acompound

Showing entry for Carbanilide

General Compound Information
BXGC Id	BXGC0004580
Compound Name	Carbanilide
Structure
Formula	C13H12N2O
InchiKey	GWEHVDNNLFDJLR-UHFFFAOYSA-N
SMILES	O=C(NC1=CC=CC=C1)NC1=CC=CC=C1
Inchi	InChI=1S/C13H12N2O/c16-13(14-11-7-3-1-4-8-11)15-12-9-5-2-6-10-12/h1-10H,(H2,14,15,16)
IUPAC	1,3-diphenylurea
Molecular Weight	212.25
Pubchem Id	7595
Chembl Id	CHEMBL354676

Targets of Information Source

DrugBank

DB07496

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
P95276	BXGT012152	Epoxide hydrolase B	reviewed	-	MT1988	experimental	-

PDB

BSU

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
P95276	BXGT012152	Epoxide hydrolase B	reviewed	MT1988	-	-	19	-	-
Q9LLQ2	BXGT021079	Class 10 plant pathogenesis-related protein 2B	reviewed	PR10.2B	-	-	-	4200	-
P34913	BXGT009770	Bifunctional epoxide hydrolase 2	reviewed	EPHX2	Enzyme	-	93	-	-
G7CF24	BXGT003537	Putative epoxide hydrolase EPHA	unreviewed	KEK_07967	-	-	-	-	-

Binding DB

25725

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT012152	Epoxide hydrolase B	reviewed		MT1988	-	19	-	-
reviewed	BXGT010386	Tyrosine-protein kinase SYK	reviewed	Kinase	SYK	-	>660000	-	-
reviewed	BXGT009770	Bifunctional epoxide hydrolase 2	reviewed	Enzyme	EPHX2	-	390	-	-
reviewed	BXGT009770	Bifunctional epoxide hydrolase 2	reviewed	Enzyme	EPHX2	-	400	-	-

CHEMBL

CHEMBL354676

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
Q9HAZ1	BXGT020511	Dual specificity protein kinase CLK4	reviewed	-	CLK4	Ki	'='	7943	nM
P07333	BXGT006602	Macrophage colony-stimulating factor 1 receptor	reviewed	Kinase	CSF1R	Ki	'>'	63095	nM
O00444	BXGT003921	Serine/threonine-protein kinase PLK4	reviewed	Kinase	PLK4	Ki	'>'	39810	nM
P07099	BXGT006546	Epoxide hydrolase 1	reviewed	-	EPHX1	IC50	'='	1200	nM
Q9Y6L6	BXGT022334	Solute carrier organic anion transporter family member 1B1	reviewed	Transporter	SLCO1B1	Inhibition	'='	86	%
Q9NUW8	BXGT021219	Tyrosyl-DNA phosphodiesterase 1	reviewed	Enzyme	TDP1	Potency	-	18356	nM
P16473	BXGT008234	Thyrotropin receptor	reviewed	G-protein coupled receptor	TSHR	Potency	'='	39810	nM
Q15118	BXGT013540	[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial	reviewed	Kinase	PDK1	Inhibition	'='	20	%
P11309	BXGT007685	Serine/threonine-protein kinase pim-1	reviewed	Kinase	PIM1	Ki	'>'	63095	nM
Q9NUW8	BXGT021219	Tyrosyl-DNA phosphodiesterase 1	reviewed	Enzyme	TDP1	Potency	-	14581	nM
P09619	BXGT006911	Platelet-derived growth factor receptor beta	reviewed	Kinase	PDGFRB	Ki	'>'	79432	nM
P10275	BXGT007552	Androgen receptor	reviewed	Nuclear receptor	AR	Potency	-	44668	nM
Q08881	BXGT013012	Tyrosine-protein kinase ITK/TSK	reviewed	Kinase	ITK	Inhibition	'='	0	%
Q13177	BXGT013323	Serine/threonine-protein kinase PAK 2	reviewed	Kinase	PAK2	Inhibition	'='	5	%
P43405	BXGT010386	Tyrosine-protein kinase SYK	reviewed	Kinase	SYK	Inhibition	'='	87	%
P43405	BXGT010386	Tyrosine-protein kinase SYK	reviewed	Kinase	SYK	IC50	'>'	660000	nM
Q13464	BXGT013357	Rho-associated protein kinase 1	reviewed	Kinase	ROCK1	Inhibition	'='	5	%
P51449	BXGT010846	Nuclear receptor ROR-gamma	reviewed	Nuclear receptor	RORC	Potency	-	841	nM
P04637	BXGT006243	Cellular tumor antigen p53	reviewed	Transcription factor	TP53	Potency	'='	5011	nM
Q16539	BXGT013634	Mitogen-activated protein kinase 14	reviewed	Kinase	MAPK14	Inhibition	'='	53	%
P34913	BXGT009770	Bifunctional epoxide hydrolase 2	reviewed	Enzyme	EPHX2	IC50	'='	390	nM
P35968	BXGT009887	Vascular endothelial growth factor receptor 2	reviewed	Kinase	KDR	Ki	'>'	100000	nM
P35869	BXGT009877	Aryl hydrocarbon receptor	reviewed	Transcription factor	AHR	Potency	-	12589	nM
Q8IU85	BXGT018333	Calcium/calmodulin-dependent protein kinase type 1D	reviewed	Kinase	CAMK1D	Ki	'>'	100000	nM
Q94696	BXGT019553	Luciferase	unreviewed	-	luc	Potency	'='	11220	nM
Q16637	BXGT013646	Survival motor neuron protein	reviewed	Epigenetic regulator	SMN1	Potency	'='	17782	nM
P48736	BXGT010658	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	reviewed	Kinase	PIK3CG	Inhibition	'='	9	%
P49841	BXGT010750	Glycogen synthase kinase-3 beta	reviewed	Kinase	GSK3B	Inhibition	'='	11	%
O14965	BXGT004117	Aurora kinase A	reviewed	Kinase	AURKA	Inhibition	'='	0	%
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	reviewed	Enzyme	NFE2L2	Potency	-	4730	nM
Q9NPD5	BXGT021151	Solute carrier organic anion transporter family member 1B3	reviewed	Transporter	SLCO1B3	Inhibition	'='	104	%
P04626	BXGT006238	Receptor tyrosine-protein kinase erbB-2	reviewed	Kinase	ERBB2	Inhibition	'='	2	%
P11309	BXGT007685	Serine/threonine-protein kinase pim-1	reviewed	Kinase	PIM1	Inhibition	'='	12	%
Q04759	BXGT012781	Protein kinase C theta type	reviewed	Kinase	PRKCQ	Ki	'>'	100000	nM
O14757	BXGT004092	Serine/threonine-protein kinase Chk1	reviewed	Kinase	CHEK1	Ki	'>'	50118	nM
P95276	BXGT012152	Epoxide hydrolase B	reviewed	-	MT1988	IC50	'='	19	nM
Q05397	BXGT012815	Focal adhesion kinase 1	reviewed	Kinase	PTK2	Inhibition	'='	30	%
O94782	BXGT005332	Ubiquitin carboxyl-terminal hydrolase 1	reviewed	Enzyme	USP1	Potency	-	1258	nM
P0A0J7	BXGT006970	Quinolone resistance protein NorA	reviewed	-	norA	Inhibition	'='	20	%
P15056	BXGT008075	Serine/threonine-protein kinase B-raf	reviewed	Kinase	BRAF	Inhibition	'='	8	%
P49137	BXGT010680	MAP kinase-activated protein kinase 2	reviewed	Kinase	MAPKAPK2	Inhibition	'='	18	%
O75496	BXGT005132	Geminin	reviewed	-	GMNN	Potency	-	730	nM
P50750	BXGT010818	Cyclin-dependent kinase 9	reviewed	Kinase	CDK9	Ki	'='	3981	nM
P51450	BXGT010847	Nuclear receptor ROR-gamma	reviewed	-	Rorc	Potency	'='	3548	nM
Q96GD4	BXGT019667	Aurora kinase B	reviewed	Kinase	AURKB	Inhibition	'='	30	%
P52333	BXGT010928	Tyrosine-protein kinase JAK3	reviewed	Kinase	JAK3	Inhibition	'='	0	%
P45983	BXGT010494	Mitogen-activated protein kinase 8	reviewed	Kinase	MAPK8	Inhibition	'='	0	%
P06213	BXGT006425	Insulin receptor	reviewed	Kinase	INSR	Ki	'>'	50118	nM
P04150	BXGT006154	Glucocorticoid receptor	reviewed	Nuclear receptor	NR3C1	Potency	-	50118	nM
Q57TT1	BXGT015153	Uncharacterized protein	unreviewed	-	Tb927.8.6820	Potency	-	28183	nM
P53350	BXGT010984	Serine/threonine-protein kinase PLK1	reviewed	Kinase	PLK1	Ki	'>'	50118	nM
P04637	BXGT006243	Cellular tumor antigen p53	reviewed	Transcription factor	TP53	Potency	'='	10000	nM
Q16637	BXGT013646	Survival motor neuron protein	reviewed	Epigenetic regulator	SMN1	Potency	'='	7943	nM
P31749	BXGT009574	RAC-alpha serine/threonine-protein kinase	reviewed	Kinase	AKT1	Inhibition	'='	11	%
O00329	BXGT003909	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	reviewed	Kinase	PIK3CD	Inhibition	'='	11	%
O14920	BXGT004110	Inhibitor of nuclear factor kappa-B kinase subunit beta	reviewed	Kinase	IKBKB	Inhibition	'='	0	%
O00141	BXGT003882	Serine/threonine-protein kinase Sgk1	reviewed	Kinase	SGK1	Inhibition	'='	15	%
Q86V86	BXGT017617	Serine/threonine-protein kinase pim-3	reviewed	-	PIM3	Ki	'>'	79432	nM
Q13627	BXGT013385	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	reviewed	Kinase	DYRK1A	Ki	'>'	79432	nM
O43353	BXGT004589	Receptor-interacting serine/threonine-protein kinase 2	reviewed	Kinase	RIPK2	Inhibition	'='	0	%
Q9R1A7	BXGT021413	Nuclear receptor subfamily 1 group I member 2	reviewed	-	Nr1i2	Potency	-	39810	nM
P00533	BXGT005575	Epidermal growth factor receptor	reviewed	Kinase	EGFR	Inhibition	'='	0	%
P31751	BXGT009576	RAC-beta serine/threonine-protein kinase	reviewed	Kinase	AKT2	Inhibition	'='	16	%
Q99683	BXGT019947	Mitogen-activated protein kinase kinase kinase 5	reviewed	Kinase	MAP3K5	Inhibition	'='	8	%
Q9Y243	BXGT022214	RAC-gamma serine/threonine-protein kinase	reviewed	Kinase	AKT3	Ki	'>'	63095	nM
P31749	BXGT009574	RAC-alpha serine/threonine-protein kinase	reviewed	Kinase	AKT1	Ki	'>'	50118	nM
O14965	BXGT004117	Aurora kinase A	reviewed	Kinase	AURKA	Ki	'>'	39810	nM
Q9H4B4	BXGT020474	Serine/threonine-protein kinase PLK3	reviewed	Kinase	PLK3	Ki	'>'	50118	nM
P08069	BXGT006723	Insulin-like growth factor 1 receptor	reviewed	Kinase	IGF1R	Inhibition	'='	6	%
Q15303	BXGT013557	Receptor tyrosine-protein kinase erbB-4	reviewed	Kinase	ERBB4	Inhibition	'='	0	%
P07332	BXGT006601	Tyrosine-protein kinase Fes/Fps	reviewed	Kinase	FES	Inhibition	'='	13	%
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	reviewed	Kinase	PIK3CA	Inhibition	'='	11	%
P31751	BXGT009576	RAC-beta serine/threonine-protein kinase	reviewed	Kinase	AKT2	Ki	'>'	50118	nM
P34913	BXGT009770	Bifunctional epoxide hydrolase 2	reviewed	Enzyme	EPHX2	IC50	'='	400	nM
P38398	BXGT010037	Breast cancer type 1 susceptibility protein	reviewed	Enzyme	BRCA1	Potency	-	15848	nM
Q03431	BXGT012714	Parathyroid hormone/parathyroid hormone-related peptide receptor	reviewed	G-protein coupled receptor	PTH1R	Potency	-	50118	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00823	Fruits		Fruits

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}