adisease

Showing entry for Plaque, Amyloid

General Disease Information
BXGD Id	BXGD018109
Disease Name	Plaque, Amyloid
Disease CUI Id	C2936349
MeSH Codes	C23
Disease Class Name	Pathological Conditions, Signs and Symptoms
Semantic Type	Acquired Abnormality
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
F7VJQ1	BXGT003310	Alternative prion protein	5621	reviewed
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O00329	BXGT003909	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	5293	reviewed	Kinase
O14672	BXGT004081	Disintegrin and metalloproteinase domain-containing protein 10	102	reviewed
O15455	BXGT004171	Toll-like receptor 3	7098	reviewed	Receptor
O75923	BXGT005166	Dysferlin	8291	reviewed	Transporter
O95477	BXGT005383	Phospholipid-transporting ATPase ABCA1	19	reviewed	Transporter
P00736	BXGT005632	Complement C1r subcomponent	715	reviewed	Enzyme
P00747	BXGT005639	Plasminogen	5340	reviewed	Enzyme
P01008	BXGT005713	Antithrombin-III	462	reviewed	Enzyme modulator
P01011	BXGT005715	Alpha-1-antichymotrypsin	12	reviewed	Enzyme modulator
P01019	BXGT005717	Angiotensinogen	183	reviewed	Enzyme modulator
P01034	BXGT005721	Cystatin-C	1471	reviewed
P02647	BXGT005908	Apolipoprotein A-I	335	reviewed
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P02655	BXGT005912	Apolipoprotein C-II	344	reviewed
P02743	BXGT005937	Serum amyloid P-component	325	reviewed
P02766	BXGT005953	Transthyretin	7276	reviewed	Transporter
P02795	BXGT005968	Metallothionein-2	4502	reviewed
P04156	BXGT006156	Major prion protein	5621	reviewed
P04271	BXGT006177	Protein S100-B	6285	reviewed	Calcium-binding protein
P04792	BXGT006264	Heat shock protein beta-1	3315	reviewed
P05067	BXGT006306	Amyloid-beta precursor protein	351	reviewed	Enzyme modulator
P05164	BXGT006333	Myeloperoxidase	4353	reviewed	Enzyme
P06396	BXGT006435	Gelsolin	2934	reviewed	Cellular structure
P07339	BXGT006604	Cathepsin D	1509	reviewed	Enzyme
P07858	BXGT006689	Cathepsin B	1508	reviewed	Enzyme
P08473	BXGT006773	Neprilysin	4311	reviewed	Enzyme
P08575	BXGT006793	Receptor-type tyrosine-protein phosphatase C	5788	reviewed	Enzyme
P09104	BXGT006856	Gamma-enolase	2026	reviewed	Enzyme
P09466	BXGT006892	Glycodelin	5047	reviewed	Enzyme
P09917	BXGT006941	Arachidonate 5-lipoxygenase	240	reviewed	Enzyme
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P10636	BXGT007596	Microtubule-associated protein tau	4137	reviewed
P10997	BXGT007643	Islet amyloid polypeptide	3375	reviewed	Signaling
P11137	BXGT007656	Microtubule-associated protein 2	4133	reviewed
P17655	BXGT008325	Calpain-2 catalytic subunit	824	reviewed	Enzyme
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	1131	reviewed	G-protein coupled receptor
P20702	BXGT008592	Integrin alpha-X	3687	reviewed
P22303	BXGT008751	Acetylcholinesterase	43	reviewed	Enzyme
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P25713	BXGT009062	Metallothionein-3	4504	reviewed
P27338	BXGT009172	Amine oxidase [flavin-containing] B	4129	reviewed
P30536	BXGT009435	Translocator protein	706	reviewed
P30556	BXGT009441	Type-1 angiotensin II receptor	185	reviewed	G-protein coupled receptor
P37840	BXGT010015	Alpha-synuclein	6622	reviewed	Transporter
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P42338	BXGT010303	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	5291	reviewed	Kinase
P42574	BXGT010317	Caspase-3	836	reviewed	Enzyme
P42858	BXGT010341	Huntingtin	3064	reviewed
P43220	BXGT010367	Glucagon-like peptide 1 receptor	2740	reviewed	G-protein coupled receptor
P43235	BXGT010368	Cathepsin K	1513	reviewed	Enzyme
P43681	BXGT010407	Neuronal acetylcholine receptor subunit alpha-4	1137	reviewed	Ion channel
P48736	BXGT010658	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	5294	reviewed	Kinase
P49286	BXGT010691	Melatonin receptor type 1B	4544	reviewed	G-protein coupled receptor
P49768	BXGT010740	Presenilin-1	5663	reviewed	Enzyme
P56817	BXGT011200	Beta-secretase 1	23621	reviewed	Enzyme
P60709	BXGT011322	Actin, cytoplasmic 1	60	reviewed	Cellular structure
P60880	BXGT011335	Synaptosomal-associated protein 25	6616	reviewed	Transporter
P61626	BXGT011382	Lysozyme C	4069	reviewed
P61769	BXGT011383	Beta-2-microglobulin	567	reviewed	Immune response
P63096	BXGT011496	Guanine nucleotide-binding protein G(i) subunit alpha-1	2770	reviewed	Enzyme modulator
Q04609	BXGT012768	Glutamate carboxypeptidase 2	2346	reviewed	Enzyme
Q05586	BXGT012826	Glutamate receptor ionotropic, NMDA 1	2902	reviewed	Ion channel
Q13315	BXGT013339	Serine-protein kinase ATM	472	reviewed	Kinase
Q14114	BXGT013441	Low-density lipoprotein receptor-related protein 8	7804	reviewed
Q15109	BXGT013537	Advanced glycosylation end product-specific receptor	177	reviewed	Receptor
Q15582	BXGT013581	Transforming growth factor-beta-induced protein ig-h3	7045	reviewed	Signaling
Q96P20	BXGT019704	NACHT, LRR and PYD domains-containing protein 3	114548	reviewed
Q99519	BXGT019928	Sialidase-1	4758	reviewed	Enzyme
Q99714	BXGT019954	3-hydroxyacyl-CoA dehydrogenase type-2	3028	reviewed	Enzyme
Q9NRF2	BXGT021185	SH2B adapter protein 1	25970	reviewed
Q9P2R7	BXGT021304	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	8803	reviewed	Enzyme
Q9Y6A2	BXGT022324	Cholesterol 24-hydroxylase	10858	reviewed	Enzyme
O60502	BXGT023392	Protein O-GlcNAcase	10724	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}