Showing entry for Endometrial adenocarcinoma


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD011769
Disease NameEndometrial adenocarcinoma
Disease CUI IdC1153706
MeSH Codes C04   C13  
Disease Class NameNeoplasms; Female Urogenital Diseases and Pregnancy Complications
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7   DOID:14566  
Disease Ontology Class Namedisease of anatomical entity; disease of cellular proliferation
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A0A024RAV5 BXGT000013 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b 3845 unreviewed
O00182 BXGT003889 Galectin-9 3965 reviewed Signaling
O00459 BXGT003924 Phosphatidylinositol 3-kinase regulatory subunit beta 5296 reviewed Enzyme modulator
O00755 BXGT003945 Protein Wnt-7a 7476 reviewed Signaling
O15374 BXGT004157 Monocarboxylate transporter 5 9122 reviewed Transporter
O15427 BXGT004167 Monocarboxylate transporter 4 9123 reviewed Transporter
O43570 BXGT004601 Carbonic anhydrase 12 771 reviewed
O94813 BXGT005337 Slit homolog 2 protein 9353 reviewed
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P00918 BXGT005690 Carbonic anhydrase 2 760 reviewed
P01112 BXGT005732 GTPase HRas 3265 reviewed Enzyme modulator
P01116 BXGT005733 GTPase KRas 3845 reviewed Enzyme modulator
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01833 BXGT005788 Polymeric immunoglobulin receptor 5284 reviewed
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P04278 BXGT006182 Sex hormone-binding globulin 6462 reviewed
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 2064 reviewed Kinase
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P05231 BXGT006345 Interleukin-6 3569 reviewed
P06213 BXGT006425 Insulin receptor 3643 reviewed Kinase
P06401 BXGT006436 Progesterone receptor 5241 reviewed Nuclear receptor
P06730 BXGT006487 Eukaryotic translation initiation factor 4E 1977 reviewed Nucleic acid binding
P06731 BXGT006488 Carcinoembryonic antigen-related cell adhesion molecule 5 1048 reviewed
P07333 BXGT006602 Macrophage colony-stimulating factor 1 receptor 1436 reviewed Kinase
P07339 BXGT006604 Cathepsin D 1509 reviewed Enzyme
P08134 BXGT006728 Rho-related GTP-binding protein RhoC 389 reviewed Enzyme modulator
P08473 BXGT006773 Neprilysin 4311 reviewed Enzyme
P08686 BXGT006813 Steroid 21-hydroxylase 1589 reviewed
P08833 BXGT006827 Insulin-like growth factor-binding protein 1 3484 reviewed Enzyme modulator
P09038 BXGT006851 Fibroblast growth factor 2 2247 reviewed Signaling
P09382 BXGT006882 Galectin-1 3956 reviewed Signaling
P09455 BXGT006890 Retinol-binding protein 1 5947 reviewed
P09466 BXGT006892 Glycodelin 5047 reviewed Enzyme
P09874 BXGT006934 Poly [ADP-ribose] polymerase 1 142 reviewed
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P11511 BXGT007717 Aromatase 1588 reviewed Enzyme
P11802 BXGT007750 Cyclin-dependent kinase 4 1019 reviewed Kinase
P12004 BXGT007766 Proliferating cell nuclear antigen 5111 reviewed Nucleic acid binding
P12830 BXGT007852 Cadherin-1 999 reviewed
P13501 BXGT007917 C-C motif chemokine 5 6352 reviewed Signaling
P14061 BXGT007979 Estradiol 17-beta-dehydrogenase 1 3292 reviewed Enzyme
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P14921 BXGT008068 Protein C-ets-1 2113 reviewed Transcription factor
P15056 BXGT008075 Serine/threonine-protein kinase B-raf 673 reviewed Kinase
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P16144 BXGT008200 Integrin beta-4 3691 reviewed Receptor
P19634 BXGT008504 Sodium/hydrogen exchanger 1 6548 reviewed Transporter
P19883 BXGT008528 Follistatin 10468 reviewed Enzyme modulator
P21802 BXGT008691 Fibroblast growth factor receptor 2 2263 reviewed Kinase
P22083 BXGT008727 Alpha-(1,3)-fucosyltransferase 4 2526 reviewed Enzyme
P22352 BXGT008758 Glutathione peroxidase 3 2878 reviewed Enzyme
P23284 BXGT008845 Peptidyl-prolyl cis-trans isomerase B 5479 reviewed
P24385 BXGT008965 G1/S-specific cyclin-D1 595 reviewed Enzyme modulator
P25025 BXGT009006 C-X-C chemokine receptor type 2 3579 reviewed G-protein coupled receptor
P27361 BXGT009176 Mitogen-activated protein kinase 3 5595 reviewed Kinase
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P29320 BXGT009332 Ephrin type-A receptor 3 2042 reviewed Kinase
P29323 BXGT009334 Ephrin type-B receptor 2 2048 reviewed Kinase
P30556 BXGT009441 Type-1 angiotensin II receptor 185 reviewed G-protein coupled receptor
P30989 BXGT009492 Neurotensin receptor type 1 4923 reviewed G-protein coupled receptor
P31260 BXGT009519 Homeobox protein Hox-A10 3206 reviewed
P31350 BXGT009526 Ribonucleoside-diphosphate reductase subunit M2 6241 reviewed Enzyme
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35408 BXGT009828 Prostaglandin E2 receptor EP4 subtype 5734 reviewed G-protein coupled receptor
P35442 BXGT009832 Thrombospondin-2 7058 reviewed
P35613 BXGT009856 Basigin 682 reviewed
P36897 BXGT009941 TGF-beta receptor type-1 7046 reviewed Kinase
P38936 BXGT010074 Cyclin-dependent kinase inhibitor 1 1026 reviewed
P39900 BXGT010148 Macrophage metalloelastase 4321 reviewed Enzyme
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P42330 BXGT010301 Aldo-keto reductase family 1 member C3 8644 reviewed Enzyme
P43246 BXGT010371 DNA mismatch repair protein Msh2 4436 reviewed Nucleic acid binding
P46531 BXGT010526 Neurogenic locus notch homolog protein 1 4851 reviewed
P48061 BXGT010616 Stromal cell-derived factor 1 6387 reviewed
P49327 BXGT010694 Fatty acid synthase 2194 reviewed Enzyme
P49763 BXGT010737 Placenta growth factor 5228 reviewed Signaling
P50281 BXGT010788 Matrix metalloproteinase-14 4323 reviewed Enzyme
P51532 BXGT010852 Transcription activator BRG1 6597 reviewed Epigenetic regulator
P51684 BXGT010880 C-C chemokine receptor type 6 1235 reviewed G-protein coupled receptor
P52701 BXGT010943 DNA mismatch repair protein Msh6 2956 reviewed Nucleic acid binding
P52789 BXGT010954 Hexokinase-2 3099 reviewed Kinase
P52799 BXGT010956 Ephrin-B2 1948 reviewed Signaling
P53355 BXGT010985 Death-associated protein kinase 1 1612 reviewed Kinase
P54760 BXGT011075 Ephrin type-B receptor 4 2050 reviewed Kinase
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P61073 BXGT011352 C-X-C chemokine receptor type 4 7852 reviewed G-protein coupled receptor
P78556 BXGT011849 C-C motif chemokine 20 6364 reviewed Signaling
Q00987 BXGT012559 E3 ubiquitin-protein ligase Mdm2 4193 reviewed Nucleic acid binding
Q01650 BXGT012603 Large neutral amino acids transporter small subunit 1 8140 reviewed Transporter
Q02790 BXGT012672 Peptidyl-prolyl cis-trans isomerase FKBP4 2288 reviewed Enzyme
Q03181 BXGT012701 Peroxisome proliferator-activated receptor delta 5467 reviewed Nuclear receptor
Q07812 BXGT012940 Apoptosis regulator BAX 581 reviewed Signaling
Q12778 BXGT013263 Forkhead box protein O1 2308 reviewed
Q13133 BXGT013315 Oxysterols receptor LXR-alpha 10062 reviewed Nuclear receptor
Q13451 BXGT013356 Peptidyl-prolyl cis-trans isomerase FKBP5 2289 reviewed Enzyme
Q13705 BXGT013393 Activin receptor type-2B 93 reviewed Kinase
Q15848 BXGT013609 Adiponectin 9370 reviewed
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q16790 BXGT013670 Carbonic anhydrase 9 768 reviewed
Q16828 BXGT013676 Dual specificity protein phosphatase 6 1848 reviewed
Q16874 BXGT013685 Cytochrome P450 21-hydroxylase 1589 unreviewed
Q92731 BXGT019366 Estrogen receptor beta 2100 reviewed Nuclear receptor
Q99519 BXGT019928 Sialidase-1 4758 reviewed Enzyme
Q99816 BXGT019966 Tumor susceptibility gene 101 protein 7251 reviewed Enzyme
Q9H0H5 BXGT020436 Rac GTPase-activating protein 1 29127 reviewed Enzyme modulator
Q9UHI8 BXGT021701 A disintegrin and metalloproteinase with thrombospondin motifs 1 9510 reviewed Enzyme
Q9UIQ6 BXGT021721 Leucyl-cystinyl aminopeptidase 4012 reviewed Enzyme
Q9Y5W5 BXGT022303 Wnt inhibitory factor 1 11197 reviewed Calcium-binding protein
P00738 BXGT022874 Haptoglobin 3240 reviewed Enzyme
P25054 BXGT022961 Adenomatous polyposis coli protein 324 reviewed
O14793 BXGT023280 Growth/differentiation factor 8 2660 reviewed Signaling
Q99958 BXGT023732 Forkhead box protein C2 2303 reviewed Transcription factor
P20809 BXGT025043 Interleukin-11 3589 reviewed
P00403 BXGT026137 Cytochrome c oxidase subunit 2 4513 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease