Showing entry for Osteoporosis, Age-Related


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD000076
Disease NameOsteoporosis, Age-Related
Disease CUI IdC0001787
MeSH Codes C18   C05  
Disease Class NameNutritional and Metabolic Diseases; Musculoskeletal Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O14788 BXGT004100 Tumor necrosis factor ligand superfamily member 11 8600 reviewed Signaling
O95622 BXGT005386 Adenylate cyclase type 5 111 reviewed
P00491 BXGT005555 Purine nucleoside phosphorylase 4860 reviewed Enzyme
P00797 BXGT005658 Renin 5972 reviewed Enzyme
P00918 BXGT005690 Carbonic anhydrase 2 760 reviewed
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01189 BXGT005742 Pro-opiomelanocortin 5443 reviewed
P01270 BXGT005746 Parathyroid hormone 5741 reviewed
P02452 BXGT005878 Collagen alpha-1(I) chain 1277 reviewed
P02545 BXGT005889 Prelamin-A/C 4000 reviewed
P02671 BXGT005914 Fibrinogen alpha chain 2243 reviewed
P02675 BXGT005916 Fibrinogen beta chain 2244 reviewed Signaling
P02788 BXGT005963 Lactotransferrin 4057 reviewed Enzyme
P04179 BXGT006163 Superoxide dismutase [Mn], mitochondrial 6648 reviewed Enzyme
P04278 BXGT006182 Sex hormone-binding globulin 6462 reviewed
P04406 BXGT006207 Glyceraldehyde-3-phosphate dehydrogenase 2597 reviewed Enzyme
P05186 BXGT006338 Alkaline phosphatase, tissue-nonspecific isozyme 249 reviewed Enzyme
P05231 BXGT006345 Interleukin-6 3569 reviewed
P06396 BXGT006435 Gelsolin 2934 reviewed Cellular structure
P06733 BXGT006490 Alpha-enolase 2023 reviewed Enzyme
P07203 BXGT006566 Glutathione peroxidase 1 2876 reviewed Enzyme
P07237 BXGT006576 Protein disulfide-isomerase 5034 reviewed
P07355 BXGT006609 Annexin A2 302 reviewed
P08887 BXGT006835 Interleukin-6 receptor subunit alpha 3570 reviewed Signaling
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P11473 BXGT007709 Vitamin D3 receptor 7421 reviewed Nuclear receptor
P11511 BXGT007717 Aromatase 1588 reviewed Enzyme
P14618 BXGT008027 Pyruvate kinase PKM 5315 reviewed Kinase
P18206 BXGT008389 Vinculin 7414 reviewed
P21554 BXGT008662 Cannabinoid receptor 1 1268 reviewed G-protein coupled receptor
P25787 BXGT009069 Proteasome subunit alpha type-2 5683 reviewed
P28066 BXGT009227 Proteasome subunit alpha type-5 5686 reviewed
P28845 BXGT009297 Corticosteroid 11-beta-dehydrogenase isozyme 1 3290 reviewed
P30988 BXGT009491 Calcitonin receptor 799 reviewed G-protein coupled receptor
P31939 BXGT009584 Bifunctional purine biosynthesis protein PURH 471 reviewed Enzyme
P34972 BXGT009779 Cannabinoid receptor 2 1269 reviewed G-protein coupled receptor
P42224 BXGT010286 Signal transducer and activator of transcription 1-alpha/beta 6772 reviewed Nucleic acid binding
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P48735 BXGT010657 Isocitrate dehydrogenase [NADP], mitochondrial 3418 reviewed
P49768 BXGT010740 Presenilin-1 5663 reviewed Enzyme
P49810 BXGT010747 Presenilin-2 5664 reviewed Enzyme
P50479 BXGT010804 PDZ and LIM domain protein 4 8572 reviewed Cellular structure
P55809 BXGT011127 Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial 5019 reviewed Enzyme
P58335 BXGT011233 Anthrax toxin receptor 2 118429 reviewed Receptor
P60174 BXGT011294 Triosephosphate isomerase 7167 reviewed Enzyme
P63261 BXGT011512 Actin, cytoplasmic 2 71 reviewed Cellular structure
P67936 BXGT011570 Tropomyosin alpha-4 chain 7171 reviewed Cellular structure
P68363 BXGT011594 Tubulin alpha-1B chain 10376 reviewed Cellular structure
Q00987 BXGT012559 E3 ubiquitin-protein ligase Mdm2 4193 reviewed Nucleic acid binding
Q01081 BXGT012566 Splicing factor U2AF 35 kDa subunit 7307 reviewed
Q07973 BXGT012952 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 1591 reviewed Enzyme
Q2MKA7 BXGT014140 R-spondin-1 284654 reviewed
Q99497 BXGT019926 Protein/nucleic acid deglycase DJ-1 11315 reviewed Enzyme
Q99685 BXGT019948 Monoglyceride lipase 11343 reviewed Enzyme
Q9HCE7 BXGT020532 E3 ubiquitin-protein ligase SMURF1 57154 reviewed Enzyme
P08123 BXGT024477 Collagen alpha-2(I) chain 1278 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease