Showing entry for Apolipoprotein D


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT006311
Protein NameApolipoprotein D
Uniport IdP05090
GeneAPOD
Gene Id347
DomainLipocalin_2
Pfam PF08212  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007568 aging
Biological Process GO:0001525 angiogenesis
Biological Process GO:0007420 brain development
Biological Process GO:0006006 glucose metabolic process
Biological Process GO:0006629 lipid metabolic process
Biological Process GO:1900016 negative regulation of cytokine production involved in inflammatory response
Biological Process GO:0051895 negative regulation of focal adhesion assembly
Biological Process GO:0060588 negative regulation of lipoprotein lipid oxidation
Biological Process GO:0071638 negative regulation of monocyte chemotactic protein-1 production
Biological Process GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway
Biological Process GO:0042308 negative regulation of protein import into nucleus
Biological Process GO:2000098 negative regulation of smooth muscle cell-matrix adhesion
Biological Process GO:0048662 negative regulation of smooth muscle cell proliferation
Biological Process GO:2000405 negative regulation of T cell migration
Biological Process GO:0014012 peripheral nervous system axon regeneration
Biological Process GO:0048678 response to axon injury
Biological Process GO:0042493 response to drug
Biological Process GO:0000302 response to reactive oxygen species
Biological Process GO:0042246 tissue regeneration
molecular function GO:0015485 cholesterol binding
molecular function GO:0005319 lipid transporter activity
cellular component GO:0005737 cytoplasm
cellular component GO:0022626 cytosolic ribosome
cellular component GO:0030425 dendrite
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0070062 extracellular exosome
cellular component GO:0005576 extracellular region
cellular component GO:0005615 extracellular space
cellular component GO:0043025 neuronal cell body
cellular component GO:0048471 perinuclear region of cytoplasm
Reactome
Pathway Id Pathway Name
R-HSA-162582 Signal Transduction
R-HSA-382551 Transport of small molecules
R-HSA-425397 Transport of vitamins, nucleosides, and related molecules
R-HSA-425407 SLC-mediated transmembrane transport
R-HSA-804914 Transport of fatty acids
R-HSA-9006931 Signaling by Nuclear Receptors
R-HSA-9024446 NR1H2 and NR1H3-mediated signaling
R-HSA-9029569 NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001430 BXGD000054 Adenoma Neoplasms
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0004114 BXGD000255 Astrocytoma Neoplasms
C0004936 BXGD000295 Mental disorders Mental Disorders
C0005586 BXGD000315 Bipolar Disorder Mental Disorders
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0010054 BXGD000647 Coronary Arteriosclerosis Cardiovascular Diseases
C0010068 BXGD000648 Coronary heart disease Cardiovascular Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0014038 BXGD000878 Encephalitis Nervous System Diseases
C0015695 BXGD001013 Fatty Liver Digestive System Diseases
C0016045 BXGD001037 fibroma Neoplasms
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0018055 BXGD001169 Gonadal Dysgenesis, Mixed Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0020443 BXGD001385 Hypercholesterolemia Nutritional and Metabolic Diseases
C0020459 BXGD001394 Hyperinsulinism Nutritional and Metabolic Diseases
C0020550 BXGD001429 Hyperthyroidism Endocrine System Diseases
C0021368 BXGD001502 Inflammation Pathological Conditions, Signs and Symptoms
C0023186 BXGD001613 Learning Disorders Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0027765 BXGD002033 nervous system disorder Nervous System Diseases
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0035335 BXGD002540 Retinoblastoma Neoplasms; Eye Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0038220 BXGD002740 Status Epilepticus Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0039585 BXGD002821 Androgen-Insensitivity Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0085136 BXGD003131 Central Nervous System Neoplasms Neoplasms; Nervous System Diseases
C0086439 BXGD003284 Hypokinesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0162835 BXGD003989 Hypopigmentation disorder Skin and Connective Tissue Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0206064 BXGD004150 Microvascular Angina Cardiovascular Diseases
C0206647 BXGD004212 Dermatofibrosarcoma Neoplasms
C0220756 BXGD004338 Niemann-Pick Disease, Type C Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases; Hemic and Lymphatic Diseases
C0233514 BXGD004584 Abnormal behavior Behavior and Behavior Mechanisms
C0233565 BXGD004590 Bradykinesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0236642 BXGD004815 Pick Disease of the Brain Nervous System Diseases; Mental Disorders
C0242684 BXGD005188 Hypodynamia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0243000 BXGD005206 Impotence, Vasculogenic Male Urogenital Diseases
C0259783 BXGD005221 mixed gliomas Neoplasms
C0263472 BXGD005310 Bromhidrosis Skin and Connective Tissue Diseases
C0270715 BXGD006089 Degenerative Diseases, Central Nervous System Nervous System Diseases
C0280781 BXGD006758 Adult Pilocytic Astrocytoma Neoplasms
C0334579 BXGD007120 Anaplastic astrocytoma Neoplasms
C0334583 BXGD007124 Pilocytic Astrocytoma Neoplasms
C0338451 BXGD007176 Frontotemporal dementia Nutritional and Metabolic Diseases; Nervous System Diseases; Mental Disorders
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0476089 BXGD008977 Endometrial Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0494463 BXGD009029 Alzheimer Disease, Late Onset Nervous System Diseases; Mental Disorders
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0555198 BXGD009432 Malignant Glioma Neoplasms
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0751262 BXGD010368 Adult Learning Disorders Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
C0751263 BXGD010369 Learning Disturbance Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
C0751265 BXGD010370 Learning Disabilities Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
C0751701 BXGD010558 Hypokinesia, Antiorthostatic Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0751733 BXGD010569 Degenerative Diseases, Spinal Cord Nervous System Diseases
C0948008 BXGD011499 Ischemic stroke Nervous System Diseases; Cardiovascular Diseases
C1168327 BXGD011787 High-Grade Prostatic Intraepithelial Neoplasia Neoplasms; Male Urogenital Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1330966 BXGD012478 Developmental Academic Disorder Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C1332995 BXGD012575 Childhood Pilocytic Astrocytoma Neoplasms
C1510586 BXGD013176 Autism Spectrum Disorders Mental Disorders
C1843013 BXGD014549 Alzheimer disease, familial, type 3 Nervous System Diseases; Mental Disorders
C1862382 BXGD016125 SVEINSSON CHORIORETINAL ATROPHY Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C1868938 BXGD016542 End stage cardiac failure
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2711227 BXGD017478 Steatohepatitis Digestive System Diseases
C2930619 BXGD017890 Sex Differentiation Disorders Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C3160718 BXGD018468 PARKINSON DISEASE, LATE-ONSET
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0001325 Progesterone 314.46
BXGC0002616 Copper 63.55
BXGC0047568 Retinol 286.23
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein