Showing entry for Congenital adrenal hyperplasia


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD000068
Disease NameCongenital adrenal hyperplasia
Disease CUI IdC0001627
MeSH Codes C16   C18   C13   C12   C19  
Disease Class NameCongenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id HP:0000818  
Human Phenotype Ontology TermAbnormality of the endocrine system
Disease Ontology Id DOID:0014667   DOID:630  
Disease Ontology Class Namedisease of metabolism; genetic disease
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00255 BXGT003903 Menin 4221 reviewed
O95263 BXGT005366 High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B 8622 reviewed
P00797 BXGT005658 Renin 5972 reviewed Enzyme
P01009 BXGT005714 Alpha-1-antitrypsin 5265 reviewed Enzyme modulator
P01189 BXGT005742 Pro-opiomelanocortin 5443 reviewed
P01215 BXGT005743 Glycoprotein hormones alpha chain 1081 reviewed
P01889 BXGT005809 HLA class I histocompatibility antigen, B-7 alpha chain 3106 reviewed
P01911 BXGT005816 HLA class II histocompatibility antigen, DRB1-15 beta chain 3123 reviewed Immune response
P04150 BXGT006154 Glucocorticoid receptor 2908 reviewed Nuclear receptor
P04275 BXGT006180 von Willebrand factor 7450 reviewed Enzyme modulator
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P05093 BXGT006313 Steroid 17-alpha-hydroxylase/17,20 lyase 1586 reviewed
P05108 BXGT006317 Cholesterol side-chain cleavage enzyme, mitochondrial 1583 reviewed
P06850 BXGT006511 Corticoliberin 1392 reviewed Signaling
P08686 BXGT006813 Steroid 21-hydroxylase 1589 reviewed
P0C0L4 BXGT007387 Complement C4-A 721 reviewed
P0C0L5 BXGT007388 Complement C4-B 721 reviewed
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10644 BXGT007597 cAMP-dependent protein kinase type I-alpha regulatory subunit 5573 reviewed
P11511 BXGT007717 Aromatase 1588 reviewed Enzyme
P14060 BXGT007978 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 3283 reviewed Enzyme
P15538 BXGT008137 Cytochrome P450 11B1, mitochondrial 1584 reviewed
P16435 BXGT008226 NADPH--cytochrome P450 reductase 5447 reviewed
P17612 BXGT008322 cAMP-dependent protein kinase catalytic subunit alpha 5566 reviewed Kinase
P19099 BXGT008456 Cytochrome P450 11B2, mitochondrial 1585 reviewed
P20813 BXGT008603 Cytochrome P450 2B6 1555 reviewed
P22694 BXGT008797 cAMP-dependent protein kinase catalytic subunit beta 5567 reviewed Kinase
P30518 BXGT009428 Vasopressin V2 receptor 554 reviewed G-protein coupled receptor
P33261 BXGT009707 Cytochrome P450 2C19 1557 reviewed
P37288 BXGT009977 Vasopressin V1a receptor 552 reviewed G-protein coupled receptor
P40926 BXGT010207 Malate dehydrogenase, mitochondrial 4191 reviewed Enzyme
P48544 BXGT010641 G protein-activated inward rectifier potassium channel 4 3762 reviewed Ion channel
P49748 BXGT010733 Very long-chain specific acyl-CoA dehydrogenase, mitochondrial 37 reviewed Enzyme
P51843 BXGT010897 Nuclear receptor subfamily 0 group B member 1 190 reviewed Nuclear receptor
P80365 BXGT011895 Corticosteroid 11-beta-dehydrogenase isozyme 2 3291 reviewed Enzyme
Q01668 BXGT012605 Voltage-dependent L-type calcium channel subunit alpha-1D 776 reviewed Ion channel
Q01718 BXGT012609 Adrenocorticotropic hormone receptor 4158 reviewed G-protein coupled receptor
Q04760 BXGT012782 Lactoylglutathione lyase 2739 reviewed
Q06520 BXGT012880 Bile salt sulfotransferase 6822 reviewed
Q07075 BXGT012917 Glutamyl aminopeptidase 2028 reviewed Enzyme
Q13427 BXGT013354 Peptidyl-prolyl cis-trans isomerase G 9360 reviewed
Q13639 BXGT013389 5-hydroxytryptamine receptor 4 3360 reviewed G-protein coupled receptor
Q14451 BXGT013471 Growth factor receptor-bound protein 7 2886 reviewed Receptor
Q16874 BXGT013685 Cytochrome P450 21-hydroxylase 1589 unreviewed
Q9H251 BXGT020449 Cadherin-23 64072 reviewed
Q9HCR9 BXGT020537 Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A 50940 reviewed
P04439 BXGT022649 HLA class I histocompatibility antigen, A-3 alpha chain 3105 reviewed
P24462 BXGT022674 Cytochrome P450 3A7 1551 reviewed
P35670 BXGT023695 Copper-transporting ATPase 2 540 reviewed Transporter
P07954 BXGT023939 Fumarate hydratase, mitochondrial 2271 reviewed Enzyme
P07320 BXGT026150 Gamma-crystallin D 1421 reviewed
Q08477 BXGT026164 Docosahexaenoic acid omega-hydroxylase CYP4F3 4051 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease