Showing entry for Metastatic Renal Cell Carcinoma


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD023763
Disease NameMetastatic Renal Cell Carcinoma
Disease CUI IdC4721698
MeSH Codes C04   C13   C12  
Disease Class NameNeoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O14638 BXGT004077 Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 5169 reviewed Enzyme
O14965 BXGT004117 Aurora kinase A 6790 reviewed Kinase
O60462 BXGT004876 Neuropilin-2 8828 reviewed
O60494 BXGT004879 Cubilin 8029 reviewed
O75385 BXGT005121 Serine/threonine-protein kinase ULK1 8408 reviewed Kinase
O95631 BXGT005387 Netrin-1 9423 reviewed Enzyme modulator
P01589 BXGT005773 Interleukin-2 receptor subunit alpha 3559 reviewed Receptor
P01909 BXGT005815 HLA class II histocompatibility antigen, DQ alpha 1 chain 3117 reviewed Immune response
P01911 BXGT005816 HLA class II histocompatibility antigen, DRB1-15 beta chain 3123 reviewed Immune response
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02766 BXGT005953 Transthyretin 7276 reviewed Transporter
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P04083 BXGT006147 Annexin A1 301 reviewed
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04818 BXGT006269 Thymidylate synthase 7298 reviewed Enzyme
P05120 BXGT006319 Plasminogen activator inhibitor 2 5055 reviewed Enzyme modulator
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05362 BXGT006350 Intercellular adhesion molecule 1 3383 reviewed
P07741 BXGT006666 Adenine phosphoribosyltransferase 353 reviewed
P08034 BXGT006716 Gap junction beta-1 protein 2705 reviewed Cell-cell junction
P08133 BXGT006727 Annexin A6 309 reviewed
P08183 BXGT006741 ATP-dependent translocase ABCB1 5243 reviewed Transporter
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08473 BXGT006773 Neprilysin 4311 reviewed Enzyme
P08581 BXGT006794 Hepatocyte growth factor receptor 4233 reviewed Kinase
P08670 BXGT006810 Vimentin 7431 reviewed
P08684 BXGT006812 Cytochrome P450 3A4 1576 reviewed Enzyme
P09038 BXGT006851 Fibroblast growth factor 2 2247 reviewed Signaling
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P14902 BXGT008065 Indoleamine 2,3-dioxygenase 1 3620 reviewed
P15531 BXGT008136 Nucleoside diphosphate kinase A 4830 reviewed Kinase
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P16410 BXGT008224 Cytotoxic T-lymphocyte protein 4 1493 reviewed
P16442 BXGT008227 Histo-blood group ABO system transferase 28 reviewed Enzyme
P17948 BXGT008358 Vascular endothelial growth factor receptor 1 2321 reviewed Kinase
P19320 BXGT008470 Vascular cell adhesion protein 1 7412 reviewed
P20815 BXGT008604 Cytochrome P450 3A5 1577 reviewed Enzyme
P21730 BXGT008687 C5a anaphylatoxin chemotactic receptor 1 728 reviewed G-protein coupled receptor
P21802 BXGT008691 Fibroblast growth factor receptor 2 2263 reviewed Kinase
P22309 BXGT008753 UDP-glucuronosyltransferase 1-1 54658 reviewed
P24298 BXGT008960 Alanine aminotransferase 1 2875 reviewed Enzyme
P25024 BXGT009005 C-X-C chemokine receptor type 1 3577 reviewed G-protein coupled receptor
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P29317 BXGT009331 Ephrin type-A receptor 2 1969 reviewed Kinase
P29323 BXGT009334 Ephrin type-B receptor 2 2048 reviewed Kinase
P30530 BXGT009431 Tyrosine-protein kinase receptor UFO 558 reviewed Kinase
P30613 BXGT009447 Pyruvate kinase PKLR 5313 reviewed Kinase
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P33681 BXGT009739 T-lymphocyte activation antigen CD80 941 reviewed
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35916 BXGT009881 Vascular endothelial growth factor receptor 3 2324 reviewed Kinase
P35968 BXGT009887 Vascular endothelial growth factor receptor 2 3791 reviewed Kinase
P36888 BXGT009938 Receptor-type tyrosine-protein kinase FLT3 2322 reviewed Kinase
P37023 BXGT009953 Serine/threonine-protein kinase receptor R3 94 reviewed Kinase
P37840 BXGT010015 Alpha-synuclein 6622 reviewed Transporter
P39060 BXGT010088 Collagen alpha-1(XVIII) chain 80781 reviewed
P40337 BXGT010174 von Hippel-Lindau disease tumor suppressor 7428 reviewed Enzyme
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P40933 BXGT010209 Interleukin-15 3600 reviewed
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P42345 BXGT010304 Serine/threonine-protein kinase mTOR 2475 reviewed Kinase
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P49763 BXGT010737 Placenta growth factor 5228 reviewed Signaling
P53396 BXGT010988 ATP-citrate synthase 47 reviewed Enzyme
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P60568 BXGT011315 Interleukin-2 3558 reviewed
P61073 BXGT011352 C-X-C chemokine receptor type 4 7852 reviewed G-protein coupled receptor
P78504 BXGT011844 Protein jagged-1 182 reviewed
Q04609 BXGT012768 Glutamate carboxypeptidase 2 2346 reviewed Enzyme
Q06710 BXGT012887 Paired box protein Pax-8 7849 reviewed
Q13541 BXGT013371 Eukaryotic translation initiation factor 4E-binding protein 1 1978 reviewed Nucleic acid binding
Q15116 BXGT013539 Programmed cell death protein 1 5133 reviewed
Q15848 BXGT013609 Adiponectin 9370 reviewed
Q16790 BXGT013670 Carbonic anhydrase 9 768 reviewed
Q6ZQY3 BXGT016636 Acidic amino acid decarboxylase GADL1 339896 reviewed
Q86SR1 BXGT017600 Polypeptide N-acetylgalactosaminyltransferase 10 55568 reviewed Enzyme
Q86U86 BXGT017611 Protein polybromo-1 55193 reviewed Epigenetic regulator
Q86V24 BXGT017615 Adiponectin receptor protein 2 79602 reviewed Receptor
Q96A70 BXGT019615 Antizyme inhibitor 2 113451 reviewed Enzyme
Q96AZ6 BXGT019621 Interferon-stimulated gene 20 kDa protein 3669 reviewed
Q9BYW2 BXGT020192 Histone-lysine N-methyltransferase SETD2 29072 reviewed Epigenetic regulator
Q9BZS1 BXGT020203 Forkhead box protein P3 50943 reviewed
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9UNQ0 BXGT021792 ATP-binding cassette sub-family G member 2 9429 reviewed Transporter
Q9UM82 BXGT023181 Spermatogenesis-associated protein 2 9825 reviewed
P63167 BXGT024120 Dynein light chain 1, cytoplasmic 8655 reviewed Cellular structure
O60232 BXGT024169 Protein ZNRD2 10534 reviewed
Q96A54 BXGT024681 Adiponectin receptor protein 1 51094 reviewed Receptor
P11836 BXGT025994 B-lymphocyte antigen CD20 931 reviewed Receptor
P19532 BXGT026110 Transcription factor E3 7030 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease