Showing entry for Hyperalgesia, Thermal


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD010353
Disease NameHyperalgesia, Thermal
Disease CUI IdC0751214
MeSH Codes C23   C10  
Disease Class NamePathological Conditions, Signs and Symptoms; Nervous System Diseases
Semantic TypeSign or Symptom
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O14684 BXGT004082 Prostaglandin E synthase 9536 reviewed
O14842 BXGT004106 Free fatty acid receptor 1 2864 reviewed G-protein coupled receptor
O60741 BXGT004897 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 348980 reviewed
O60885 BXGT004906 Bromodomain-containing protein 4 23476 reviewed Epigenetic regulator
O75762 BXGT005151 Transient receptor potential cation channel subfamily A member 1 8989 reviewed Ion channel
O95180 BXGT005358 Voltage-dependent T-type calcium channel subunit alpha-1H 8912 reviewed Ion channel
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P01042 BXGT005722 Kininogen-1 3827 reviewed Enzyme modulator
P01100 BXGT005727 Proto-oncogene c-Fos 2353 reviewed Transcription factor
P01138 BXGT005738 Beta-nerve growth factor 4803 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P04049 BXGT006133 RAF proto-oncogene serine/threonine-protein kinase 5894 reviewed Kinase
P04150 BXGT006154 Glucocorticoid receptor 2908 reviewed Nuclear receptor
P05093 BXGT006313 Steroid 17-alpha-hydroxylase/17,20 lyase 1586 reviewed
P05107 BXGT006316 Integrin beta-2 3689 reviewed Receptor
P05129 BXGT006322 Protein kinase C gamma type 5582 reviewed Kinase
P05231 BXGT006345 Interleukin-6 3569 reviewed
P06213 BXGT006425 Insulin receptor 3643 reviewed Kinase
P06702 BXGT006476 Protein S100-A9 6280 reviewed Calcium-binding protein
P07204 BXGT006567 Thrombomodulin 7056 reviewed
P07550 BXGT006636 Beta-2 adrenergic receptor 154 reviewed G-protein coupled receptor
P08254 BXGT006758 Stromelysin-1 4314 reviewed Enzyme
P09429 BXGT006889 High mobility group protein B1 3146 reviewed Nucleic acid binding
P09486 BXGT006897 SPARC 6678 reviewed Signaling
P09917 BXGT006941 Arachidonate 5-lipoxygenase 240 reviewed Enzyme
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P11215 BXGT007672 Integrin alpha-M 3684 reviewed
P12429 BXGT007814 Annexin A3 306 reviewed
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P17301 BXGT008299 Integrin alpha-2 3673 reviewed
P17735 BXGT008335 Tyrosine aminotransferase 6898 reviewed
P18031 BXGT008369 Tyrosine-protein phosphatase non-receptor type 1 5770 reviewed
P18054 BXGT008370 Arachidonate 12-lipoxygenase, 12S-type 239 reviewed Enzyme
P21554 BXGT008662 Cannabinoid receptor 1 1268 reviewed G-protein coupled receptor
P21964 BXGT008714 Catechol O-methyltransferase 1312 reviewed Enzyme
P23219 BXGT008837 Prostaglandin G/H synthase 1 5742 reviewed Enzyme
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P25103 BXGT009020 Substance-P receptor 6869 reviewed G-protein coupled receptor
P26358 BXGT009104 DNA (cytosine-5)-methyltransferase 1 1786 reviewed Epigenetic regulator
P27361 BXGT009176 Mitogen-activated protein kinase 3 5595 reviewed Kinase
P28223 BXGT009239 5-hydroxytryptamine receptor 2A 3356 reviewed G-protein coupled receptor
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P29320 BXGT009332 Ephrin type-A receptor 3 2042 reviewed Kinase
P29475 BXGT009353 Nitric oxide synthase, brain 4842 reviewed
P30411 BXGT009424 B2 bradykinin receptor 624 reviewed G-protein coupled receptor
P32239 BXGT009612 Gastrin/cholecystokinin type B receptor 887 reviewed G-protein coupled receptor
P34972 BXGT009779 Cannabinoid receptor 2 1269 reviewed G-protein coupled receptor
P34998 BXGT009781 Corticotropin-releasing factor receptor 1 1394 reviewed
P35228 BXGT009800 Nitric oxide synthase, inducible 4843 reviewed
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35372 BXGT009823 Mu-type opioid receptor 4988 reviewed G-protein coupled receptor
P35462 BXGT009835 D(3) dopamine receptor 1814 reviewed G-protein coupled receptor
P35968 BXGT009887 Vascular endothelial growth factor receptor 2 3791 reviewed Kinase
P41231 BXGT010240 P2Y purinoceptor 2 5029 reviewed G-protein coupled receptor
P41240 BXGT010242 Tyrosine-protein kinase CSK 1445 reviewed Kinase
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P45983 BXGT010494 Mitogen-activated protein kinase 8 5599 reviewed Kinase
P45984 BXGT010495 Mitogen-activated protein kinase 9 5601 reviewed Kinase
P46663 BXGT010531 B1 bradykinin receptor 623 reviewed G-protein coupled receptor
P47900 BXGT010595 P2Y purinoceptor 1 5028 reviewed G-protein coupled receptor
P49116 BXGT010678 Nuclear receptor subfamily 2 group C member 2 7182 reviewed Nuclear receptor
P50897 BXGT010823 Palmitoyl-protein thioesterase 1 5538 reviewed Enzyme
P51575 BXGT010861 P2X purinoceptor 1 5023 reviewed Ion channel
P53041 BXGT010968 Serine/threonine-protein phosphatase 5 5536 reviewed
P54289 BXGT011040 Voltage-dependent calcium channel subunit alpha-2/delta-1 781 reviewed Ion channel
P54646 BXGT011062 5'-AMP-activated protein kinase catalytic subunit alpha-2 5563 reviewed Kinase
P55085 BXGT011104 Proteinase-activated receptor 2 2150 reviewed G-protein coupled receptor
P56373 BXGT011164 P2X purinoceptor 3 5024 reviewed Ion channel
Q00535 BXGT012534 Cyclin-dependent-like kinase 5 1020 reviewed Kinase
Q01726 BXGT012610 Melanocyte-stimulating hormone receptor 4157 reviewed G-protein coupled receptor
Q02083 BXGT012633 N-acylethanolamine-hydrolyzing acid amidase 27163 reviewed Enzyme
Q02156 BXGT012639 Protein kinase C epsilon type 5581 reviewed Kinase
Q05329 BXGT012814 Glutamate decarboxylase 2 2572 reviewed Enzyme
Q05513 BXGT012820 Protein kinase C zeta type 5590 reviewed Kinase
Q05586 BXGT012826 Glutamate receptor ionotropic, NMDA 1 2902 reviewed Ion channel
Q13131 BXGT013314 5'-AMP-activated protein kinase catalytic subunit alpha-1 5562 reviewed Kinase
Q13164 BXGT013322 Mitogen-activated protein kinase 7 5598 reviewed Kinase
Q13224 BXGT013328 Glutamate receptor ionotropic, NMDA 2B 2904 reviewed Ion channel
Q14624 BXGT013491 Inter-alpha-trypsin inhibitor heavy chain H4 3700 reviewed Enzyme modulator
Q15109 BXGT013537 Advanced glycosylation end product-specific receptor 177 reviewed Receptor
Q15910 BXGT013612 Histone-lysine N-methyltransferase EZH2 2146 reviewed Epigenetic regulator
Q16568 BXGT013640 Cocaine- and amphetamine-regulated transcript protein 9607 reviewed
Q5VZ30 BXGT015894 Glutamate decarboxylase 2 (Pancreatic islets and brain, 65kDa) 2572 unreviewed
Q7Z2W7 BXGT017248 Transient receptor potential cation channel subfamily M member 8 79054 reviewed Ion channel
Q86X55 BXGT017627 Histone-arginine methyltransferase CARM1 10498 reviewed Epigenetic regulator
Q8NER1 BXGT018556 Transient receptor potential cation channel subfamily V member 1 7442 reviewed Ion channel
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q99572 BXGT019935 P2X purinoceptor 7 5027 reviewed Ion channel
Q99720 BXGT019955 Sigma non-opioid intracellular receptor 1 10280 reviewed
Q9BR01 BXGT020115 Sulfotransferase 4A1 25830 reviewed
Q9H244 BXGT020448 P2Y purinoceptor 12 64805 reviewed G-protein coupled receptor
Q9H2X9 BXGT020459 Solute carrier family 12 member 5 57468 reviewed Transporter
Q9HBA0 BXGT020516 Transient receptor potential cation channel subfamily V member 4 59341 reviewed Ion channel
Q9P0U3 BXGT021292 Sentrin-specific protease 1 29843 reviewed Enzyme
Q9UBL9 BXGT021656 P2X purinoceptor 2 22953 reviewed Ion channel
Q9UHC3 BXGT021695 Acid-sensing ion channel 3 9311 reviewed Ion channel
Q9UI33 BXGT021712 Sodium channel protein type 11 subunit alpha 11280 reviewed Ion channel
Q9UQM7 BXGT021814 Calcium/calmodulin-dependent protein kinase type II subunit alpha 815 reviewed Kinase
Q9Y243 BXGT022214 RAC-gamma serine/threonine-protein kinase 10000 reviewed Kinase
Q9Y478 BXGT022271 5'-AMP-activated protein kinase subunit beta-1 5564 reviewed Kinase
Q9Y5Y9 BXGT022309 Sodium channel protein type 10 subunit alpha 6336 reviewed Ion channel
Q9Y6K1 BXGT022331 DNA (cytosine-5)-methyltransferase 3A 1788 reviewed
O95140 BXGT024482 Mitofusin-2 9927 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease