor	1813	reviewed	G-protein coupled receptor
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P16083	BXGT008187	Ribosyldihydronicotinamide dehydrogenase [quinone]	4835	reviewed
P16220	BXGT008206	Cyclic AMP-responsive element-binding protein 1	1385	reviewed
P18031	BXGT008369	Tyrosine-protein phosphatase non-receptor type 1	5770	reviewed
P20472	BXGT008578	Parvalbumin alpha	5816	reviewed	Calcium-binding protein
P21554	BXGT008662	Cannabinoid receptor 1	1268	reviewed	G-protein coupled receptor
P21964	BXGT008714	Catechol O-methyltransferase	1312	reviewed	Enzyme
P22303	BXGT008751	Acetylcholinesterase	43	reviewed	Enzyme
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P24158	BXGT008951	Myeloblastin	5657	reviewed	Enzyme
P27815	BXGT009208	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	5141	reviewed
P28482	BXGT009263	Mitogen-activated protein kinase 1	5594	reviewed	Kinase
P28845	BXGT009297	Corticosteroid 11-beta-dehydrogenase isozyme 1	3290	reviewed
P29323	BXGT009334	Ephrin type-B receptor 2	2048	reviewed	Kinase
P29466	BXGT009349	Caspase-1	834	reviewed	Enzyme
P31644	BXGT009557	Gamma-aminobutyric acid receptor subunit alpha-5	2558	reviewed	Ion channel
P31645	BXGT009558	Sodium-dependent serotonin transporter	6532	reviewed	Transporter
P34969	BXGT009777	5-hydroxytryptamine receptor 7	3363	reviewed	G-protein coupled receptor
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P37840	BXGT010015	Alpha-synuclein	6622	reviewed	Transporter
P39687	BXGT010131	Acidic leucine-rich nuclear phosphoprotein 32 family member A	8125	reviewed	Enzyme modulator
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P42262	BXGT010294	Glutamate receptor 2	2891	reviewed	Ion channel
P42345	BXGT010304	Serine/threonine-protein kinase mTOR	2475	reviewed	Kinase
P42575	BXGT010318	Caspase-2	835	reviewed	Enzyme
P42898	BXGT010344	Methylenetetrahydrofolate reductase	4524	reviewed
P45983	BXGT010494	Mitogen-activated protein kinase 8	5599	reviewed	Kinase
P46108	BXGT010509	Adapter molecule crk	1398	reviewed
P49768	BXGT010740	Presenilin-1	5663	reviewed	Enzyme
P49810	BXGT010747	Presenilin-2	5664	reviewed	Enzyme
P49841	BXGT010750	Glycogen synthase kinase-3 beta	2932	reviewed	Kinase
P50406	BXGT010796	5-hydroxytryptamine receptor 6	3362	reviewed	G-protein coupled receptor
P54646	BXGT011062	5'-AMP-activated protein kinase catalytic subunit alpha-2	5563	reviewed	Kinase
P54829	BXGT011085	Tyrosine-protein phosphatase non-receptor type 5	84867	reviewed
P56817	BXGT011200	Beta-secretase 1	23621	reviewed	Enzyme
P60709	BXGT011322	Actin, cytoplasmic 1	60	reviewed	Cellular structure
P63000	BXGT011481	Ras-related C3 botulinum toxin substrate 1	5879	reviewed	Enzyme modulator
P78504	BXGT011844	Protein jagged-1	182	reviewed
Q00535	BXGT012534	Cyclin-dependent-like kinase 5	1020	reviewed	Kinase
Q00613	BXGT012540	Heat shock factor protein 1	3297	reviewed	Transcription factor
Q01959	BXGT012624	Sodium-dependent dopamine transporter	6531	reviewed	Transporter
Q04609	BXGT012768	Glutamate carboxypeptidase 2	2346	reviewed	Enzyme
Q05329	BXGT012814	Glutamate decarboxylase 2	2572	reviewed	Enzyme
Q06787	BXGT012890	Synaptic functional regulator FMR1	2332	reviewed	Nucleic acid binding
Q09028	BXGT013025	Histone-binding protein RBBP4	5928	reviewed
Q12791	BXGT013264	Calcium-activated potassium channel subunit alpha-1	3778	reviewed	Ion channel
Q13131	BXGT013314	5'-AMP-activated protein kinase catalytic subunit alpha-1	5562	reviewed	Kinase
Q13148	BXGT013318	TAR DNA-binding protein 43	23435	reviewed
Q13155	BXGT013320	Aminoacyl tRNA synthase complex-interacting multifunctional protein 2	7965	reviewed
Q13224	BXGT013328	Glutamate receptor ionotropic, NMDA 2B	2904	reviewed	Ion channel
Q14416	BXGT013468	Metabotropic glutamate receptor 2	2912	reviewed	G-protein coupled receptor
Q14832	BXGT013507	Metabotropic glutamate receptor 3	2913	reviewed	G-protein coupled receptor
Q15109	BXGT013537	Advanced glycosylation end product-specific receptor	177	reviewed	Receptor
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	4780	reviewed	Enzyme
Q16539	BXGT013634	Mitogen-activated protein kinase 14	1432	reviewed	Kinase
Q16620	BXGT013645	BDNF/NT-3 growth factors receptor	4915	reviewed	Kinase
Q5VZ30	BXGT015894	Glutamate decarboxylase 2 (Pancreatic islets and brain, 65kDa)	2572	unreviewed
Q8IVA8	BXGT018342	Glutamate decarboxylase 1 (Brain, 67kDa)	2571	unreviewed
Q8NER1	BXGT018556	Transient receptor potential cation channel subfamily V member 1	7442	reviewed	Ion channel
Q96EB6	BXGT019646	NAD-dependent protein deacetylase sirtuin-1	23411	reviewed	Epigenetic regulator
Q96P20	BXGT019704	NACHT, LRR and PYD domains-containing protein 3	114548	reviewed
Q99259	BXGT019915	Glutamate decarboxylase 1	2571	reviewed	Enzyme
Q99720	BXGT019955	Sigma non-opioid intracellular receptor 1	10280	reviewed
Q9NRA0	BXGT021183	Sphingosine kinase 2	56848	reviewed	Kinase
Q9NYX4	BXGT021263	Neuron-specific vesicular protein calcyon	50632	reviewed
Q9P0K1	BXGT021288	Disintegrin and metalloproteinase domain-containing protein 22	53616	reviewed	Enzyme
Q9P2R7	BXGT021304	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	8803	reviewed	Enzyme
Q9UIQ6	BXGT021721	Leucyl-cystinyl aminopeptidase	4012	reviewed	Enzyme
Q9UQ49	BXGT021805	Sialidase-3	10825	reviewed	Enzyme
Q9Y478	BXGT022271	5'-AMP-activated protein kinase subunit beta-1	5564	reviewed	Kinase
Q9Y5N1	BXGT022297	Histamine H3 receptor	11255	reviewed	G-protein coupled receptor
Q8IX03	BXGT024000	Protein KIBRA	23286	reviewed
P07320	BXGT026150	Gamma-crystallin D	1421	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}