Showing entry for Blood Coagulation Disorders


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD000336
Disease NameBlood Coagulation Disorders
Disease CUI IdC0005779
MeSH Codes C15  
Disease Class NameHemic and Lymphatic Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id HP:0001871  
Human Phenotype Ontology TermAbnormality of blood and blood-forming tissues
Disease Ontology Id DOID:630   DOID:7  
Disease Ontology Class Namegenetic disease; disease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O15123 BXGT004130 Angiopoietin-2 285 reviewed Signaling
O60674 BXGT004892 Tyrosine-protein kinase JAK2 3717 reviewed Kinase
O60858 BXGT004903 E3 ubiquitin-protein ligase TRIM13 10206 reviewed
O75469 BXGT005128 Nuclear receptor subfamily 1 group I member 2 8856 reviewed Nuclear receptor
O95255 BXGT005363 Multidrug resistance-associated protein 6 368 reviewed Transporter
O95342 BXGT005373 Bile salt export pump 8647 reviewed Transporter
O95477 BXGT005383 Phospholipid-transporting ATPase ABCA1 19 reviewed Transporter
P00451 BXGT005545 Coagulation factor VIII 2157 reviewed Enzyme
P00488 BXGT005552 Coagulation factor XIII A chain 2162 reviewed Enzyme
P00734 BXGT005630 Prothrombin 2147 reviewed Enzyme
P00740 BXGT005634 Coagulation factor IX 2158 reviewed Enzyme
P00742 BXGT005636 Coagulation factor X 2159 reviewed Enzyme
P00747 BXGT005639 Plasminogen 5340 reviewed Enzyme
P00748 BXGT005640 Coagulation factor XII 2161 reviewed Enzyme
P00749 BXGT005641 Urokinase-type plasminogen activator 5328 reviewed Enzyme
P00750 BXGT005642 Tissue-type plasminogen activator 5327 reviewed Enzyme
P00797 BXGT005658 Renin 5972 reviewed Enzyme
P01008 BXGT005713 Antithrombin-III 462 reviewed Enzyme modulator
P01009 BXGT005714 Alpha-1-antitrypsin 5265 reviewed Enzyme modulator
P01011 BXGT005715 Alpha-1-antichymotrypsin 12 reviewed Enzyme modulator
P01023 BXGT005718 Alpha-2-macroglobulin 2 reviewed Enzyme modulator
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P01909 BXGT005815 HLA class II histocompatibility antigen, DQ alpha 1 chain 3117 reviewed Immune response
P01920 BXGT005817 HLA class II histocompatibility antigen, DQ beta 1 chain 3119 reviewed Immune response
P02144 BXGT005853 Myoglobin 4151 reviewed
P02452 BXGT005878 Collagen alpha-1(I) chain 1277 reviewed
P02462 BXGT005881 Collagen alpha-1(IV) chain 1282 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P03951 BXGT006117 Coagulation factor XI 2160 reviewed Enzyme
P03952 BXGT006118 Plasma kallikrein 3818 reviewed Enzyme
P04004 BXGT006125 Vitronectin 7448 reviewed
P04040 BXGT006132 Catalase 847 reviewed Enzyme
P04070 BXGT006143 Vitamin K-dependent protein C 5624 reviewed Enzyme
P04155 BXGT006155 Trefoil factor 1 7031 reviewed Signaling
P04275 BXGT006180 von Willebrand factor 7450 reviewed Enzyme modulator
P05062 BXGT006305 Fructose-bisphosphate aldolase B 229 reviewed
P05106 BXGT006315 Integrin beta-3 3690 reviewed Receptor
P05107 BXGT006316 Integrin beta-2 3689 reviewed Receptor
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P05155 BXGT006328 Plasma protease C1 inhibitor 710 reviewed Enzyme modulator
P05231 BXGT006345 Interleukin-6 3569 reviewed
P06396 BXGT006435 Gelsolin 2934 reviewed Cellular structure
P06733 BXGT006490 Alpha-enolase 2023 reviewed Enzyme
P07204 BXGT006567 Thrombomodulin 7056 reviewed
P07225 BXGT006572 Vitamin K-dependent protein S 5627 reviewed
P07288 BXGT006591 Prostate-specific antigen 354 reviewed Enzyme
P07355 BXGT006609 Annexin A2 302 reviewed
P07359 BXGT006612 Platelet glycoprotein Ib alpha chain 2811 reviewed Receptor
P08311 BXGT006762 Cathepsin G 1511 reviewed Enzyme
P08514 BXGT006781 Integrin alpha-IIb 3674 reviewed
P08572 BXGT006791 Collagen alpha-2(IV) chain 1284 reviewed
P08697 BXGT006815 Alpha-2-antiplasmin 5345 reviewed Enzyme modulator
P08709 BXGT006818 Coagulation factor VII 2155 reviewed Enzyme
P09466 BXGT006892 Glycodelin 5047 reviewed Enzyme
P09601 BXGT006909 Heme oxygenase 1 3162 reviewed
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P10276 BXGT007553 Retinoic acid receptor alpha 5914 reviewed Nuclear receptor
P10644 BXGT007597 cAMP-dependent protein kinase type I-alpha regulatory subunit 5573 reviewed
P10646 BXGT007598 Tissue factor pathway inhibitor 7035 reviewed Enzyme modulator
P11308 BXGT007684 Transcriptional regulator ERG 2078 reviewed Transcription factor
P11498 BXGT007714 Pyruvate carboxylase, mitochondrial 5091 reviewed Enzyme
P12814 BXGT007847 Alpha-actinin-1 87 reviewed
P13501 BXGT007917 C-C motif chemokine 5 6352 reviewed Signaling
P13726 BXGT007950 Tissue factor 2152 reviewed Receptor
P14598 BXGT008024 Neutrophil cytosol factor 1 653361 reviewed
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P15086 BXGT008078 Carboxypeptidase B 1360 reviewed Enzyme
P15289 BXGT008102 Arylsulfatase A 410 reviewed Enzyme
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P16109 BXGT008194 P-selectin 6403 reviewed
P16671 BXGT008255 Platelet glycoprotein 4 948 reviewed Receptor
P17931 BXGT008356 Galectin-3 3958 reviewed Signaling
P18827 BXGT008427 Syndecan-1 6382 reviewed Extracellular structure
P20701 BXGT008591 Integrin alpha-L 3683 reviewed
P21333 BXGT008638 Filamin-A 2316 reviewed
P21709 BXGT008685 Ephrin type-A receptor 1 2041 reviewed Kinase
P21802 BXGT008691 Fibroblast growth factor receptor 2 2263 reviewed Kinase
P21817 BXGT008693 Ryanodine receptor 1 6261 reviewed Ion channel
P22607 BXGT008784 Fibroblast growth factor receptor 3 2261 reviewed Kinase
P22894 BXGT008815 Neutrophil collagenase 4317 reviewed Enzyme
P23219 BXGT008837 Prostaglandin G/H synthase 1 5742 reviewed Enzyme
P24298 BXGT008960 Alanine aminotransferase 1 2875 reviewed Enzyme
P25116 BXGT009025 Proteinase-activated receptor 1 2149 reviewed G-protein coupled receptor
P27708 BXGT009202 CAD protein 790 reviewed Enzyme
P29323 BXGT009334 Ephrin type-B receptor 2 2048 reviewed Kinase
P34949 BXGT009775 Mannose-6-phosphate isomerase 4351 reviewed Enzyme
P35579 BXGT009852 Myosin-9 4627 reviewed
P35968 BXGT009887 Vascular endothelial growth factor receptor 2 3791 reviewed Kinase
P36955 BXGT009946 Pigment epithelium-derived factor 5176 reviewed Enzyme modulator
P37023 BXGT009953 Serine/threonine-protein kinase receptor R3 94 reviewed Kinase
P38435 BXGT010040 Vitamin K-dependent gamma-carboxylase 2677 reviewed
P39060 BXGT010088 Collagen alpha-1(XVIII) chain 80781 reviewed
P40225 BXGT010168 Thrombopoietin 7066 reviewed
P41180 BXGT010230 Extracellular calcium-sensing receptor 846 reviewed G-protein coupled receptor
P41212 BXGT010235 Transcription factor ETV6 2120 reviewed Transcription factor
P41235 BXGT010241 Hepatocyte nuclear factor 4-alpha 3172 reviewed Nuclear receptor
P42224 BXGT010286 Signal transducer and activator of transcription 1-alpha/beta 6772 reviewed Nucleic acid binding
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P43652 BXGT010405 Afamin 173 reviewed Transporter
P47712 BXGT010577 Cytosolic phospholipase A2 5321 reviewed Enzyme
P47900 BXGT010595 P2Y purinoceptor 1 5028 reviewed G-protein coupled receptor
P49257 BXGT010687 Protein ERGIC-53 3998 reviewed Transporter
P51857 BXGT010899 Aldo-keto reductase family 1 member D1 6718 reviewed Enzyme
P55087 BXGT011105 Aquaporin-4 361 reviewed Ion channel
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P62834 BXGT011464 Ras-related protein Rap-1A 5906 reviewed Enzyme modulator
P63261 BXGT011512 Actin, cytoplasmic 2 71 reviewed Cellular structure
P78310 BXGT011830 Coxsackievirus and adenovirus receptor 1525 reviewed
Q00059 BXGT012512 Transcription factor A, mitochondrial 7019 reviewed
Q02083 BXGT012633 N-acylethanolamine-hydrolyzing acid amidase 27163 reviewed Enzyme
Q03164 BXGT012700 Histone-lysine N-methyltransferase 2A 4297 reviewed
Q06124 BXGT012856 Tyrosine-protein phosphatase non-receptor type 11 5781 reviewed
Q06187 BXGT012860 Tyrosine-protein kinase BTK 695 reviewed Kinase
Q12913 BXGT013279 Receptor-type tyrosine-protein phosphatase eta 5795 reviewed Enzyme
Q13485 BXGT013363 Mothers against decapentaplegic homolog 4 4089 reviewed Transcription factor
Q13586 BXGT013380 Stromal interaction molecule 1 6786 reviewed
Q13698 BXGT013392 Voltage-dependent L-type calcium channel subunit alpha-1S 779 reviewed Ion channel
Q13822 BXGT013396 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 5168 reviewed Enzyme
Q13976 BXGT013409 cGMP-dependent protein kinase 1 5592 reviewed Kinase
Q14032 BXGT013438 Bile acid-CoA:amino acid N-acyltransferase 570 reviewed
Q14393 BXGT013466 Growth arrest-specific protein 6 2621 reviewed Extracellular structure
Q14994 BXGT013519 Nuclear receptor subfamily 1 group I member 3 9970 reviewed Nuclear receptor
Q15389 BXGT013564 Angiopoietin-1 284 reviewed Signaling
Q15833 BXGT013605 Syntaxin-binding protein 2 6813 reviewed Transporter
Q16568 BXGT013640 Cocaine- and amphetamine-regulated transcript protein 9607 reviewed
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q5Y7D3 BXGT015912 HLA class II histocompatibility antigen DQ beta chain 3119 unreviewed
Q76LX8 BXGT016870 A disintegrin and metalloproteinase with thrombospondin motifs 13 11093 reviewed Enzyme
Q7KZI7 BXGT016990 Serine/threonine-protein kinase MARK2 2011 reviewed Kinase
Q7L266 BXGT016993 Isoaspartyl peptidase/L-asparaginase 80150 reviewed Enzyme
Q8NI22 BXGT018571 Multiple coagulation factor deficiency protein 2 90411 reviewed Transporter
Q8TDQ0 BXGT018810 Hepatitis A virus cellular receptor 2 84868 reviewed
Q8TDS5 BXGT018813 Oxoeicosanoid receptor 1 165140 reviewed G-protein coupled receptor
Q8TDV0 BXGT018815 Probable G-protein coupled receptor 151 134391 reviewed G-protein coupled receptor
Q92963 BXGT019401 GTP-binding protein Rit1 6016 reviewed Enzyme modulator
Q96IY4 BXGT019678 Carboxypeptidase B2 1361 reviewed Enzyme
Q99700 BXGT019949 Ataxin-2 6311 reviewed Nucleic acid binding
Q9BQB6 BXGT020108 Vitamin K epoxide reductase complex subunit 1 79001 reviewed Enzyme
Q9H244 BXGT020448 P2Y purinoceptor 12 64805 reviewed G-protein coupled receptor
Q9HCN6 BXGT020535 Platelet glycoprotein VI 51206 reviewed Receptor
Q9P2J5 BXGT021301 Leucine--tRNA ligase, cytoplasmic 51520 reviewed
Q9UJ41 BXGT021723 Rab5 GDP/GTP exchange factor 27342 reviewed Enzyme modulator
Q9ULV1 BXGT021764 Frizzled-4 8322 reviewed G-protein coupled receptor
Q9Y251 BXGT022215 Heparanase 10855 reviewed Enzyme
Q9Y619 BXGT022316 Mitochondrial ornithine transporter 1 10166 reviewed Transporter
P16284 BXGT022972 Platelet endothelial cell adhesion molecule 5175 reviewed Cell adhesion
Q01543 BXGT023137 Friend leukemia integration 1 transcription factor 2313 reviewed Transcription factor
P29590 BXGT024350 Protein PML 5371 reviewed
Q9UIJ7 BXGT026029 GTP:AMP phosphotransferase AK3, mitochondrial 50808 reviewed Kinase
P07320 BXGT026150 Gamma-crystallin D 1421 reviewed
P21731 BXGT026174 Thromboxane A2 receptor 6915 reviewed G-protein coupled receptor
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease