adisease

Showing entry for Polycythemia

General Disease Information
BXGD Id	BXGD002356
Disease Name	Polycythemia
Disease CUI Id	C0032461
MeSH Codes	C15
Disease Class Name	Hemic and Lymphatic Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0001871
Human Phenotype Ontology Term	Abnormality of blood and blood-forming tissues
Disease Ontology Id	DOID:630 DOID:7
Disease Ontology Class Name	genetic disease; disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00459	BXGT003924	Phosphatidylinositol 3-kinase regulatory subunit beta	5296	reviewed	Enzyme modulator
O60674	BXGT004892	Tyrosine-protein kinase JAK2	3717	reviewed	Kinase
P00387	BXGT005525	NADH-cytochrome b5 reductase 3	1727	reviewed
P00519	BXGT005570	Tyrosine-protein kinase ABL1	25	reviewed	Kinase
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P02724	BXGT005934	Glycophorin-A	2993	reviewed
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P05121	BXGT006320	Plasminogen activator inhibitor 1	5054	reviewed	Enzyme modulator
P06870	BXGT006518	Kallikrein-1	3816	reviewed	Enzyme
P08631	BXGT006801	Tyrosine-protein kinase HCK	3055	reviewed	Kinase
P11274	BXGT007681	Breakpoint cluster region protein	613	reviewed	Enzyme modulator
P11413	BXGT007701	Glucose-6-phosphate 1-dehydrogenase	2539	reviewed	Enzyme
P14174	BXGT007991	Macrophage migration inhibitory factor	4282	reviewed
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P19838	BXGT008526	Nuclear factor NF-kappa-B p105 subunit	4790	reviewed	Transcription factor
P21399	BXGT008646	Cytoplasmic aconitate hydratase	48	reviewed	Enzyme
P24385	BXGT008965	G1/S-specific cyclin-D1	595	reviewed	Enzyme modulator
P25713	BXGT009062	Metallothionein-3	4504	reviewed
P25942	BXGT009079	Tumor necrosis factor receptor superfamily member 5	958	reviewed
P27352	BXGT009174	Cobalamin binding intrinsic factor	2694	reviewed
P27986	BXGT009216	Phosphatidylinositol 3-kinase regulatory subunit alpha	5295	reviewed	Kinase
P30613	BXGT009447	Pyruvate kinase PKLR	5313	reviewed	Kinase
P35555	BXGT009845	Fibrillin-1	2200	reviewed	Calcium-binding protein
P37023	BXGT009953	Serine/threonine-protein kinase receptor R3	94	reviewed	Kinase
P40337	BXGT010174	von Hippel-Lindau disease tumor suppressor	7428	reviewed	Enzyme
P45983	BXGT010494	Mitogen-activated protein kinase 8	5599	reviewed	Kinase
P45984	BXGT010495	Mitogen-activated protein kinase 9	5601	reviewed	Kinase
P51692	BXGT010885	Signal transducer and activator of transcription 5B	6777	reviewed	Nucleic acid binding
P58004	BXGT011222	Sestrin-2	83667	reviewed	Enzyme
P68871	BXGT011615	Hemoglobin subunit beta	3043	reviewed
P69892	BXGT011647	Hemoglobin subunit gamma-2	3048	reviewed
Q01196	BXGT012575	Runt-related transcription factor 1	861	reviewed	Transcription factor
Q07817	BXGT012941	Bcl-2-like protein 1	598	reviewed	Signaling
Q15369	BXGT013560	Elongin-C	6921	reviewed	Enzyme modulator
Q15370	BXGT013561	Elongin-B	6923	reviewed	Transcription factor
Q16665	BXGT013653	Hypoxia-inducible factor 1-alpha	3091	reviewed	Transcription factor
Q96KS0	BXGT019688	Egl nine homolog 2	112398	reviewed
Q99814	BXGT019965	Endothelial PAS domain-containing protein 1	2034	reviewed	Transcription factor
Q9BYW2	BXGT020192	Histone-lysine N-methyltransferase SETD2	29072	reviewed	Epigenetic regulator
Q9GZT9	BXGT020425	Egl nine homolog 1	54583	reviewed
Q9H6Z9	BXGT020488	Egl nine homolog 3	112399	reviewed
Q9Y5K2	BXGT022293	Kallikrein-4	9622	reviewed	Enzyme
P19235	BXGT022895	Erythropoietin receptor	2057	reviewed	Receptor
P07954	BXGT023939	Fumarate hydratase, mitochondrial	2271	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}