Showing entry for Primary immune deficiency disorder


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD008215
Disease NamePrimary immune deficiency disorder
Disease CUI IdC0398686
MeSH Codes C20  
Disease Class NameImmune System Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O14920 BXGT004110 Inhibitor of nuclear factor kappa-B kinase subunit beta 3551 reviewed Kinase
O15553 BXGT004181 Pyrin 4210 reviewed
O75369 BXGT005119 Filamin-B 2317 reviewed
O76054 BXGT005172 SEC14-like protein 2 23541 reviewed
O95819 BXGT005398 Mitogen-activated protein kinase kinase kinase kinase 4 9448 reviewed Kinase
P00813 BXGT005667 Adenosine deaminase 100 reviewed Enzyme
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P02786 BXGT005961 Transferrin receptor protein 1 7037 reviewed Enzyme
P10747 BXGT007609 T-cell-specific surface glycoprotein CD28 940 reviewed
P15531 BXGT008136 Nucleoside diphosphate kinase A 4830 reviewed Kinase
P16871 BXGT008269 Interleukin-7 receptor subunit alpha 3575 reviewed Receptor
P23458 BXGT008868 Tyrosine-protein kinase JAK1 3716 reviewed Kinase
P27986 BXGT009216 Phosphatidylinositol 3-kinase regulatory subunit alpha 5295 reviewed Kinase
P29597 BXGT009367 Non-receptor tyrosine-protein kinase TYK2 7297 reviewed Kinase
P29965 BXGT009388 CD40 ligand 959 reviewed Signaling
P31785 BXGT009577 Cytokine receptor common subunit gamma 3561 reviewed Signaling
P35610 BXGT009855 Sterol O-acyltransferase 1 6646 reviewed Enzyme
P35916 BXGT009881 Vascular endothelial growth factor receptor 3 2324 reviewed Kinase
P38484 BXGT010042 Interferon gamma receptor 2 3460 reviewed Receptor
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P52333 BXGT010928 Tyrosine-protein kinase JAK3 3718 reviewed Kinase
P61073 BXGT011352 C-X-C chemokine receptor type 4 7852 reviewed G-protein coupled receptor
P78527 BXGT011846 DNA-dependent protein kinase catalytic subunit 5591 reviewed Kinase
P98170 BXGT012231 E3 ubiquitin-protein ligase XIAP 331 reviewed Enzyme modulator
Q00653 BXGT012541 Nuclear factor NF-kappa-B p100 subunit 4791 reviewed Transcription factor
Q06187 BXGT012860 Tyrosine-protein kinase BTK 695 reviewed Kinase
Q13315 BXGT013339 Serine-protein kinase ATM 472 reviewed Kinase
Q13478 BXGT013362 Interleukin-18 receptor 1 8809 reviewed Receptor
Q13546 BXGT013372 Receptor-interacting serine/threonine-protein kinase 1 8737 reviewed Kinase
Q15833 BXGT013605 Syntaxin-binding protein 2 6813 reviewed Transporter
Q16698 BXGT013659 2,4-dienoyl-CoA reductase, mitochondrial 1666 reviewed Enzyme
Q99558 BXGT019934 Mitogen-activated protein kinase kinase kinase 14 9020 reviewed Kinase
Q9BXL7 BXGT020171 Caspase recruitment domain-containing protein 11 84433 reviewed
Q9BYW2 BXGT020192 Histone-lysine N-methyltransferase SETD2 29072 reviewed Epigenetic regulator
Q9BZS1 BXGT020203 Forkhead box protein P3 50943 reviewed
Q9GZX6 BXGT020428 Interleukin-22 50616 reviewed
Q9HBE5 BXGT020518 Interleukin-21 receptor 50615 reviewed Receptor
Q9NWZ3 BXGT021239 Interleukin-1 receptor-associated kinase 4 51135 reviewed Kinase
Q9UKU7 BXGT021749 Isobutyryl-CoA dehydrogenase, mitochondrial 27034 reviewed Enzyme
Q9UL54 BXGT021755 Serine/threonine-protein kinase TAO2 9344 reviewed Kinase
Q9Y6K9 BXGT022333 NF-kappa-B essential modulator 8517 reviewed Kinase
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
P15260 BXGT023924 Interferon gamma receptor 1 3459 reviewed Receptor
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease