Showing entry for Malaria, Falciparum


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD001785
Disease NameMalaria, Falciparum
Disease CUI IdC0024535
MeSH Codes C01  
Disease Class NameInfections
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:0050117  
Disease Ontology Class Namedisease by infectious agent
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O00764 BXGT003948 Pyridoxal kinase 8566 reviewed Kinase
O15123 BXGT004130 Angiopoietin-2 285 reviewed Signaling
O43524 BXGT004599 Forkhead box protein O3 2309 reviewed
O60656 BXGT004889 UDP-glucuronosyltransferase 1-9 54600 reviewed
O75015 BXGT005095 Low affinity immunoglobulin gamma Fc region receptor III-B 2215 reviewed Cell adhesion
O95749 BXGT005394 Geranylgeranyl pyrophosphate synthase 9453 reviewed
P00374 BXGT005520 Dihydrofolate reductase 1719 reviewed Enzyme
P00390 BXGT005526 Glutathione reductase, mitochondrial 2936 reviewed Enzyme
P01011 BXGT005715 Alpha-1-antichymotrypsin 12 reviewed Enzyme modulator
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P01889 BXGT005809 HLA class I histocompatibility antigen, B-7 alpha chain 3106 reviewed
P01911 BXGT005816 HLA class II histocompatibility antigen, DRB1-15 beta chain 3123 reviewed Immune response
P02100 BXGT005845 Hemoglobin subunit epsilon 3046 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P04839 BXGT006273 Cytochrome b-245 heavy chain 1536 reviewed Ion channel
P05362 BXGT006350 Intercellular adhesion molecule 1 3383 reviewed
P07203 BXGT006566 Glutathione peroxidase 1 2876 reviewed Enzyme
P07204 BXGT006567 Thrombomodulin 7056 reviewed
P07550 BXGT006636 Beta-2 adrenergic receptor 154 reviewed G-protein coupled receptor
P08183 BXGT006741 ATP-dependent translocase ABCB1 5243 reviewed Transporter
P08637 BXGT006802 Low affinity immunoglobulin gamma Fc region receptor III-A 2214 reviewed Cell adhesion
P08700 BXGT006816 Interleukin-3 3562 reviewed
P09211 BXGT006869 Glutathione S-transferase P 2950 reviewed
P09488 BXGT006899 Glutathione S-transferase Mu 1 2944 reviewed
P09601 BXGT006909 Heme oxygenase 1 3162 reviewed
P0DMV8 BXGT007509 Heat shock 70 kDa protein 1A 3304 reviewed
P0DMV9 BXGT007510 Heat shock 70 kDa protein 1B 3304 reviewed
P10144 BXGT007541 Granzyme B 3002 reviewed Enzyme
P10632 BXGT007592 Cytochrome P450 2C8 1558 reviewed
P10909 BXGT007630 Clusterin 1191 reviewed
P11226 BXGT007675 Mannose-binding protein C 4153 reviewed Receptor
P11413 BXGT007701 Glucose-6-phosphate 1-dehydrogenase 2539 reviewed Enzyme
P12318 BXGT007799 Low affinity immunoglobulin gamma Fc region receptor II-a 2212 reviewed Cell adhesion
P13501 BXGT007917 C-C motif chemokine 5 6352 reviewed Signaling
P13726 BXGT007950 Tissue factor 2152 reviewed Receptor
P14174 BXGT007991 Macrophage migration inhibitory factor 4282 reviewed
P14324 BXGT008005 Farnesyl pyrophosphate synthase 2224 reviewed Enzyme
P14598 BXGT008024 Neutrophil cytosol factor 1 653361 reviewed
P14616 BXGT008026 Insulin receptor-related protein 3645 reviewed Kinase
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P16442 BXGT008227 Histo-blood group ABO system transferase 28 reviewed Enzyme
P16581 BXGT008245 E-selectin 6401 reviewed
P16671 BXGT008255 Platelet glycoprotein 4 948 reviewed Receptor
P16871 BXGT008269 Interleukin-7 receptor subunit alpha 3575 reviewed Receptor
P22749 BXGT008803 Granulysin 10578 reviewed
P28161 BXGT009234 Glutathione S-transferase Mu 2 2946 reviewed
P29274 BXGT009327 Adenosine receptor A2a 135 reviewed G-protein coupled receptor
P29460 BXGT009348 Interleukin-12 subunit beta 3593 reviewed Signaling
P29475 BXGT009353 Nitric oxide synthase, brain 4842 reviewed
P29965 BXGT009388 CD40 ligand 959 reviewed Signaling
P34947 BXGT009774 G protein-coupled receptor kinase 5 2869 reviewed Kinase
P35228 BXGT009800 Nitric oxide synthase, inducible 4843 reviewed
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35613 BXGT009856 Basigin 682 reviewed
P36222 BXGT009914 Chitinase-3-like protein 1 1116 reviewed
P36871 BXGT009936 Phosphoglucomutase-1 5236 reviewed
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P51681 BXGT010878 C-C chemokine receptor type 5 1234 reviewed G-protein coupled receptor
P58753 BXGT011247 Toll/interleukin-1 receptor domain-containing adapter protein 114609 reviewed
P60568 BXGT011315 Interleukin-2 3558 reviewed
P62258 BXGT011415 14-3-3 protein epsilon 7531 reviewed Chaperone
P63261 BXGT011512 Actin, cytoplasmic 2 71 reviewed Cellular structure
P68871 BXGT011615 Hemoglobin subunit beta 3043 reviewed
P81172 BXGT011935 Hepcidin 57817 reviewed
Q08722 BXGT013002 Leukocyte surface antigen CD47 961 reviewed
Q13231 BXGT013329 Chitotriosidase-1 1118 reviewed
Q13427 BXGT013354 Peptidyl-prolyl cis-trans isomerase G 9360 reviewed
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q16637 BXGT013646 Survival motor neuron protein 6607 reviewed Epigenetic regulator
Q5VWK5 BXGT015891 Interleukin-23 receptor 149233 reviewed Signaling
Q76LX8 BXGT016870 A disintegrin and metalloproteinase with thrombospondin motifs 13 11093 reviewed Enzyme
Q7L5Y1 BXGT016996 Mitochondrial enolase superfamily member 1 55556 reviewed Enzyme
Q8TDQ0 BXGT018810 Hepatitis A virus cellular receptor 2 84868 reviewed
Q92887 BXGT019389 Canalicular multispecific organic anion transporter 1 1244 reviewed Transporter
Q96H15 BXGT019669 T-cell immunoglobulin and mucin domain-containing protein 4 91937 reviewed
Q96RQ3 BXGT019732 Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial 56922 reviewed Enzyme
Q9BZS1 BXGT020203 Forkhead box protein P3 50943 reviewed
Q9NPH2 BXGT021158 Inositol-3-phosphate synthase 1 51477 reviewed
Q9NR96 BXGT021181 Toll-like receptor 9 54106 reviewed
Q9UH17 BXGT021691 DNA dC->dU-editing enzyme APOBEC-3B 9582 reviewed Enzyme
Q9UNN8 BXGT021791 Endothelial protein C receptor 10544 reviewed Enzyme modulator
P04439 BXGT022649 HLA class I histocompatibility antigen, A-3 alpha chain 3105 reviewed
Q96C86 BXGT022803 m7GpppX diphosphatase 28960 reviewed Enzyme
P00738 BXGT022874 Haptoglobin 3240 reviewed Enzyme
P16284 BXGT022972 Platelet endothelial cell adhesion molecule 5175 reviewed Cell adhesion
P31994 BXGT023298 Low affinity immunoglobulin gamma Fc region receptor II-b 2213 reviewed Cell adhesion
P15260 BXGT023924 Interferon gamma receptor 1 3459 reviewed Receptor
Q9BYE2 BXGT024631 Transmembrane protease serine 13 84000 reviewed Enzyme
P51608 BXGT025073 Methyl-CpG-binding protein 2 4204 reviewed Epigenetic regulator
P00403 BXGT026137 Cytochrome c oxidase subunit 2 4513 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease