Showing entry for Carboxypeptidase B


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT008078
Protein NameCarboxypeptidase B
Uniport IdP15086
GeneCPB1
Gene Id1360
DomainPeptidase_M14; Propep_M14
Pfam PF00246   PF02244  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
5. Organismal Systems 5.4 Digestive system hsa04972 Pancreatic secretion
5. Organismal Systems 5.4 Digestive system hsa04974 Protein digestion and absorption
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006508 proteolysis
molecular function GO:0004180 carboxypeptidase activity
molecular function GO:0004181 metallocarboxypeptidase activity
molecular function GO:0008270 zinc ion binding
cellular component GO:0005615 extracellular space
Reactome
Pathway Id Pathway Name
R-HSA-2022377 Metabolism of Angiotensinogen to Angiotensins
R-HSA-2980736 Peptide hormone metabolism
R-HSA-392499 Metabolism of proteins
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001339 BXGD000041 Acute pancreatitis Digestive System Diseases
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0003864 BXGD000231 Arthritis Musculoskeletal Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004238 BXGD000262 Atrial Fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0005779 BXGD000336 Blood Coagulation Disorders Hemic and Lymphatic Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011991 BXGD000766 Diarrhea Pathological Conditions, Signs and Symptoms
C0015302 BXGD000974 External exotoses Musculoskeletal Diseases
C0015672 BXGD001011 Fatigue Pathological Conditions, Signs and Symptoms
C0018798 BXGD001223 Congenital Heart Defects Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0018801 BXGD001226 Heart failure Cardiovascular Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0018818 BXGD001236 Ventricular Septal Defects Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0022660 BXGD001571 Kidney Failure, Acute Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023281 BXGD001628 Leishmaniasis Infections; Skin and Connective Tissue Diseases
C0023283 BXGD001629 Leishmaniasis, Cutaneous Infections; Skin and Connective Tissue Diseases
C0023290 BXGD001631 Leishmaniasis, Visceral Infections
C0023530 BXGD001683 Leukopenia Hemic and Lymphatic Diseases
C0023890 BXGD001713 Liver Cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0024530 BXGD001783 Malaria Infections
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0027497 BXGD001993 Nausea Pathological Conditions, Signs and Symptoms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027947 BXGD002061 Neutropenia Hemic and Lymphatic Diseases
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0034091 BXGD002463 Pulmonary Veno-Occlusive Disease (disorder) Respiratory Tract Diseases; Cardiovascular Diseases
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0039103 BXGD002791 Synovitis Musculoskeletal Diseases
C0040028 BXGD002835 Thrombocythemia, Essential Hemic and Lymphatic Diseases
C0085696 BXGD003244 Chronic prostatitis Male Urogenital Diseases
C0149521 BXGD003328 Pancreatitis, Chronic Digestive System Diseases
C0155626 BXGD003806 Acute myocardial infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0232197 BXGD004536 Fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0264714 BXGD005416 Acute heart failure Cardiovascular Diseases
C0278134 BXGD006498 Absence of sensation Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0333307 BXGD006946 Superficial ulcer Pathological Conditions, Signs and Symptoms
C0578575 BXGD009550 Dissection of proximal aorta
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0876973 BXGD011322 Infectious Lung Disorder Infections; Respiratory Tract Diseases
C1335302 BXGD012775 Pancreatic Ductal Adenocarcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C1623038 BXGD013475 Cirrhosis Pathological Conditions, Signs and Symptoms
C1832661 BXGD013866 ANOPHTHALMIA AND PULMONARY HYPOPLASIA Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Respiratory Tract Diseases
C1853230 BXGD015317 Aphakia, congenital primary Eye Diseases
C1956089 BXGD016615 Osteophyte Musculoskeletal Diseases
C2931038 BXGD017944 Pancreatic carcinoma, familial Digestive System Diseases; Neoplasms; Endocrine System Diseases
C2931788 BXGD018064 Atypical Hemolytic Uremic Syndrome Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Hemic and Lymphatic Diseases
C2985280 BXGD018223 Blood Protein Measurement
C3160909 BXGD018497 Autoimmune arthritis
C3887524 BXGD019892 Skin Erosion Skin and Connective Tissue Diseases
C4721772 BXGD023767 Postoperative delirium Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C4721773 BXGD023768 Postoperative cognitive dysfunction
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0006198 Citric acid 192.12
BXGC0015494 Lysianadioic Acid 215.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein