adisease

Showing entry for Alloxan Diabetes

General Disease Information
BXGD Id	BXGD000104
Disease Name	Alloxan Diabetes
Disease CUI Id	C0002152
MeSH Codes	C18 C19
Disease Class Name	Nutritional and Metabolic Diseases; Endocrine System Diseases
Semantic Type	Experimental Model of Disease
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O43524	BXGT004599	Forkhead box protein O3	2309	reviewed
O95831	BXGT005399	Apoptosis-inducing factor 1, mitochondrial	9131	reviewed	Enzyme
P00390	BXGT005526	Glutathione reductase, mitochondrial	2936	reviewed	Enzyme
P00441	BXGT005540	Superoxide dismutase [Cu-Zn]	6647	reviewed	Enzyme
P00797	BXGT005658	Renin	5972	reviewed	Enzyme
P01019	BXGT005717	Angiotensinogen	183	reviewed	Enzyme modulator
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P03886	BXGT006108	NADH-ubiquinone oxidoreductase chain 1	4535	reviewed	Enzyme
P04040	BXGT006132	Catalase	847	reviewed	Enzyme
P04179	BXGT006163	Superoxide dismutase [Mn], mitochondrial	6648	reviewed	Enzyme
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P04798	BXGT006265	Cytochrome P450 1A1	1543	reviewed	Enzyme
P04839	BXGT006273	Cytochrome b-245 heavy chain	1536	reviewed	Ion channel
P05121	BXGT006320	Plasminogen activator inhibitor 1	5054	reviewed	Enzyme modulator
P05164	BXGT006333	Myeloperoxidase	4353	reviewed	Enzyme
P05231	BXGT006345	Interleukin-6	3569	reviewed
P05362	BXGT006350	Intercellular adhesion molecule 1	3383	reviewed
P06213	BXGT006425	Insulin receptor	3643	reviewed	Kinase
P06703	BXGT006477	Protein S100-A6	6277	reviewed	Calcium-binding protein
P07203	BXGT006566	Glutathione peroxidase 1	2876	reviewed	Enzyme
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	1129	reviewed	G-protein coupled receptor
P08253	BXGT006757	72 kDa type IV collagenase	4313	reviewed	Enzyme
P08842	BXGT006830	Steryl-sulfatase	412	reviewed	Enzyme
P09601	BXGT006909	Heme oxygenase 1	3162	reviewed
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P10997	BXGT007643	Islet amyloid polypeptide	3375	reviewed	Signaling
P11168	BXGT007663	Solute carrier family 2, facilitated glucose transporter member 2	6514	reviewed	Transporter
P11474	BXGT007710	Steroid hormone receptor ERR1	2101	reviewed	Nuclear receptor
P11498	BXGT007714	Pyruvate carboxylase, mitochondrial	5091	reviewed	Enzyme
P12821	BXGT007849	Angiotensin-converting enzyme	1636	reviewed	Enzyme
P13945	BXGT007972	Beta-3 adrenergic receptor	155	reviewed	G-protein coupled receptor
P14598	BXGT008024	Neutrophil cytosol factor 1	653361	reviewed
P14672	BXGT008037	Solute carrier family 2, facilitated glucose transporter member 4	6517	reviewed	Transporter
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P15559	BXGT008139	NAD(P)H dehydrogenase [quinone] 1	1728	reviewed
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P17252	BXGT008294	Protein kinase C alpha type	5578	reviewed	Kinase
P18847	BXGT008431	Cyclic AMP-dependent transcription factor ATF-3	467	reviewed	Transcription factor
P19367	BXGT008476	Hexokinase-1	3098	reviewed	Kinase
P19438	BXGT008480	Tumor necrosis factor receptor superfamily member 1A	7132	reviewed
P19634	BXGT008504	Sodium/hydrogen exchanger 1	6548	reviewed	Transporter
P20813	BXGT008603	Cytochrome P450 2B6	1555	reviewed
P20815	BXGT008604	Cytochrome P450 3A5	1577	reviewed	Enzyme
P28845	BXGT009297	Corticosteroid 11-beta-dehydrogenase isozyme 1	3290	reviewed
P29474	BXGT009352	Nitric oxide synthase, endothelial	4846	reviewed
P30613	BXGT009447	Pyruvate kinase PKLR	5313	reviewed	Kinase
P33121	BXGT009692	Long-chain-fatty-acid--CoA ligase 1	2180	reviewed	Enzyme
P35228	BXGT009800	Nitric oxide synthase, inducible	4843	reviewed
P35348	BXGT009814	Alpha-1A adrenergic receptor	148	reviewed	G-protein coupled receptor
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P35557	BXGT009846	Glucokinase	2645	reviewed	Kinase
P35558	BXGT009847	Phosphoenolpyruvate carboxykinase, cytosolic [GTP]	5105	reviewed	Kinase
P36956	BXGT009947	Sterol regulatory element-binding protein 1	6720	reviewed
P37231	BXGT009972	Peroxisome proliferator-activated receptor gamma	5468	reviewed	Nuclear receptor
P42574	BXGT010317	Caspase-3	836	reviewed	Enzyme
P46663	BXGT010531	B1 bradykinin receptor	623	reviewed	G-protein coupled receptor
P48357	BXGT010627	Leptin receptor	3953	reviewed	Signaling
P50416	BXGT010797	Carnitine O-palmitoyltransferase 1, liver isoform	1374	reviewed	Enzyme
P60880	BXGT011335	Synaptosomal-associated protein 25	6616	reviewed	Transporter
P78556	BXGT011849	C-C motif chemokine 20	6364	reviewed	Signaling
Q02156	BXGT012639	Protein kinase C epsilon type	5581	reviewed	Kinase
Q02928	BXGT012680	Cytochrome P450 4A11	1579	reviewed	Enzyme
Q04206	BXGT012754	Transcription factor p65	5970	reviewed	Transcription factor
Q04917	BXGT012791	14-3-3 protein eta	7533	reviewed	Chaperone
Q05655	BXGT012832	Protein kinase C delta type	5580	reviewed	Kinase
Q07812	BXGT012940	Apoptosis regulator BAX	581	reviewed	Signaling
Q07817	BXGT012941	Bcl-2-like protein 1	598	reviewed	Signaling
Q07869	BXGT012945	Peroxisome proliferator-activated receptor alpha	5465	reviewed	Nuclear receptor
Q14654	BXGT013495	ATP-sensitive inward rectifier potassium channel 11	3767	reviewed	Ion channel
Q15067	BXGT013532	Peroxisomal acyl-coenzyme A oxidase 1	51	reviewed	Enzyme
Q16654	BXGT013650	[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial	5166	reviewed	Kinase
Q16853	BXGT013683	Membrane primary amine oxidase	8639	reviewed
Q96EB6	BXGT019646	NAD-dependent protein deacetylase sirtuin-1	23411	reviewed	Epigenetic regulator
Q99683	BXGT019947	Mitogen-activated protein kinase kinase kinase 5	4217	reviewed	Kinase
P16615	BXGT023653	Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	488	reviewed	Transporter
P00403	BXGT026137	Cytochrome c oxidase subunit 2	4513	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}