Showing entry for Serine/threonine-protein kinase TAO2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT021755
Protein NameSerine/threonine-protein kinase TAO2
Uniport IdQ9UL54
GeneTAOK2
Gene Id9344
DomainPkinase
Pfam PF00069  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04010 MAPK signaling pathway
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0030036 actin cytoskeleton organization
Biological Process GO:0007257 activation of JUN kinase activity
Biological Process GO:0000187 activation of MAPK activity
Biological Process GO:0000186 activation of MAPKK activity
Biological Process GO:0032147 activation of protein kinase activity
Biological Process GO:0006915 apoptotic process
Biological Process GO:0007409 axonogenesis
Biological Process GO:0150020 basal dendrite arborization
Biological Process GO:0150019 basal dendrite morphogenesis
Biological Process GO:0016477 cell migration
Biological Process GO:0006974 cellular response to DNA damage stimulus
Biological Process GO:0048041 focal adhesion assembly
Biological Process GO:0007095 mitotic G2 DNA damage checkpoint
Biological Process GO:0048812 neuron projection morphogenesis
Biological Process GO:0046330 positive regulation of JNK cascade
Biological Process GO:0031954 positive regulation of protein autophosphorylation
Biological Process GO:0032874 positive regulation of stress-activated MAPK cascade
Biological Process GO:0046777 protein autophosphorylation
Biological Process GO:0006612 protein targeting to membrane
Biological Process GO:0032956 regulation of actin cytoskeleton organization
Biological Process GO:0001558 regulation of cell growth
Biological Process GO:0008360 regulation of cell shape
Biological Process GO:0023014 signal transduction by protein phosphorylation
Biological Process GO:0051403 stress-activated MAPK cascade
Biological Process GO:0031098 stress-activated protein kinase signaling cascade
molecular function GO:0005524 ATP binding
molecular function GO:0004709 MAP kinase kinase kinase activity
molecular function GO:0031434 mitogen-activated protein kinase kinase binding
molecular function GO:0038191 neuropilin binding
molecular function GO:0004674 protein serine/threonine kinase activity
molecular function GO:0048156 tau protein binding
molecular function GO:0050321 tau-protein kinase activity
cellular component GO:0015629 actin cytoskeleton
cellular component GO:0030424 axon
cellular component GO:0044295 axonal growth cone
cellular component GO:0005737 cytoplasm
cellular component GO:0031410 cytoplasmic vesicle
cellular component GO:0030659 cytoplasmic vesicle membrane
cellular component GO:0005829 cytosol
cellular component GO:0044294 dendritic growth cone
cellular component GO:0016021 integral component of membrane
cellular component GO:0043005 neuron projection
cellular component GO:0005730 nucleolus
cellular component GO:0005654 nucleoplasm
cellular component GO:0043235 receptor complex
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0003467 BXGD000194 Anxiety Behavior and Behavior Mechanisms
C0003469 BXGD000195 Anxiety Disorders Mental Disorders
C0004352 BXGD000269 Autistic Disorder Mental Disorders
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0011265 BXGD000708 Presenile dementia Nervous System Diseases; Mental Disorders
C0021704 BXGD001510 Intelligence Behavior and Behavior Mechanisms
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0033975 BXGD002447 Psychotic Disorders Mental Disorders
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0152013 BXGD003516 Adenocarcinoma of lung (disorder) Neoplasms
C0205682 BXGD004105 Waist-Hip Ratio
C0333463 BXGD006954 Senile Plaques Pathological Conditions, Signs and Symptoms
C0398686 BXGD008215 Primary immune deficiency disorder Immune System Diseases
C0497327 BXGD009061 Dementia Nervous System Diseases; Mental Disorders
C0524528 BXGD009229 Pervasive Development Disorder Mental Disorders
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C1269955 BXGD012005 Tumor Cell Invasion
C1305855 BXGD012348 Body mass index
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1510586 BXGD013176 Autism Spectrum Disorders Mental Disorders
C1535926 BXGD013322 Neurodevelopmental Disorders Mental Disorders
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0012352 Chelerythrine 348.12
BXGC0042376 Picropodophyllotoxin 414.13
BXGC0044857 Sp-600125 220.06
BXGC0045254 Sb-202190 331.11
BXGC0047692 Gefitinib 446.15
BXGC0050099 (2E,5S,6S,8Z,11S)-5,6,15-Trihydroxy-17-Methoxy-11-Methyl-12-Oxabicyclo[12.4.0]Octadeca-1(14),2,8,15,17-Pentaene-7,13-Dione 362.14
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein