adisease

Showing entry for Liver Dysfunction

General Disease Information
BXGD Id	BXGD003295
Disease Name	Liver Dysfunction
Disease CUI Id	C0086565
MeSH Codes	C06
Disease Class Name	Digestive System Diseases
Semantic Type	Finding
Human Phenotype Ontology Id	HP:0025031
Human Phenotype Ontology Term	Abnormality of the digestive system
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O14786	BXGT004099	Neuropilin-1	8829	reviewed
O15118	BXGT004127	NPC intracellular cholesterol transporter 1	4864	reviewed	Transporter
O43914	BXGT004635	TYRO protein tyrosine kinase-binding protein	7305	reviewed
O60760	BXGT004899	Hematopoietic prostaglandin D synthase	27306	reviewed
O75880	BXGT005158	Protein SCO1 homolog, mitochondrial	6341	reviewed	Enzyme
O94760	BXGT005328	N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	23576	reviewed	Enzyme
P00441	BXGT005540	Superoxide dismutase [Cu-Zn]	6647	reviewed	Enzyme
P01009	BXGT005714	Alpha-1-antitrypsin	5265	reviewed	Enzyme modulator
P01308	BXGT005749	Insulin	3630	reviewed
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P02461	BXGT005880	Collagen alpha-1(III) chain	1281	reviewed
P05121	BXGT006320	Plasminogen activator inhibitor 1	5054	reviewed	Enzyme modulator
P05177	BXGT006336	Cytochrome P450 1A2	1544	reviewed	Enzyme
P05186	BXGT006338	Alkaline phosphatase, tissue-nonspecific isozyme	249	reviewed	Enzyme
P09601	BXGT006909	Heme oxygenase 1	3162	reviewed
P10599	BXGT007583	Thioredoxin	7295	reviewed
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P13716	BXGT007948	Delta-aminolevulinic acid dehydratase	210	reviewed	Enzyme
P13929	BXGT007971	Beta-enolase	2027	reviewed	Enzyme
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P14923	BXGT008069	Junction plakoglobin	3728	reviewed
P15559	BXGT008139	NAD(P)H dehydrogenase [quinone] 1	1728	reviewed
P18564	BXGT008414	Integrin beta-6	3694	reviewed	Receptor
P19440	BXGT008481	Glutathione hydrolase 1 proenzyme	2678	reviewed	Enzyme
P19838	BXGT008526	Nuclear factor NF-kappa-B p105 subunit	4790	reviewed	Transcription factor
P20292	BXGT008561	Arachidonate 5-lipoxygenase-activating protein	241	reviewed	Enzyme
P21439	BXGT008649	Phosphatidylcholine translocator ABCB4	5244	reviewed	Transporter
P24298	BXGT008960	Alanine aminotransferase 1	2875	reviewed	Enzyme
P28476	BXGT009262	Gamma-aminobutyric acid receptor subunit rho-2	2570	reviewed	Ion channel
P34947	BXGT009774	G protein-coupled receptor kinase 5	2869	reviewed	Kinase
P35228	BXGT009800	Nitric oxide synthase, inducible	4843	reviewed
P35869	BXGT009877	Aryl hydrocarbon receptor	196	reviewed	Transcription factor
P41597	BXGT010268	C-C chemokine receptor type 2	729230	reviewed
P42898	BXGT010344	Methylenetetrahydrofolate reductase	4524	reviewed
P49888	BXGT010756	Estrogen sulfotransferase	6783	reviewed
P52790	BXGT010955	Hexokinase-3	3101	reviewed	Kinase
P62736	BXGT011452	Actin, aortic smooth muscle	59	reviewed	Cellular structure
P63000	BXGT011481	Ras-related C3 botulinum toxin substrate 1	5879	reviewed	Enzyme modulator
Q07817	BXGT012941	Bcl-2-like protein 1	598	reviewed	Signaling
Q15722	BXGT013590	Leukotriene B4 receptor 1	1241	reviewed	G-protein coupled receptor
Q93091	BXGT019459	Ribonuclease K6	6039	reviewed
Q96RI1	BXGT019727	Bile acid receptor	9971	reviewed	Nuclear receptor
Q99523	BXGT019929	Sortilin	6272	reviewed	Transporter
Q9NP99	BXGT021148	Triggering receptor expressed on myeloid cells 1	54210	reviewed
Q9NR71	BXGT021180	Neutral ceramidase	56624	reviewed
P35670	BXGT023695	Copper-transporting ATPase 2	540	reviewed	Transporter
P20809	BXGT025043	Interleukin-11	3589	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}