adisease

Showing entry for Motor delay

General Disease Information
BXGD Id	BXGD015391
Disease Name	Motor delay
Disease CUI Id	C1854301
MeSH Codes	F03
Disease Class Name	Mental Disorders
Semantic Type	Finding
Human Phenotype Ontology Id	HP:0000707
Human Phenotype Ontology Term	Abnormality of the nervous system
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
A4D126	BXGT001208	D-ribitol-5-phosphate cytidylyltransferase	729920	reviewed
O00142	BXGT003883	Thymidine kinase 2, mitochondrial	7084	reviewed	Kinase
O43766	BXGT004622	Lipoyl synthase, mitochondrial	11019	reviewed
O60313	BXGT004871	Dynamin-like 120 kDa protein, mitochondrial	4976	reviewed	Enzyme modulator
O60341	BXGT004873	Lysine-specific histone demethylase 1A	23028	reviewed	Epigenetic regulator
O75496	BXGT005132	Geminin	51053	reviewed
O75880	BXGT005158	Protein SCO1 homolog, mitochondrial	6341	reviewed	Enzyme
P00491	BXGT005555	Purine nucleoside phosphorylase	4860	reviewed	Enzyme
P00492	BXGT005556	Hypoxanthine-guanine phosphoribosyltransferase	3251	reviewed	Enzyme
P01111	BXGT005731	GTPase NRas	4893	reviewed	Enzyme modulator
P01308	BXGT005749	Insulin	3630	reviewed
P02458	BXGT005879	Collagen alpha-1(II) chain	1280	reviewed
P02545	BXGT005889	Prelamin-A/C	4000	reviewed
P02708	BXGT005927	Acetylcholine receptor subunit alpha	1134	reviewed	Ion channel
P04062	BXGT006140	Lysosomal acid glucosylceramidase	2629	reviewed
P04350	BXGT006193	Tubulin beta-4A chain	10382	reviewed	Cellular structure
P06753	BXGT006498	Tropomyosin alpha-3 chain	7170	reviewed	Cellular structure
P07101	BXGT006547	Tyrosine 3-monooxygenase	7054	reviewed
P07437	BXGT006624	Tubulin beta chain	203068	reviewed	Cellular structure
P08034	BXGT006716	Gap junction beta-1 protein	2705	reviewed	Cell-cell junction
P08069	BXGT006723	Insulin-like growth factor 1 receptor	3480	reviewed	Kinase
P09486	BXGT006897	SPARC	6678	reviewed	Signaling
P10253	BXGT007550	Lysosomal alpha-glucosidase	2548	reviewed	Enzyme
P11473	BXGT007709	Vitamin D3 receptor	7421	reviewed	Nuclear receptor
P13637	BXGT007933	Sodium/potassium-transporting ATPase subunit alpha-3	478	reviewed	Transporter
P14868	BXGT008062	Aspartate--tRNA ligase, cytoplasmic	1615	reviewed	Enzyme
P15311	BXGT008106	Ezrin	7430	reviewed	Cellular structure
P15735	BXGT008151	Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	5261	reviewed	Kinase
P15884	BXGT008166	Transcription factor 4	6925	reviewed	Transcription factor
P16473	BXGT008234	Thyrotropin receptor	7253	reviewed	G-protein coupled receptor
P19634	BXGT008504	Sodium/hydrogen exchanger 1	6548	reviewed	Transporter
P21333	BXGT008638	Filamin-A	2316	reviewed
P21802	BXGT008691	Fibroblast growth factor receptor 2	2263	reviewed	Kinase
P21817	BXGT008693	Ryanodine receptor 1	6261	reviewed	Ion channel
P22459	BXGT008773	Potassium voltage-gated channel subfamily A member 4	3739	reviewed	Ion channel
P22607	BXGT008784	Fibroblast growth factor receptor 3	2261	reviewed	Kinase
P23526	BXGT008878	Adenosylhomocysteinase	191	reviewed	Enzyme
P24752	BXGT008993	Acetyl-CoA acetyltransferase, mitochondrial	38	reviewed	Enzyme
P28329	BXGT009251	Choline O-acetyltransferase	1103	reviewed	Enzyme
P31040	BXGT009503	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial	6389	reviewed	Enzyme
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P35270	BXGT009807	Sepiapterin reductase	6697	reviewed
P35398	BXGT009825	Nuclear receptor ROR-alpha	6095	reviewed	Nuclear receptor
P35498	BXGT009838	Sodium channel protein type 1 subunit alpha	6323	reviewed	Ion channel
P35499	BXGT009839	Sodium channel protein type 4 subunit alpha	6329	reviewed	Ion channel
P35555	BXGT009845	Fibrillin-1	2200	reviewed	Calcium-binding protein
P35557	BXGT009846	Glucokinase	2645	reviewed	Kinase
P36894	BXGT009939	Bone morphogenetic protein receptor type-1A	657	reviewed	Kinase
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P41227	BXGT010238	N-alpha-acetyltransferase 10	8260	reviewed	Enzyme
P42263	BXGT010295	Glutamate receptor 3	2892	reviewed	Ion channel
P43003	BXGT010347	Excitatory amino acid transporter 1	6507	reviewed	Transporter
P43155	BXGT010363	Carnitine O-acetyltransferase	1384	reviewed	Enzyme
P45452	BXGT010462	Collagenase 3	4322	reviewed	Enzyme
P45954	BXGT010490	Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial	36	reviewed
P46019	BXGT010498	Phosphorylase b kinase regulatory subunit alpha, liver isoform	5256	reviewed	Kinase
P48029	BXGT010606	Sodium- and chloride-dependent creatine transporter 1	6535	reviewed	Transporter
P49591	BXGT010715	Serine--tRNA ligase, cytoplasmic	6301	reviewed	Enzyme
P49902	BXGT010758	Cytosolic purine 5'-nucleotidase	22978	reviewed	Enzyme
P50135	BXGT010776	Histamine N-methyltransferase	3176	reviewed
P51649	BXGT010872	Succinate-semialdehyde dehydrogenase, mitochondrial	7915	reviewed	Enzyme
P51800	BXGT010892	Chloride channel protein ClC-Ka	1187	reviewed	Ion channel
P51812	BXGT010893	Ribosomal protein S6 kinase alpha-3	6197	reviewed	Kinase
P54886	BXGT011092	Delta-1-pyrroline-5-carboxylate synthase	5832	reviewed	Enzyme
P60484	BXGT011307	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	5728	reviewed	Enzyme
P60880	BXGT011335	Synaptosomal-associated protein 25	6616	reviewed	Transporter
P60891	BXGT011337	Ribose-phosphate pyrophosphokinase 1	5631	reviewed	Kinase
P62266	BXGT011416	40S ribosomal protein S23	6228	reviewed	Nucleic acid binding
P63000	BXGT011481	Ras-related C3 botulinum toxin substrate 1	5879	reviewed	Enzyme modulator
P68133	BXGT011578	Actin, alpha skeletal muscle	58	reviewed	Cellular structure
Q01453	BXGT012588	Peripheral myelin protein 22	5376	reviewed	Cellular structure
Q02809	BXGT012674	Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1	5351	reviewed	Enzyme
Q03393	BXGT012711	6-pyruvoyl tetrahydrobiopterin synthase	5805	reviewed
Q04844	BXGT012789	Acetylcholine receptor subunit epsilon	1145	reviewed	Ion channel
Q06124	BXGT012856	Tyrosine-protein phosphatase non-receptor type 11	5781	reviewed
Q06210	BXGT012864	Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1	2673	reviewed	Enzyme
Q09428	BXGT013036	ATP-binding cassette sub-family C member 8	6833	reviewed	Transporter
Q09470	BXGT013037	Potassium voltage-gated channel subfamily A member 1	3736	reviewed	Ion channel
Q11203	BXGT013218	CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase	6487	reviewed
Q12882	BXGT013276	Dihydropyrimidine dehydrogenase [NADP(+)]	1806	reviewed	Enzyme
Q13002	BXGT013303	Glutamate receptor ionotropic, kainate 2	2898	reviewed	Ion channel
Q13153	BXGT013319	Serine/threonine-protein kinase PAK 1	5058	reviewed	Kinase
Q13224	BXGT013328	Glutamate receptor ionotropic, NMDA 2B	2904	reviewed	Ion channel
Q13255	BXGT013332	Metabotropic glutamate receptor 1	2911	reviewed	G-protein coupled receptor
Q13363	BXGT013344	C-terminal-binding protein 1	1487	reviewed	Transcription factor
Q13402	BXGT013348	Unconventional myosin-VIIa	4647	reviewed	Cellular structure
Q13510	BXGT013367	Acid ceramidase	427	reviewed	Enzyme
Q14003	BXGT013434	Potassium voltage-gated channel subfamily C member 3	3748	reviewed	Ion channel
Q14118	BXGT013444	Dystroglycan	1605	reviewed	Receptor
Q14204	BXGT013456	Cytoplasmic dynein 1 heavy chain 1	1778	reviewed	Enzyme
Q14643	BXGT013493	Inositol 1,4,5-trisphosphate receptor type 1	3708	reviewed	Ion channel
Q14654	BXGT013495	ATP-sensitive inward rectifier potassium channel 11	3767	reviewed	Ion channel
Q14671	BXGT013496	Pumilio homolog 1	9698	reviewed	Nucleic acid binding
Q15120	BXGT013542	[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial	5165	reviewed	Kinase
Q15149	BXGT013547	Plectin	5339	reviewed	Cellular structure
Q15233	BXGT013552	Non-POU domain-containing octamer-binding protein	4841	reviewed	Nucleic acid binding
Q15858	BXGT013610	Sodium channel protein type 9 subunit alpha	6335	reviewed	Ion channel
Q16836	BXGT013679	Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial	3033	reviewed
Q2M1P5	BXGT014129	Kinesin-like protein KIF7	374654	reviewed
Q5JPH6	BXGT015456	Probable glutamate--tRNA ligase, mitochondrial	124454	reviewed	Enzyme
Q6NVY1	BXGT016432	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial	26275	reviewed	Enzyme
Q6PI48	BXGT016471	Aspartate--tRNA ligase, mitochondrial	55157	reviewed	Enzyme
Q6VVX0	BXGT016585	Vitamin D 25-hydroxylase	120227	reviewed
Q71U36	BXGT016705	Tubulin alpha-1A chain	7846	reviewed	Cellular structure
Q86UE8	BXGT017612	Serine/threonine-protein kinase tousled-like 2	11011	reviewed	Kinase
Q8TBZ6	BXGT018792	tRNA methyltransferase 10 homolog A	93587	reviewed
Q8WVQ1	BXGT018996	Soluble calcium-activated nucleotidase 1	124583	reviewed
Q8WXF7	BXGT019011	Atlastin-1	51062	reviewed	Enzyme modulator
Q8WZ42	BXGT019023	Titin	7273	reviewed	Kinase
Q8WZA1	BXGT019024	Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1	55624	reviewed
Q92963	BXGT019401	GTP-binding protein Rit1	6016	reviewed	Enzyme modulator
Q96QU1	BXGT019721	Protocadherin-15	65217	reviewed
Q96SW2	BXGT019743	Protein cereblon	51185	reviewed	Enzyme
Q96T60	BXGT019745	Bifunctional polynucleotide phosphatase/kinase	11284	reviewed
Q9BPX6	BXGT020104	Calcium uptake protein 1, mitochondrial	10367	reviewed	Calcium-binding protein
Q9BVA1	BXGT020142	Tubulin beta-2B chain	347733	reviewed
Q9BXJ9	BXGT020170	N-alpha-acetyltransferase 15, NatA auxiliary subunit	80155	reviewed	Enzyme
Q9GZV3	BXGT020427	High affinity choline transporter 1	60482	reviewed	Transporter
Q9H1D0	BXGT020445	Transient receptor potential cation channel subfamily V member 6	55503	reviewed	Ion channel
Q9H3H5	BXGT020461	UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase	1798	reviewed	Enzyme
Q9H8P0	BXGT020497	Polyprenol reductase	79644	reviewed
Q9HBA0	BXGT020516	Transient receptor potential cation channel subfamily V member 4	59341	reviewed	Ion channel
Q9NSE4	BXGT021207	Isoleucine--tRNA ligase, mitochondrial	55699	reviewed	Enzyme
Q9NWM8	BXGT021233	Peptidyl-prolyl cis-trans isomerase FKBP14	55033	reviewed
Q9NYG8	BXGT021257	Potassium channel subfamily K member 4	50801	reviewed	Ion channel
Q9NYL2	BXGT021259	Mitogen-activated protein kinase kinase kinase 20	51776	reviewed	Kinase
Q9NZJ5	BXGT021275	Eukaryotic translation initiation factor 2-alpha kinase 3	9451	reviewed	Kinase
Q9UGL1	BXGT021685	Lysine-specific demethylase 5B	10765	reviewed	Epigenetic regulator
Q9UGM6	BXGT021687	Tryptophan--tRNA ligase, mitochondrial	10352	reviewed
Q9UI33	BXGT021712	Sodium channel protein type 11 subunit alpha	11280	reviewed	Ion channel
Q9UKE5	BXGT021741	TRAF2 and NCK-interacting protein kinase	23043	reviewed	Kinase
Q9UKM7	BXGT021747	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase	11253	reviewed	Chaperone
Q9UM47	BXGT021772	Neurogenic locus notch homolog protein 3	4854	reviewed
Q9UMX1	BXGT021778	Suppressor of fused homolog	51684	reviewed
Q9UQD0	BXGT021811	Sodium channel protein type 8 subunit alpha	6334	reviewed	Ion channel
Q9Y233	BXGT022210	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	10846	reviewed
Q9Y259	BXGT022219	Choline/ethanolamine kinase	1120	reviewed	Kinase
Q9Y4D7	BXGT022275	Plexin-D1	23129	reviewed
Q9Y6N9	BXGT022337	Harmonin	10083	reviewed	Cellular structure
Q96C86	BXGT022803	m7GpppX diphosphatase	28960	reviewed	Enzyme
Q53GS7	BXGT023762	Nucleoporin GLE1	2733	reviewed	Transporter
Q9H9S5	BXGT024623	Fukutin-related protein	79147	reviewed
Q13635	BXGT024910	Protein patched homolog 1	5727	reviewed
P51608	BXGT025073	Methyl-CpG-binding protein 2	4204	reviewed	Epigenetic regulator
Q05086	BXGT025648	Ubiquitin-protein ligase E3A	7337	reviewed
Q96MF2	BXGT025769	SH3 and cysteine-rich domain-containing protein 3	246329	reviewed
Q8TAB3	BXGT025819	Protocadherin-19	57526	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}