Showing entry for Sodium channel protein type 11 subunit alpha


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT021712
Protein NameSodium channel protein type 11 subunit alpha
Uniport IdQ9UI33
GeneSCN11A
Gene Id11280
DomainIon_trans; Na_trans_assoc
Pfam PF00520   PF06512  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0086010 membrane depolarization during action potential
Biological Process GO:0019228 neuronal action potential
Biological Process GO:0034765 regulation of ion transmembrane transport
Biological Process GO:0051930 regulation of sensory perception of pain
Biological Process GO:0042493 response to drug
Biological Process GO:0035725 sodium ion transmembrane transport
Biological Process GO:0006814 sodium ion transport
molecular function GO:0005261 cation channel activity
molecular function GO:0005244 voltage-gated ion channel activity
molecular function GO:0005248 voltage-gated sodium channel activity
cellular component GO:0030424 axon
cellular component GO:0044299 C-fiber
cellular component GO:0070062 extracellular exosome
cellular component GO:0005886 plasma membrane
cellular component GO:0001518 voltage-gated sodium channel complex
Reactome
Pathway Id Pathway Name
R-HSA-1266738 Developmental Biology
R-HSA-373760 L1CAM interactions
R-HSA-397014 Muscle contraction
R-HSA-422475 Axon guidance
R-HSA-445095 Interaction between L1 and Ankyrins
R-HSA-5576891 Cardiac conduction
R-HSA-5576892 Phase 0 - rapid depolarisation
R-HSA-9675108 Nervous system development
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001973 BXGD000095 Alcoholic Intoxication, Chronic Chemically-Induced Disorders; Mental Disorders
C0002768 BXGD000128 Congenital Pain Insensitivity Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0005586 BXGD000315 Bipolar Disorder Mental Disorders
C0007766 BXGD000478 Intracranial Aneurysm Nervous System Diseases; Cardiovascular Diseases
C0009806 BXGD000633 Constipation Pathological Conditions, Signs and Symptoms
C0011991 BXGD000766 Diarrhea Pathological Conditions, Signs and Symptoms
C0013363 BXGD000818 Dysautonomia Nervous System Diseases
C0014175 BXGD000904 Endometriosis Female Urogenital Diseases and Pregnancy Complications
C0014805 BXGD000952 Primary Erythermalgia Cardiovascular Diseases
C0020075 BXGD001359 Hereditary Sensory Autonomic Neuropathy, Type 5 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0020429 BXGD001378 Hyperalgesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0020458 BXGD001393 Hyperhidrosis disorder Skin and Connective Tissue Diseases
C0020672 BXGD001461 Hypothermia, natural Pathological Conditions, Signs and Symptoms
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0023114 BXGD001610 Handedness
C0023418 BXGD001642 leukemia Neoplasms
C0027796 BXGD002037 Neuralgia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0030201 BXGD002194 Pain, Postoperative Pathological Conditions, Signs and Symptoms
C0033774 BXGD002419 Pruritus Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0033975 BXGD002447 Psychotic Disorders Mental Disorders
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0041834 BXGD002935 Erythema Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0042384 BXGD002979 Vasculitis Cardiovascular Diseases
C0085271 BXGD003148 Self-Injurious Behavior Behavior and Behavior Mechanisms
C0151786 BXGD003475 Muscle Weakness Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0151854 BXGD003487 Abnormal platelets Hemic and Lymphatic Diseases
C0233514 BXGD004584 Abnormal behavior Behavior and Behavior Mechanisms
C0270736 BXGD006096 Essential Tremor Nervous System Diseases
C0344307 BXGD007664 Absence of pain sensation Pathological Conditions, Signs and Symptoms; Mental Disorders
C0349204 BXGD007892 Nonorganic psychosis Mental Disorders
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0391976 BXGD008022 Pain Disorder Mental Disorders
C0442874 BXGD008814 Neuropathy Nervous System Diseases
C0458247 BXGD008904 Allodynia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0520947 BXGD009126 Clumsiness - motor delay Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0522254 BXGD009199 Analgesic Overuse Headache Nervous System Diseases
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0699739 BXGD009861 Sensory Neuropathy, Hereditary Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0751211 BXGD010350 Hyperalgesia, Primary Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0751212 BXGD010351 Hyperalgesia, Secondary Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0751213 BXGD010352 Tactile Allodynia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0751214 BXGD010353 Hyperalgesia, Thermal Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0751466 BXGD010452 Phonophobia Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0917799 BXGD011410 Hypersomnia Nervous System Diseases; Mental Disorders
C1611743 BXGD013456 Familial (FPAH)
C1720983 BXGD013698 Channelopathies Pathological Conditions, Signs and Symptoms
C1833661 BXGD013935 PAROXYSMAL EXTREME PAIN DISORDER Pathological Conditions, Signs and Symptoms
C1853926 BXGD015365 NONAKA MYOPATHY Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C1854301 BXGD015391 Motor delay Mental Disorders
C1855739 BXGD015538 Indifference to Pain, Congenital, Autosomal Recessive Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C2936719 BXGD018130 Mechanical Allodynia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C3276706 BXGD018694 Small Fiber Neuropathy Nervous System Diseases
C3806482 BXGD019514 Recurrent respiratory infections Infections; Respiratory Tract Diseases
C3809882 BXGD019618 NEUROPATHY, HEREDITARY SENSORY AND AUTONOMIC, TYPE VII
C3809899 BXGD019620 EPISODIC PAIN SYNDROME, FAMILIAL, 3 Pathological Conditions, Signs and Symptoms
C4721453 BXGD023744 Peripheral Nervous System Diseases Nervous System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0024988 Nifedipine 346.12
BXGC0049369 Tetrodotoxin 319.1
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein