adisease

Showing entry for Goiter

General Disease Information
BXGD Id	BXGD001162
Disease Name	Goiter
Disease CUI Id	C0018021
MeSH Codes	C19
Disease Class Name	Endocrine System Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0000818
Human Phenotype Ontology Term	Abnormality of the endocrine system
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O14746	BXGT004091	Telomerase reverse transcriptase	7015	reviewed	Enzyme
O14924	BXGT004111	Regulator of G-protein signaling 12	6002	reviewed
O15178	BXGT004135	T-box transcription factor T	6862	reviewed	Transcription factor
O15553	BXGT004181	Pyrin	4210	reviewed
O60271	BXGT004866	C-Jun-amino-terminal kinase-interacting protein 4	9043	reviewed	Enzyme modulator
O75874	BXGT005157	Isocitrate dehydrogenase [NADP] cytoplasmic	3417	reviewed
P00338	BXGT005504	L-lactate dehydrogenase A chain	3939	reviewed	Enzyme
P00740	BXGT005634	Coagulation factor IX	2158	reviewed	Enzyme
P01270	BXGT005746	Parathyroid hormone	5741	reviewed
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P03372	BXGT006059	Estrogen receptor	2099	reviewed	Nuclear receptor
P03886	BXGT006108	NADH-ubiquinone oxidoreductase chain 1	4535	reviewed	Enzyme
P03905	BXGT006113	NADH-ubiquinone oxidoreductase chain 4	4538	reviewed	Enzyme
P03915	BXGT006114	NADH-ubiquinone oxidoreductase chain 5	4540	reviewed	Enzyme
P03923	BXGT006115	NADH-ubiquinone oxidoreductase chain 6	4541	reviewed
P04054	BXGT006136	Phospholipase A2	5319	reviewed	Enzyme
P04629	BXGT006239	High affinity nerve growth factor receptor	4914	reviewed	Kinase
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P04731	BXGT006251	Metallothionein-1A	4489	reviewed
P05187	BXGT006339	Alkaline phosphatase, placental type	250	reviewed	Enzyme
P05231	BXGT006345	Interleukin-6	3569	reviewed
P06396	BXGT006435	Gelsolin	2934	reviewed	Cellular structure
P06454	BXGT006441	Prothymosin alpha	5757	reviewed
P06731	BXGT006488	Carcinoembryonic antigen-related cell adhesion molecule 5	1048	reviewed
P07202	BXGT006565	Thyroid peroxidase	7173	reviewed	Enzyme
P07949	BXGT006703	Proto-oncogene tyrosine-protein kinase receptor Ret	5979	reviewed	Kinase
P08253	BXGT006757	72 kDa type IV collagenase	4313	reviewed	Enzyme
P10828	BXGT007624	Thyroid hormone receptor beta	7068	reviewed	Nuclear receptor
P11166	BXGT007661	Solute carrier family 2, facilitated glucose transporter member 1	6513	reviewed	Transporter
P11362	BXGT007693	Fibroblast growth factor receptor 1	2260	reviewed	Kinase
P12235	BXGT007774	ADP/ATP translocase 1	291	reviewed	Transporter
P14618	BXGT008027	Pyruvate kinase PKM	5315	reviewed	Kinase
P15056	BXGT008075	Serine/threonine-protein kinase B-raf	673	reviewed	Kinase
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P16442	BXGT008227	Histo-blood group ABO system transferase	28	reviewed	Enzyme
P16455	BXGT008229	Methylated-DNA--protein-cysteine methyltransferase	4255	reviewed
P16473	BXGT008234	Thyrotropin receptor	7253	reviewed	G-protein coupled receptor
P17948	BXGT008358	Vascular endothelial growth factor receptor 1	2321	reviewed	Kinase
P24385	BXGT008965	G1/S-specific cyclin-D1	595	reviewed	Enzyme modulator
P24593	BXGT008979	Insulin-like growth factor-binding protein 5	3488	reviewed	Enzyme modulator
P27037	BXGT009153	Activin receptor type-2A	92	reviewed	Kinase
P27487	BXGT009187	Dipeptidyl peptidase 4	1803	reviewed	Enzyme
P27708	BXGT009202	CAD protein	790	reviewed	Enzyme
P30044	BXGT009395	Peroxiredoxin-5, mitochondrial	25824	reviewed
P31749	BXGT009574	RAC-alpha serine/threonine-protein kinase	207	reviewed	Kinase
P35968	BXGT009887	Vascular endothelial growth factor receptor 2	3791	reviewed	Kinase
P36896	BXGT009940	Activin receptor type-1B	91	reviewed	Kinase
P41222	BXGT010237	Prostaglandin-H2 D-isomerase	5730	reviewed	Enzyme
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P46527	BXGT010525	Cyclin-dependent kinase inhibitor 1B	1027	reviewed
P48735	BXGT010657	Isocitrate dehydrogenase [NADP], mitochondrial	3418	reviewed
P51795	BXGT010891	H(+)/Cl(-) exchange transporter 5	1184	reviewed	Ion channel
P54098	BXGT011030	DNA polymerase subunit gamma-1	5428	reviewed	Enzyme
P60484	BXGT011307	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	5728	reviewed	Enzyme
P60568	BXGT011315	Interleukin-2	3558	reviewed
P63092	BXGT011495	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	2778	reviewed
P78508	BXGT011845	ATP-sensitive inward rectifier potassium channel 10	3766	reviewed	Ion channel
Q02763	BXGT012667	Angiopoietin-1 receptor	7010	reviewed	Kinase
Q06710	BXGT012887	Paired box protein Pax-8	7849	reviewed
Q07812	BXGT012940	Apoptosis regulator BAX	581	reviewed	Signaling
Q13698	BXGT013392	Voltage-dependent L-type calcium channel subunit alpha-1S	779	reviewed	Ion channel
Q14002	BXGT013433	Carcinoembryonic antigen-related cell adhesion molecule 7	1087	reviewed
Q14145	BXGT013448	Kelch-like ECH-associated protein 1	9817	reviewed
Q15389	BXGT013564	Angiopoietin-1	284	reviewed	Signaling
Q7L266	BXGT016993	Isoaspartyl peptidase/L-asparaginase	80150	reviewed	Enzyme
Q7LG56	BXGT016999	Ribonucleoside-diphosphate reductase subunit M2 B	50484	reviewed	Enzyme
Q92731	BXGT019366	Estrogen receptor beta	2100	reviewed	Nuclear receptor
Q99828	BXGT019967	Calcium and integrin-binding protein 1	10519	reviewed
Q9H0A0	BXGT020434	RNA cytidine acetyltransferase	55226	reviewed
Q9H251	BXGT020449	Cadherin-23	64072	reviewed
Q9NPH5	BXGT021159	NADPH oxidase 4	50507	reviewed	Enzyme
Q9NYB5	BXGT021255	Solute carrier organic anion transporter family member 1C1	53919	reviewed	Transporter
Q9UPY3	BXGT021802	Endoribonuclease Dicer	23405	reviewed	Enzyme
Q92911	BXGT022650	Sodium/iodide cotransporter	6528	reviewed	Transporter
P00395	BXGT023596	Cytochrome c oxidase subunit 1	4512	reviewed	Enzyme
P40198	BXGT023750	Carcinoembryonic antigen-related cell adhesion molecule 3	1084	reviewed
Q13635	BXGT024910	Protein patched homolog 1	5727	reviewed
P00403	BXGT026137	Cytochrome c oxidase subunit 2	4513	reviewed	Enzyme
V9HWB9	BXGT026149	L-lactate dehydrogenase	3939	unreviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}