adisease

Showing entry for Essential Tremor

General Disease Information
BXGD Id	BXGD006096
Disease Name	Essential Tremor
Disease CUI Id	C0270736
MeSH Codes	C10
Disease Class Name	Nervous System Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0000707
Human Phenotype Ontology Term	Abnormality of the nervous system
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
A8MPY1	BXGT001712	Gamma-aminobutyric acid receptor subunit rho-3	200959	reviewed	Ion channel
O00555	BXGT003936	Voltage-dependent P/Q-type calcium channel subunit alpha-1A	773	reviewed	Ion channel
O14578	BXGT004072	Citron Rho-interacting kinase	11113	reviewed	Kinase
O43464	BXGT004595	Serine protease HTRA2, mitochondrial	27429	reviewed
O43497	BXGT004596	Voltage-dependent T-type calcium channel subunit alpha-1G	8913	reviewed	Ion channel
O60260	BXGT004864	E3 ubiquitin-protein ligase parkin	5071	reviewed	Enzyme
O60741	BXGT004897	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1	348980	reviewed
O60760	BXGT004899	Hematopoietic prostaglandin D synthase	27306	reviewed
O75251	BXGT005107	NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial	374291	reviewed
P00325	BXGT005498	Alcohol dehydrogenase 1B	125	reviewed	Enzyme
P00441	BXGT005540	Superoxide dismutase [Cu-Zn]	6647	reviewed	Enzyme
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P04062	BXGT006140	Lysosomal acid glucosylceramidase	2629	reviewed
P08670	BXGT006810	Vimentin	7431	reviewed
P08842	BXGT006830	Steryl-sulfatase	412	reviewed	Enzyme
P09211	BXGT006869	Glutathione S-transferase P	2950	reviewed
P09601	BXGT006909	Heme oxygenase 1	3162	reviewed
P0DP23	BXGT007520	Calmodulin-1	808	reviewed
P0DP24	BXGT007521	Calmodulin-2	808	reviewed
P10632	BXGT007592	Cytochrome P450 2C8	1558	reviewed
P10635	BXGT007595	Cytochrome P450 2D6	1565	reviewed
P10636	BXGT007596	Microtubule-associated protein tau	4137	reviewed
P11712	BXGT007738	Cytochrome P450 2C9	1559	reviewed
P13716	BXGT007948	Delta-aminolevulinic acid dehydratase	210	reviewed	Enzyme
P14550	BXGT008019	Aldo-keto reductase family 1 member A1	10327	reviewed	Enzyme
P14867	BXGT008061	Gamma-aminobutyric acid receptor subunit alpha-1	2554	reviewed	Ion channel
P15529	BXGT008134	Membrane cofactor protein	4179	reviewed
P21554	BXGT008662	Cannabinoid receptor 1	1268	reviewed	G-protein coupled receptor
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P24046	BXGT008943	Gamma-aminobutyric acid receptor subunit rho-1	2569	reviewed	Ion channel
P27169	BXGT009161	Serum paraoxonase/arylesterase 1	5444	reviewed
P28476	BXGT009262	Gamma-aminobutyric acid receptor subunit rho-2	2570	reviewed	Ion channel
P30519	BXGT009429	Heme oxygenase 2	3163	reviewed
P33261	BXGT009707	Cytochrome P450 2C19	1557	reviewed
P35462	BXGT009835	D(3) dopamine receptor	1814	reviewed	G-protein coupled receptor
P35499	BXGT009839	Sodium channel protein type 4 subunit alpha	6329	reviewed	Ion channel
P35858	BXGT009876	Insulin-like growth factor-binding protein complex acid labile subunit	3483	reviewed	Receptor
P37840	BXGT010015	Alpha-synuclein	6622	reviewed	Transporter
P42898	BXGT010344	Methylenetetrahydrofolate reductase	4524	reviewed
P43003	BXGT010347	Excitatory amino acid transporter 1	6507	reviewed	Transporter
P43004	BXGT010348	Excitatory amino acid transporter 2	6506	reviewed	Transporter
P48169	BXGT010622	Gamma-aminobutyric acid receptor subunit alpha-4	2557	reviewed	Ion channel
P49903	BXGT010759	Selenide, water dikinase 1	22929	reviewed	Enzyme
P50135	BXGT010776	Histamine N-methyltransferase	3176	reviewed
P52788	BXGT010953	Spermine synthase	6611	reviewed
P62258	BXGT011415	14-3-3 protein epsilon	7531	reviewed	Chaperone
P78334	BXGT011834	Gamma-aminobutyric acid receptor subunit epsilon	2564	reviewed	Ion channel
P98164	BXGT012230	Low-density lipoprotein receptor-related protein 2	4036	reviewed
Q01726	BXGT012610	Melanocyte-stimulating hormone receptor	4157	reviewed	G-protein coupled receptor
Q01959	BXGT012624	Sodium-dependent dopamine transporter	6531	reviewed	Transporter
Q06787	BXGT012890	Synaptic functional regulator FMR1	2332	reviewed	Nucleic acid binding
Q16620	BXGT013645	BDNF/NT-3 growth factors receptor	4915	reviewed	Kinase
Q5S007	BXGT015650	Leucine-rich repeat serine/threonine-protein kinase 2	120892	reviewed	Kinase
Q6N021	BXGT016378	Methylcytosine dioxygenase TET2	54790	reviewed
Q96FE5	BXGT019657	Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1	84894	reviewed	Receptor
Q96QK1	BXGT019720	Vacuolar protein sorting-associated protein 35	55737	reviewed	Transporter
Q99523	BXGT019929	Sortilin	6272	reviewed	Transporter
Q99700	BXGT019949	Ataxin-2	6311	reviewed	Nucleic acid binding
Q9BZ23	BXGT020194	Pantothenate kinase 2, mitochondrial	80025	reviewed	Kinase
Q9BZR6	BXGT020202	Reticulon-4 receptor	65078	reviewed
Q9NP58	BXGT021143	ATP-binding cassette sub-family B member 6, mitochondrial	10058	reviewed	Transporter
Q9NY57	BXGT021250	Serine/threonine-protein kinase 32B	55351	reviewed	Kinase
Q9UBS5	BXGT021662	Gamma-aminobutyric acid type B receptor subunit 1	2550	reviewed	G-protein coupled receptor
Q9UI33	BXGT021712	Sodium channel protein type 11 subunit alpha	11280	reviewed	Ion channel
Q9UN88	BXGT021783	Gamma-aminobutyric acid receptor subunit theta	55879	reviewed	Ion channel
Q9UQD0	BXGT021811	Sodium channel protein type 8 subunit alpha	6334	reviewed	Ion channel
P0DP25	BXGT024595	Calmodulin-3	808	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}