Showing entry for Solute carrier family 2, facilitated glucose transporter member 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT007663
Protein NameSolute carrier family 2, facilitated glucose transporter member 2
Uniport IdP11168
GeneSLC2A2
Gene Id6514
DomainSugar_tr
Pfam PF00083  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
5. Organismal Systems 5.2 Endocrine system hsa04911 Insulin secretion
5. Organismal Systems 5.2 Endocrine system hsa04917 Prolactin signaling pathway
5. Organismal Systems 5.2 Endocrine system hsa04922 Glucagon signaling pathway
6. Human Diseases 6.7 Endocrine and metabolic diseases hsa04930 Type II diabetes mellitus
6. Human Diseases 6.7 Endocrine and metabolic diseases hsa04931 Insulin resistance
6. Human Diseases 6.7 Endocrine and metabolic diseases hsa04950 Maturity onset diabetes of the young
5. Organismal Systems 5.4 Digestive system hsa04973 Carbohydrate digestion and absorption
6. Human Diseases 6.1 Cancers: Overview hsa05230 Central carbon metabolism in cancer
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0005975 carbohydrate metabolic process
Biological Process GO:0070837 dehydroascorbic acid transport
Biological Process GO:0015755 fructose transmembrane transport
Biological Process GO:1904659 glucose transmembrane transport
Biological Process GO:0008645 hexose transmembrane transport
Biological Process GO:0106001 intestinal hexose absorption
Biological Process GO:0050796 regulation of insulin secretion
molecular function GO:0033300 dehydroascorbic acid transmembrane transporter activity
molecular function GO:0055056 D-glucose transmembrane transporter activity
molecular function GO:0005353 fructose transmembrane transporter activity
molecular function GO:0005355 glucose transmembrane transporter activity
cellular component GO:0016324 apical plasma membrane
cellular component GO:0005903 brush border
cellular component GO:0005911 cell-cell junction
cellular component GO:0005737 cytoplasm
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0016020 membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-1266738 Developmental Biology
R-HSA-1430728 Metabolism
R-HSA-163685 Integration of energy metabolism
R-HSA-1643685 Disease
R-HSA-186712 Regulation of beta-cell development
R-HSA-189200 Cellular hexose transport
R-HSA-210745 Regulation of gene expression in beta cells
R-HSA-382551 Transport of small molecules
R-HSA-422356 Regulation of insulin secretion
R-HSA-425407 SLC-mediated transmembrane transport
R-HSA-5619098 Defective SLC2A2 causes Fanconi-Bickel syndrome (FBS)
R-HSA-5619102 SLC transporter disorders
R-HSA-5619115 Disorders of transmembrane transporters
R-HSA-8963676 Intestinal absorption
R-HSA-8963743 Digestion and absorption
R-HSA-8981373 Intestinal hexose absorption
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000731 BXGD000002 Abdomen distended Digestive System Diseases
C0001122 BXGD000023 Acidosis Nutritional and Metabolic Diseases
C0002152 BXGD000104 Alloxan Diabetes Nutritional and Metabolic Diseases; Endocrine System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0011253 BXGD000706 Delusions Behavior and Behavior Mechanisms
C0011334 BXGD000716 Dental caries Stomatognathic Diseases
C0011615 BXGD000738 Dermatitis, Atopic Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Immune System Diseases
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011853 BXGD000752 Diabetes Mellitus, Experimental Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011881 BXGD000760 Diabetic Nephropathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0013336 BXGD000815 Dwarfism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C0013595 BXGD000858 Eczema Skin and Connective Tissue Diseases
C0015544 BXGD001003 Failure to Thrive Pathological Conditions, Signs and Symptoms
C0015624 BXGD001005 Fanconi Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0015695 BXGD001013 Fatty Liver Digestive System Diseases
C0015934 BXGD001026 Fetal Growth Retardation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0016952 BXGD001085 Galactosemias Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0017919 BXGD001150 Glycogen Storage Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0017979 BXGD001159 Glycosuria Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0017980 BXGD001160 Glycosuria, Renal Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0020456 BXGD001392 Hyperglycemia Nutritional and Metabolic Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0020615 BXGD001445 Hypoglycemia Nutritional and Metabolic Diseases
C0020621 BXGD001449 Hypokalemia Nutritional and Metabolic Diseases
C0021655 BXGD001508 Insulin Resistance Nutritional and Metabolic Diseases
C0021670 BXGD001509 insulinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0021828 BXGD001515 Intestinal Atresia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases
C0022638 BXGD001567 Ketosis Nutritional and Metabolic Diseases
C0022658 BXGD001570 Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0024523 BXGD001781 Malabsorption Syndrome Digestive System Diseases; Nutritional and Metabolic Diseases
C0025202 BXGD001832 melanoma Neoplasms
C0025312 BXGD001861 Meningomyelocele Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0025517 BXGD001875 Metabolic Diseases Nutritional and Metabolic Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027794 BXGD002036 Neural Tube Defects Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0038433 BXGD002754 Streptozotocin Diabetes Nutritional and Metabolic Diseases; Endocrine System Diseases
C0042769 BXGD002999 Virus Diseases Infections
C0079731 BXGD003087 B-Cell Lymphomas Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0085207 BXGD003140 Gestational Diabetes Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0085682 BXGD003238 Hypophosphatemia Nutritional and Metabolic Diseases
C0149782 BXGD003365 Squamous cell carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0151747 BXGD003471 Renal tubular disorder Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0151849 BXGD003486 Alkaline phosphatase raised Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0158981 BXGD003914 Neonatal diabetes mellitus Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Endocrine System Diseases
C0201657 BXGD004051 C-reactive protein measurement
C0202236 BXGD004086 Triglycerides measurement
C0221032 BXGD004374 Familial generalized lipodystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0221333 BXGD004441 Hypouricemia Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0232462 BXGD004542 Decrease in appetite Digestive System Diseases; Nervous System Diseases; Mental Disorders
C0242363 BXGD005156 Islet Cell Tumor Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0268186 BXGD005848 Congenital glucose-galactose malabsorption Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Nutritional and Metabolic Diseases
C0268731 BXGD006029 Renal glomerular disease Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0271650 BXGD006227 Impaired glucose tolerance Nutritional and Metabolic Diseases
C0271708 BXGD006244 Fasting Hypoglycemia Nutritional and Metabolic Diseases
C0282201 BXGD006799 Phosphate Diabetes Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0333519 BXGD006958 Caries (morphologic abnormality) Pathological Conditions, Signs and Symptoms
C0334070 BXGD006986 Maturation defect
C0337438 BXGD007159 Glucose measurement
C0341703 BXGD007419 Adult Fanconi syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0342273 BXGD007448 Transient neonatal diabetes mellitus
C0342276 BXGD007449 Maturity onset diabetes mellitus in young Nutritional and Metabolic Diseases; Endocrine System Diseases
C0349588 BXGD007933 Short stature
C0400966 BXGD008266 Non-alcoholic Fatty Liver Disease Digestive System Diseases
C0428568 BXGD008633 Fasting blood glucose measurement
C0495706 BXGD009038 elevated blood glucose level
C0524620 BXGD009236 Metabolic Syndrome X Nutritional and Metabolic Diseases
C0557874 BXGD009444 Global developmental delay
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0858600 BXGD011182 Taste sweet
C0949541 BXGD011578 Hurthle Cell Tumor Neoplasms
C1257931 BXGD011815 Mammary Neoplasms, Human Neoplasms; Skin and Connective Tissue Diseases
C1257958 BXGD011816 Glucose Metabolism Disorders Nutritional and Metabolic Diseases
C1261430 BXGD011853 Fasting blood sugar result
C1273070 BXGD012018 Left ventricular diastolic dysfunction Cardiovascular Diseases
C1278049 BXGD012114 Serum gamma-glutamyl transferase measurement
C1290645 BXGD012193 Dentin bridge Stomatognathic Diseases
C1305855 BXGD012348 Body mass index
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1314665 BXGD012386 Serum alkaline phosphatase raised
C1378050 BXGD012931 Oncocytic Neoplasm
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1510502 BXGD013175 Oxyphilic Adenoma Neoplasms
C1565489 BXGD013401 Renal Insufficiency Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1704375 BXGD013551 Hypophosphatemic Rickets Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C1735903 BXGD013720 Chronic acidosis Nutritional and Metabolic Diseases
C1833104 BXGD013896 DIABETES MELLITUS, PERMANENT NEONATAL Nutritional and Metabolic Diseases; Endocrine System Diseases
C1847501 BXGD014866 Glut1 Deficiency Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C1847868 BXGD014893 Generalized aminoaciduria
C1857395 BXGD015701 De Toni-Debre-Fanconi Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1857657 BXGD015732 Reduced subcutaneous adipose tissue
C1963165 BXGD016685 Malabsorption, CTCAE
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2315100 BXGD017021 Pediatric failure to thrive Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases; Mental Disorders
C2711227 BXGD017478 Steatohepatitis Digestive System Diseases
C2748055 BXGD017583 Hypoinsulinaemia (disorder)
C2919142 BXGD017867 Short Stature, CTCAE
C3245525 BXGD018581 Familial renal glucosuria Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C3266262 BXGD018600 Multiple Chronic Conditions Pathological Conditions, Signs and Symptoms
C3472608 BXGD018921 Micropapillary carcinoma
C3495427 BXGD018984 Fanconi-Bickel Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C3536983 BXGD019078 Familial Hypophosphatemic Rickets Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Musculoskeletal Diseases; Male Urogenital Diseases
C3539878 BXGD019087 Triple Negative Breast Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C3714745 BXGD019427 Malabsorption Digestive System Diseases
C3887638 BXGD019906 Failure to thrive in infant Pathological Conditions, Signs and Symptoms
C3887650 BXGD019911 Adult Rickets Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C4021643 BXGD020716 Impairment of galactose metabolism
C4529962 BXGD023178 Fatty Liver Disease
C4703555 BXGD023658 Decreased waist to hip ratio
C4704874 BXGD023682 Mammary Carcinoma, Human Neoplasms; Skin and Connective Tissue Diseases
C4722518 BXGD023806 Triple-Negative Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0005683 Quercetin 302.24
BXGC0006306 Myricetin 318.24
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein