Showing entry for Alpha-1D adrenergic receptor



                       
General Target Information
BXGT IdBXGT008930
Protein NameAlpha-1D adrenergic receptor
Uniport IdP23944
GeneAdra1d
Gene Id29413
Domain7tm_1
Pfam PF00001  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway
Biological Process GO:0007568 aging
Biological Process GO:0007267 cell-cell signaling
Biological Process GO:0060073 micturition
Biological Process GO:0001986 negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure
Biological Process GO:0150099 neuron-glial cell signaling
Biological Process GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure
Biological Process GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway
Biological Process GO:0007204 positive regulation of cytosolic calcium ion concentration
Biological Process GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine
Biological Process GO:0043410 positive regulation of MAPK cascade
Biological Process GO:0045907 positive regulation of vasoconstriction
molecular function GO:0004937 alpha1-adrenergic receptor activity
molecular function GO:0004930 G protein-coupled receptor activity
molecular function GO:0042802 identical protein binding
cellular component GO:0005829 cytosol
cellular component GO:0005887 integral component of plasma membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000538 (R)-Norepinephrine 169.18
BXGC0001591 (+)-O-Methylarmepavine 327.42
BXGC0001767 (E)-Resveratrol 228.25
BXGC0003196 Aripiprazole 448.39
BXGC0004763 Octopamine 153.18
BXGC0005611 Coclaurine 285.34
BXGC0005867 Serotonin 176.22
BXGC0005871 Dopamine 153.18
BXGC0014455 Fanchinin 622.3
BXGC0014707 Dehydroevodiamine 302.13
BXGC0017443 Phenylephrine 167.09
BXGC0021210 Phenylpropanolamine 151.1
BXGC0021478 Lipoic Acid 206.04
BXGC0021893 Norepinephrine 169.07
BXGC0024245 4-[(6,7-Dimethoxy-2-Methyl-3,4-Dihydro-1H-Isoquinolin-1-Yl)Methyl]Phenol 313.17
BXGC0024988 Nifedipine 346.12
BXGC0027118 Tamsulosin 408.17
BXGC0031384 Epinephrine 183.09
BXGC0033356 isonotholaenic acid 302.12
BXGC0038892 (1R,2S)-Phenylpropanolamine 151.1
BXGC0042222 Propranolol 259.16
BXGC0042510 Fluoxetine 309.13
BXGC0043126 Nicardipine 479.21
BXGC0045812 Trifluoperazine 407.16
BXGC0046755 Yohimbine 354.19
BXGC0047871 7-Hydroxyflavone 238.06
BXGC0048241 4-[(6,7-Dimethoxy-1,2,3,4-Tetrahydroisoquinolin-1-Yl)Methyl]Phenol 299.15
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein