Showing entry for Cardiomyopathies, Primary


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD002400
Disease NameCardiomyopathies, Primary
Disease CUI IdC0033141
MeSH Codes C14  
Disease Class NameCardiovascular Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7  
Disease Ontology Class Namedisease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00408 BXGT003916 cGMP-dependent 3',5'-cyclic phosphodiesterase 5138 reviewed
O14672 BXGT004081 Disintegrin and metalloproteinase domain-containing protein 10 102 reviewed
O60603 BXGT004887 Toll-like receptor 2 7097 reviewed
O75306 BXGT005108 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial 4720 reviewed Enzyme
O75365 BXGT005115 Protein tyrosine phosphatase type IVA 3 11156 reviewed
O75390 BXGT005123 Citrate synthase, mitochondrial 1431 reviewed Enzyme
O95622 BXGT005386 Adenylate cyclase type 5 111 reviewed
P00338 BXGT005504 L-lactate dehydrogenase A chain 3939 reviewed Enzyme
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P01112 BXGT005732 GTPase HRas 3265 reviewed Enzyme modulator
P01189 BXGT005742 Pro-opiomelanocortin 5443 reviewed
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P01911 BXGT005816 HLA class II histocompatibility antigen, DRB1-15 beta chain 3123 reviewed Immune response
P02766 BXGT005953 Transthyretin 7276 reviewed Transporter
P04040 BXGT006132 Catalase 847 reviewed Enzyme
P04179 BXGT006163 Superoxide dismutase [Mn], mitochondrial 6648 reviewed Enzyme
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P05067 BXGT006306 Amyloid-beta precursor protein 351 reviewed Enzyme modulator
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05556 BXGT006368 Integrin beta-1 3688 reviewed Receptor
P06576 BXGT006454 ATP synthase subunit beta, mitochondrial 506 reviewed Transporter
P06858 BXGT006515 Lipoprotein lipase 4023 reviewed Enzyme
P07550 BXGT006636 Beta-2 adrenergic receptor 154 reviewed G-protein coupled receptor
P08069 BXGT006723 Insulin-like growth factor 1 receptor 3480 reviewed Kinase
P09874 BXGT006934 Poly [ADP-ribose] polymerase 1 142 reviewed
P10599 BXGT007583 Thioredoxin 7295 reviewed
P10636 BXGT007596 Microtubule-associated protein tau 4137 reviewed
P10809 BXGT007617 60 kDa heat shock protein, mitochondrial 3329 reviewed
P11712 BXGT007738 Cytochrome P450 2C9 1559 reviewed
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P14174 BXGT007991 Macrophage migration inhibitory factor 4282 reviewed
P14210 BXGT007994 Hepatocyte growth factor 3082 reviewed Enzyme
P16152 BXGT008201 Carbonyl reductase [NADPH] 1 873 reviewed
P17174 BXGT008289 Aspartate aminotransferase, cytoplasmic 2805 reviewed
P18847 BXGT008431 Cyclic AMP-dependent transcription factor ATF-3 467 reviewed Transcription factor
P19404 BXGT008477 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial 4729 reviewed
P19429 BXGT008479 Troponin I, cardiac muscle 7137 reviewed Cellular structure
P25098 BXGT009015 Beta-adrenergic receptor kinase 1 156 reviewed Kinase
P27352 BXGT009174 Cobalamin binding intrinsic factor 2694 reviewed
P27361 BXGT009176 Mitogen-activated protein kinase 3 5595 reviewed Kinase
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P29274 BXGT009327 Adenosine receptor A2a 135 reviewed G-protein coupled receptor
P29474 BXGT009352 Nitric oxide synthase, endothelial 4846 reviewed
P29475 BXGT009353 Nitric oxide synthase, brain 4842 reviewed
P30411 BXGT009424 B2 bradykinin receptor 624 reviewed G-protein coupled receptor
P30518 BXGT009428 Vasopressin V2 receptor 554 reviewed G-protein coupled receptor
P30556 BXGT009441 Type-1 angiotensin II receptor 185 reviewed G-protein coupled receptor
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P33121 BXGT009692 Long-chain-fatty-acid--CoA ligase 1 2180 reviewed Enzyme
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P40225 BXGT010168 Thrombopoietin 7066 reviewed
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P41180 BXGT010230 Extracellular calcium-sensing receptor 846 reviewed G-protein coupled receptor
P45379 BXGT010459 Troponin T, cardiac muscle 7139 reviewed Cellular structure
P47989 BXGT010602 Xanthine dehydrogenase/oxidase 7498 reviewed Enzyme
P48023 BXGT010604 Tumor necrosis factor ligand superfamily member 6 356 reviewed Signaling
P49768 BXGT010740 Presenilin-1 5663 reviewed Enzyme
P54646 BXGT011062 5'-AMP-activated protein kinase catalytic subunit alpha-2 5563 reviewed Kinase
P61604 BXGT011380 10 kDa heat shock protein, mitochondrial 3336 reviewed Chaperone
P68106 BXGT011576 Peptidyl-prolyl cis-trans isomerase FKBP1B 2281 reviewed Enzyme
P78380 BXGT011841 Oxidized low-density lipoprotein receptor 1 4973 reviewed
Q02156 BXGT012639 Protein kinase C epsilon type 5581 reviewed Kinase
Q03181 BXGT012701 Peroxisome proliferator-activated receptor delta 5467 reviewed Nuclear receptor
Q04917 BXGT012791 14-3-3 protein eta 7533 reviewed Chaperone
Q06609 BXGT012884 DNA repair protein RAD51 homolog 1 5888 reviewed
Q07954 BXGT012950 Prolow-density lipoprotein receptor-related protein 1 4035 reviewed
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q14126 BXGT013446 Desmoglein-2 1829 reviewed Cell adhesion
Q15119 BXGT013541 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial 5164 reviewed Kinase
Q15759 BXGT013595 Mitogen-activated protein kinase 11 5600 reviewed Kinase
Q16539 BXGT013634 Mitogen-activated protein kinase 14 1432 reviewed Kinase
Q969Q1 BXGT019610 E3 ubiquitin-protein ligase TRIM63 84676 reviewed
Q99683 BXGT019947 Mitogen-activated protein kinase kinase kinase 5 4217 reviewed Kinase
P00395 BXGT023596 Cytochrome c oxidase subunit 1 4512 reviewed Enzyme
O95399 BXGT024237 Urotensin-2 10911 reviewed
Q9UKP6 BXGT024239 Urotensin-2 receptor 2837 reviewed G-protein coupled receptor
V9HWB9 BXGT026149 L-lactate dehydrogenase 3939 unreviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease