Showing entry for Amyotrophic Lateral Sclerosis, Familial


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD023469
Disease NameAmyotrophic Lateral Sclerosis, Familial
Disease CUI IdC4551993
MeSH Codes C18   C10  
Disease Class NameNutritional and Metabolic Diseases; Nervous System Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
F7VJQ1 BXGT003310 Alternative prion protein 5621 reviewed
O00755 BXGT003945 Protein Wnt-7a 7476 reviewed Signaling
O14618 BXGT004076 Copper chaperone for superoxide dismutase 9973 reviewed Enzyme
O14727 BXGT004084 Apoptotic protease-activating factor 1 317 reviewed
O14782 BXGT004098 Kinesin-like protein KIF3C 3797 reviewed Cellular structure
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] 6647 reviewed Enzyme
P01011 BXGT005715 Alpha-1-antichymotrypsin 12 reviewed Enzyme modulator
P01034 BXGT005721 Cystatin-C 1471 reviewed
P01100 BXGT005727 Proto-oncogene c-Fos 2353 reviewed Transcription factor
P01130 BXGT005735 Low-density lipoprotein receptor 3949 reviewed
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P02511 BXGT005885 Alpha-crystallin B chain 1410 reviewed
P04040 BXGT006132 Catalase 847 reviewed Enzyme
P04156 BXGT006156 Major prion protein 5621 reviewed
P04179 BXGT006163 Superoxide dismutase [Mn], mitochondrial 6648 reviewed Enzyme
P04839 BXGT006273 Cytochrome b-245 heavy chain 1536 reviewed Ion channel
P05067 BXGT006306 Amyloid-beta precursor protein 351 reviewed Enzyme modulator
P07203 BXGT006566 Glutathione peroxidase 1 2876 reviewed Enzyme
P07237 BXGT006576 Protein disulfide-isomerase 5034 reviewed
P07339 BXGT006604 Cathepsin D 1509 reviewed Enzyme
P07737 BXGT006663 Profilin-1 5216 reviewed
P08670 BXGT006810 Vimentin 7431 reviewed
P09382 BXGT006882 Galectin-1 3956 reviewed Signaling
P09651 BXGT006913 Heterogeneous nuclear ribonucleoprotein A1 3178 reviewed
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10599 BXGT007583 Thioredoxin 7295 reviewed
P10636 BXGT007596 Microtubule-associated protein tau 4137 reviewed
P10909 BXGT007630 Clusterin 1191 reviewed
P14867 BXGT008061 Gamma-aminobutyric acid receptor subunit alpha-1 2554 reviewed Ion channel
P17861 BXGT008348 X-box-binding protein 1 7494 reviewed
P19793 BXGT008515 Retinoic acid receptor RXR-alpha 6256 reviewed Nuclear receptor
P22102 BXGT008731 Trifunctional purine biosynthetic protein adenosine-3 2618 reviewed Enzyme
P27169 BXGT009161 Serum paraoxonase/arylesterase 1 5444 reviewed
P29466 BXGT009349 Caspase-1 834 reviewed Enzyme
P30041 BXGT009393 Peroxiredoxin-6 9588 reviewed Enzyme
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P32119 BXGT009600 Peroxiredoxin-2 7001 reviewed Enzyme
P35613 BXGT009856 Basigin 682 reviewed
P35858 BXGT009876 Insulin-like growth factor-binding protein complex acid labile subunit 3483 reviewed Receptor
P37840 BXGT010015 Alpha-synuclein 6622 reviewed Transporter
P39086 BXGT010093 Glutamate receptor ionotropic, kainate 1 2897 reviewed Ion channel
P42263 BXGT010295 Glutamate receptor 3 2892 reviewed Ion channel
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P49662 BXGT010724 Caspase-4 837 reviewed Enzyme
P52333 BXGT010928 Tyrosine-protein kinase JAK3 3718 reviewed Kinase
P55072 BXGT011103 Transitional endoplasmic reticulum ATPase 7415 reviewed
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P68366 BXGT011595 Tubulin alpha-4A chain 7277 reviewed Cellular structure
P98170 BXGT012231 E3 ubiquitin-protein ligase XIAP 331 reviewed Enzyme modulator
Q00613 BXGT012540 Heat shock factor protein 1 3297 reviewed Transcription factor
Q01082 BXGT012567 Spectrin beta chain, non-erythrocytic 1 6711 reviewed
Q01959 BXGT012624 Sodium-dependent dopamine transporter 6531 reviewed Transporter
Q03393 BXGT012711 6-pyruvoyl tetrahydrobiopterin synthase 5805 reviewed
Q07817 BXGT012941 Bcl-2-like protein 1 598 reviewed Signaling
Q13009 BXGT013305 T-lymphoma invasion and metastasis-inducing protein 1 7074 reviewed
Q13148 BXGT013318 TAR DNA-binding protein 43 23435 reviewed
Q14203 BXGT013455 Dynactin subunit 1 1639 reviewed Chaperone
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q16698 BXGT013659 2,4-dienoyl-CoA reductase, mitochondrial 1666 reviewed Enzyme
Q16881 BXGT013688 Thioredoxin reductase 1, cytoplasmic 7296 reviewed Enzyme
Q92793 BXGT019374 CREB-binding protein 1387 reviewed
Q99523 BXGT019929 Sortilin 6272 reviewed Transporter
Q99700 BXGT019949 Ataxin-2 6311 reviewed Nucleic acid binding
Q9UHD2 BXGT021697 Serine/threonine-protein kinase TBK1 29110 reviewed Kinase
Q9Y223 BXGT022207 Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase 10020 reviewed Enzyme
Q9Y243 BXGT022214 RAC-gamma serine/threonine-protein kinase 10000 reviewed Kinase
P17535 BXGT023437 Transcription factor jun-D 3727 reviewed Transcription factor
Q9BYE2 BXGT024631 Transmembrane protease serine 13 84000 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease