Showing entry for Heart failure with preserved ejection fraction [HFpEF]


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD022972
Disease NameHeart failure with preserved ejection fraction [HFpEF]
Disease CUI IdC4509226
MeSH Codes   
Disease Class Name
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O14791 BXGT004101 Apolipoprotein L1 8542 reviewed Transporter
O43451 BXGT004594 Maltase-glucoamylase, intestinal 8972 reviewed Enzyme
O43524 BXGT004599 Forkhead box protein O3 2309 reviewed
O75390 BXGT005123 Citrate synthase, mitochondrial 1431 reviewed Enzyme
O75460 BXGT005127 Serine/threonine-protein kinase/endoribonuclease IRE1 2081 reviewed Kinase
O75469 BXGT005128 Nuclear receptor subfamily 1 group I member 2 8856 reviewed Nuclear receptor
O76074 BXGT005174 cGMP-specific 3',5'-cyclic phosphodiesterase 8654 reviewed
O94925 BXGT005342 Glutaminase kidney isoform, mitochondrial 2744 reviewed Enzyme
P00797 BXGT005658 Renin 5972 reviewed Enzyme
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P01130 BXGT005735 Low-density lipoprotein receptor 3949 reviewed
P01275 BXGT005747 Glucagon 2641 reviewed
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02763 BXGT005951 Alpha-1-acid glycoprotein 1 5004 reviewed
P02766 BXGT005953 Transthyretin 7276 reviewed Transporter
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P03950 BXGT006116 Angiogenin 283 reviewed
P05091 BXGT006312 Aldehyde dehydrogenase, mitochondrial 217 reviewed Enzyme
P05107 BXGT006316 Integrin beta-2 3689 reviewed Receptor
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P07101 BXGT006547 Tyrosine 3-monooxygenase 7054 reviewed
P07741 BXGT006666 Adenine phosphoribosyltransferase 353 reviewed
P08235 BXGT006751 Mineralocorticoid receptor 4306 reviewed Nuclear receptor
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08473 BXGT006773 Neprilysin 4311 reviewed Enzyme
P08833 BXGT006827 Insulin-like growth factor-binding protein 1 3484 reviewed Enzyme modulator
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P14410 BXGT008009 Sucrase-isomaltase, intestinal 6476 reviewed Enzyme
P15090 BXGT008079 Fatty acid-binding protein, adipocyte 2167 reviewed
P15151 BXGT008089 Poliovirus receptor 5817 reviewed
P17861 BXGT008348 X-box-binding protein 1 7494 reviewed
P17931 BXGT008356 Galectin-3 3958 reviewed Signaling
P19429 BXGT008479 Troponin I, cardiac muscle 7137 reviewed Cellular structure
P24530 BXGT008975 Endothelin receptor type B 1910 reviewed G-protein coupled receptor
P25116 BXGT009025 Proteinase-activated receptor 1 2149 reviewed G-protein coupled receptor
P25705 BXGT009060 ATP synthase subunit alpha, mitochondrial 498 reviewed Transporter
P27487 BXGT009187 Dipeptidyl peptidase 4 1803 reviewed Enzyme
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P30542 BXGT009436 Adenosine receptor A1 134 reviewed G-protein coupled receptor
P31639 BXGT009556 Sodium/glucose cotransporter 2 6524 reviewed Transporter
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P39060 BXGT010088 Collagen alpha-1(XVIII) chain 80781 reviewed
P43220 BXGT010367 Glucagon-like peptide 1 receptor 2740 reviewed G-protein coupled receptor
P55085 BXGT011104 Proteinase-activated receptor 2 2150 reviewed G-protein coupled receptor
P55263 BXGT011115 Adenosine kinase 132 reviewed Kinase
P83916 BXGT012025 Chromobox protein homolog 1 10951 reviewed Epigenetic regulator
Q13976 BXGT013409 cGMP-dependent protein kinase 1 5592 reviewed Kinase
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q8WZ42 BXGT019023 Titin 7273 reviewed Kinase
Q9H9B1 BXGT020501 Histone-lysine N-methyltransferase EHMT1 79813 reviewed Epigenetic regulator
Q9NTG7 BXGT021211 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 23410 reviewed Epigenetic regulator
O95140 BXGT024482 Mitofusin-2 9927 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease