protein

Showing entry for RNA binding protein fox-1 homolog 1

General Target Information
BXGT Id	BXGT021231
Protein Name	RNA binding protein fox-1 homolog 1
Uniport Id	Q9NWB1
Gene	RBFOX1
Gene Id	54715
Domain	Fox-1_C; RRM_1
Pfam	PF12414 PF00076
Organism	Homo sapiens (Human)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0006397	mRNA processing
Biological Process	GO:0007399	nervous system development
Biological Process	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
Biological Process	GO:0008380	RNA splicing
Biological Process	GO:0050658	RNA transport
molecular function	GO:0003729	mRNA binding
molecular function	GO:0008022	protein C-terminus binding
molecular function	GO:0003723	RNA binding
cellular component	GO:0005737	cytoplasm
cellular component	GO:0010494	cytoplasmic stress granule
cellular component	GO:0097165	nuclear stress granule
cellular component	GO:0005634	nucleus
cellular component	GO:0005802	trans-Golgi network

Reactome

Pathway Id	Pathway Name
R-HSA-212436	Generic Transcription Pathway
R-HSA-73857	RNA Polymerase II Transcription
R-HSA-74160	Gene expression (Transcription)
R-HSA-8986944	Transcriptional Regulation by MECP2
R-HSA-9022707	MECP2 regulates transcription factors

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class
C0002395	BXGD000111	Alzheimer's Disease	Nervous System Diseases; Mental Disorders
C0003467	BXGD000194	Anxiety	Behavior and Behavior Mechanisms
C0003868	BXGD000233	Arthritis, Gouty	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0003873	BXGD000236	Rheumatoid Arthritis	Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004352	BXGD000269	Autistic Disorder	Mental Disorders
C0005411	BXGD000313	Biliary Atresia	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases
C0007097	BXGD000424	Carcinoma	Neoplasms
C0008312	BXGD000527	Primary biliary cirrhosis	Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0009402	BXGD000605	Colorectal Carcinoma	Digestive System Diseases; Neoplasms
C0011884	BXGD000762	Diabetic Retinopathy	Eye Diseases; Endocrine System Diseases; Cardiovascular Diseases
C0013080	BXGD000797	Down Syndrome	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0014175	BXGD000904	Endometriosis	Female Urogenital Diseases and Pregnancy Complications
C0014544	BXGD000926	Epilepsy	Nervous System Diseases
C0014547	BXGD000927	Epilepsies, Partial	Nervous System Diseases
C0014548	BXGD000928	Epilepsy, Generalized	Nervous System Diseases
C0014556	BXGD000932	Epilepsy, Temporal Lobe	Nervous System Diseases
C0017601	BXGD001125	Glaucoma	Eye Diseases
C0018099	BXGD001172	Gout	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0018801	BXGD001226	Heart failure	Cardiovascular Diseases
C0018802	BXGD001227	Congestive heart failure	Cardiovascular Diseases
C0018810	BXGD001231	heart rate
C0019100	BXGD001283	Severe Dengue	Infections
C0019163	BXGD001295	Hepatitis B	Digestive System Diseases; Infections
C0020459	BXGD001394	Hyperinsulinism	Nutritional and Metabolic Diseases
C0020490	BXGD001403	Hyperopia	Eye Diseases
C0021704	BXGD001510	Intelligence	Behavior and Behavior Mechanisms
C0022333	BXGD001534	Jacksonian Seizure	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0025362	BXGD001866	Mental Retardation	Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0027092	BXGD001971	Myopia	Eye Diseases
C0027126	BXGD001976	Myotonic Dystrophy	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0027404	BXGD001984	Narcolepsy	Nervous System Diseases; Mental Disorders
C0028754	BXGD002082	Obesity	Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0034951	BXGD002498	Refractive Errors	Eye Diseases
C0036341	BXGD002600	Schizophrenia	Mental Disorders
C0036572	BXGD002625	Seizures	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0085281	BXGD003152	Addictive Behavior	Behavior and Behavior Mechanisms
C0149958	BXGD003395	Complex partial seizures	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0202177	BXGD004079	Phospholipid measurement
C0234533	BXGD004687	Generalized seizures	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0234535	BXGD004688	Clonic Seizures	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0238288	BXGD004905	Muscular Dystrophy, Facioscapulohumeral	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0242379	BXGD005157	Malignant neoplasm of lung	Neoplasms; Respiratory Tract Diseases
C0263746	BXGD005346	Osteoarthritis of the hand	Musculoskeletal Diseases
C0270824	BXGD006113	Visual seizure	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0270844	BXGD006115	Tonic Seizures	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0270846	BXGD006116	Epileptic drop attack	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0270850	BXGD006117	Idiopathic generalized epilepsy	Nervous System Diseases
C0271183	BXGD006169	Severe myopia	Eye Diseases
C0338656	BXGD007211	Impaired cognition	Mental Disorders
C0376300	BXGD007987	Dengue Shock Syndrome	Infections
C0376532	BXGD008000	Epilepsy, Rolandic	Nervous System Diseases
C0391957	BXGD008019	idiopathic epilepsy
C0410702	BXGD008447	Adolescent idiopathic scoliosis	Musculoskeletal Diseases
C0422850	BXGD008457	Seizures, Somatosensory	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0422852	BXGD008458	Seizures, Auditory	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0422853	BXGD008459	Olfactory seizure	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0422854	BXGD008460	Gustatory seizure	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0422855	BXGD008461	Vertiginous seizure	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0424295	BXGD008524	Hyperactive behavior	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0424574	BXGD008534	Duration of sleep
C0424605	BXGD008535	Developmental delay (disorder)	Mental Disorders
C0494475	BXGD009030	Tonic - clonic seizures	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0523465	BXGD009209	Serum albumin measurement
C0524528	BXGD009229	Pervasive Development Disorder	Mental Disorders
C0525045	BXGD009255	Mood Disorders	Mental Disorders
C0557874	BXGD009444	Global developmental delay
C0596887	BXGD009648	mathematical ability
C0751056	BXGD010306	Non-epileptic convulsion	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0751110	BXGD010318	Single Seizure	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0751123	BXGD010326	Atonic Absence Seizures	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0751494	BXGD010472	Convulsive Seizures	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0751495	BXGD010473	Seizures, Focal	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0751496	BXGD010474	Seizures, Sensory	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0871470	BXGD011316	Systolic Pressure
C0878544	BXGD011368	Cardiomyopathies	Cardiovascular Diseases
C0949570	BXGD011579	Wheat Hypersensitivity	Immune System Diseases
C1096063	BXGD011600	Drug Resistant Epilepsy	Nervous System Diseases
C1263846	BXGD011897	Attention deficit hyperactivity disorder	Mental Disorders
C1269683	BXGD012001	Major Depressive Disorder	Mental Disorders
C1305855	BXGD012348	Body mass index
C1314691	BXGD012388	Age at menarche	Behavior and Behavior Mechanisms
C1504404	BXGD013141	Hippocampal sclerosis
C1510586	BXGD013176	Autism Spectrum Disorders	Mental Disorders
C1519383	BXGD013237	Smoking Behaviors	Behavior and Behavior Mechanisms
C1535926	BXGD013322	Neurodevelopmental Disorders	Mental Disorders
C1621958	BXGD013468	Glioblastoma Multiforme	Neoplasms
C1636149	BXGD013482	Macular dystrophy, corneal type 1	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C1704436	BXGD013564	Peripheral Arterial Diseases	Cardiovascular Diseases
C1837461	BXGD014234	SCOLIOSIS, ISOLATED, SUSCEPTIBILITY TO, 3
C1863416	BXGD016179	Autosomal dominant compelling helio ophthalmic outburst syndrome	Pathological Conditions, Signs and Symptoms
C2363129	BXGD017095	Benign Rolandic Epilepsy	Nervous System Diseases
C2607914	BXGD017148	Allergic rhinitis (disorder)	Respiratory Tract Diseases; Immune System Diseases; Otorhinolaryngologic Diseases
C3250443	BXGD018584	MYOTONIC DYSTROPHY 1	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C3495874	BXGD019008	Nonepileptic Seizures	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C3714756	BXGD019429	Intellectual Disability	Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C4025843	BXGD021823	Abnormality of refraction
C4048158	BXGD021890	Convulsions	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C4316903	BXGD022711	Absence Seizures	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C4317109	BXGD022725	Epileptic Seizures	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C4317123	BXGD022727	Myoclonic Seizures	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C4505436	BXGD022962	Generalized Absence Seizures	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C4521042	BXGD023055	Complete Trisomy 21 Syndrome	Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C4554344	BXGD023564	IgE-mediated food allergy	Immune System Diseases

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0030612	tetraethylene glycol		194.12

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}