Showing entry for Streptozotocin Diabetes


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD002754
Disease NameStreptozotocin Diabetes
Disease CUI IdC0038433
MeSH Codes C18   C19  
Disease Class NameNutritional and Metabolic Diseases; Endocrine System Diseases
Semantic TypeExperimental Model of Disease
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O43524 BXGT004599 Forkhead box protein O3 2309 reviewed
O95831 BXGT005399 Apoptosis-inducing factor 1, mitochondrial 9131 reviewed Enzyme
P00390 BXGT005526 Glutathione reductase, mitochondrial 2936 reviewed Enzyme
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] 6647 reviewed Enzyme
P00797 BXGT005658 Renin 5972 reviewed Enzyme
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P03886 BXGT006108 NADH-ubiquinone oxidoreductase chain 1 4535 reviewed Enzyme
P04040 BXGT006132 Catalase 847 reviewed Enzyme
P04179 BXGT006163 Superoxide dismutase [Mn], mitochondrial 6648 reviewed Enzyme
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04798 BXGT006265 Cytochrome P450 1A1 1543 reviewed Enzyme
P04839 BXGT006273 Cytochrome b-245 heavy chain 1536 reviewed Ion channel
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P05164 BXGT006333 Myeloperoxidase 4353 reviewed Enzyme
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05362 BXGT006350 Intercellular adhesion molecule 1 3383 reviewed
P06213 BXGT006425 Insulin receptor 3643 reviewed Kinase
P06703 BXGT006477 Protein S100-A6 6277 reviewed Calcium-binding protein
P07203 BXGT006566 Glutathione peroxidase 1 2876 reviewed Enzyme
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 1129 reviewed G-protein coupled receptor
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08842 BXGT006830 Steryl-sulfatase 412 reviewed Enzyme
P09601 BXGT006909 Heme oxygenase 1 3162 reviewed
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10997 BXGT007643 Islet amyloid polypeptide 3375 reviewed Signaling
P11168 BXGT007663 Solute carrier family 2, facilitated glucose transporter member 2 6514 reviewed Transporter
P11474 BXGT007710 Steroid hormone receptor ERR1 2101 reviewed Nuclear receptor
P11498 BXGT007714 Pyruvate carboxylase, mitochondrial 5091 reviewed Enzyme
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P13945 BXGT007972 Beta-3 adrenergic receptor 155 reviewed G-protein coupled receptor
P14598 BXGT008024 Neutrophil cytosol factor 1 653361 reviewed
P14672 BXGT008037 Solute carrier family 2, facilitated glucose transporter member 4 6517 reviewed Transporter
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P15559 BXGT008139 NAD(P)H dehydrogenase [quinone] 1 1728 reviewed
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P17252 BXGT008294 Protein kinase C alpha type 5578 reviewed Kinase
P18847 BXGT008431 Cyclic AMP-dependent transcription factor ATF-3 467 reviewed Transcription factor
P19367 BXGT008476 Hexokinase-1 3098 reviewed Kinase
P19438 BXGT008480 Tumor necrosis factor receptor superfamily member 1A 7132 reviewed
P19634 BXGT008504 Sodium/hydrogen exchanger 1 6548 reviewed Transporter
P20813 BXGT008603 Cytochrome P450 2B6 1555 reviewed
P20815 BXGT008604 Cytochrome P450 3A5 1577 reviewed Enzyme
P28845 BXGT009297 Corticosteroid 11-beta-dehydrogenase isozyme 1 3290 reviewed
P29474 BXGT009352 Nitric oxide synthase, endothelial 4846 reviewed
P30613 BXGT009447 Pyruvate kinase PKLR 5313 reviewed Kinase
P33121 BXGT009692 Long-chain-fatty-acid--CoA ligase 1 2180 reviewed Enzyme
P35228 BXGT009800 Nitric oxide synthase, inducible 4843 reviewed
P35348 BXGT009814 Alpha-1A adrenergic receptor 148 reviewed G-protein coupled receptor
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35557 BXGT009846 Glucokinase 2645 reviewed Kinase
P35558 BXGT009847 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] 5105 reviewed Kinase
P36956 BXGT009947 Sterol regulatory element-binding protein 1 6720 reviewed
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P46663 BXGT010531 B1 bradykinin receptor 623 reviewed G-protein coupled receptor
P48357 BXGT010627 Leptin receptor 3953 reviewed Signaling
P50416 BXGT010797 Carnitine O-palmitoyltransferase 1, liver isoform 1374 reviewed Enzyme
P60880 BXGT011335 Synaptosomal-associated protein 25 6616 reviewed Transporter
P78556 BXGT011849 C-C motif chemokine 20 6364 reviewed Signaling
Q02156 BXGT012639 Protein kinase C epsilon type 5581 reviewed Kinase
Q02928 BXGT012680 Cytochrome P450 4A11 1579 reviewed Enzyme
Q04206 BXGT012754 Transcription factor p65 5970 reviewed Transcription factor
Q04917 BXGT012791 14-3-3 protein eta 7533 reviewed Chaperone
Q05655 BXGT012832 Protein kinase C delta type 5580 reviewed Kinase
Q07812 BXGT012940 Apoptosis regulator BAX 581 reviewed Signaling
Q07817 BXGT012941 Bcl-2-like protein 1 598 reviewed Signaling
Q07869 BXGT012945 Peroxisome proliferator-activated receptor alpha 5465 reviewed Nuclear receptor
Q14654 BXGT013495 ATP-sensitive inward rectifier potassium channel 11 3767 reviewed Ion channel
Q15067 BXGT013532 Peroxisomal acyl-coenzyme A oxidase 1 51 reviewed Enzyme
Q16654 BXGT013650 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial 5166 reviewed Kinase
Q16853 BXGT013683 Membrane primary amine oxidase 8639 reviewed
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q99683 BXGT019947 Mitogen-activated protein kinase kinase kinase 5 4217 reviewed Kinase
P16615 BXGT023653 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 488 reviewed Transporter
P00403 BXGT026137 Cytochrome c oxidase subunit 2 4513 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease