Showing entry for Presenile dementia


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD000708
Disease NamePresenile dementia
Disease CUI IdC0011265
MeSH Codes C10   F03  
Disease Class NameNervous System Diseases; Mental Disorders
Semantic TypeMental or Behavioral Dysfunction
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
F7VJQ1 BXGT003310 Alternative prion protein 5621 reviewed
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O00264 BXGT003904 Membrane-associated progesterone receptor component 1 10857 reviewed Signaling
O00767 BXGT003949 Acyl-CoA desaturase 6319 reviewed
O14556 BXGT004069 Glyceraldehyde-3-phosphate dehydrogenase, testis-specific 26330 reviewed Enzyme
O14561 BXGT004071 Acyl carrier protein, mitochondrial 4706 reviewed Transporter
O14578 BXGT004072 Citron Rho-interacting kinase 11113 reviewed Kinase
O14618 BXGT004076 Copper chaperone for superoxide dismutase 9973 reviewed Enzyme
O14672 BXGT004081 Disintegrin and metalloproteinase domain-containing protein 10 102 reviewed
O14773 BXGT004096 Tripeptidyl-peptidase 1 1200 reviewed Enzyme
O14920 BXGT004110 Inhibitor of nuclear factor kappa-B kinase subunit beta 3551 reviewed Kinase
O14964 BXGT004116 Hepatocyte growth factor-regulated tyrosine kinase substrate 9146 reviewed
O15151 BXGT004132 Protein Mdm4 4194 reviewed Nucleic acid binding
O15269 BXGT004145 Serine palmitoyltransferase 1 10558 reviewed Enzyme
O43524 BXGT004599 Forkhead box protein O3 2309 reviewed
O43914 BXGT004635 TYRO protein tyrosine kinase-binding protein 7305 reviewed
O60260 BXGT004864 E3 ubiquitin-protein ligase parkin 5071 reviewed Enzyme
O60313 BXGT004871 Dynamin-like 120 kDa protein, mitochondrial 4976 reviewed Enzyme modulator
O60603 BXGT004887 Toll-like receptor 2 7097 reviewed
O75129 BXGT005101 Astrotactin-2 23245 reviewed
O75347 BXGT005113 Tubulin-specific chaperone A 6902 reviewed Chaperone
O75369 BXGT005119 Filamin-B 2317 reviewed
O75469 BXGT005128 Nuclear receptor subfamily 1 group I member 2 8856 reviewed Nuclear receptor
O75489 BXGT005131 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial 4722 reviewed
O75628 BXGT005140 GTP-binding protein REM 1 28954 reviewed
O75716 BXGT005147 Serine/threonine-protein kinase 16 8576 reviewed Kinase
O75874 BXGT005157 Isocitrate dehydrogenase [NADP] cytoplasmic 3417 reviewed
O76054 BXGT005172 SEC14-like protein 2 23541 reviewed
O76083 BXGT005176 High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A 5152 reviewed
O94759 BXGT005327 Transient receptor potential cation channel subfamily M member 2 7226 reviewed Ion channel
O94925 BXGT005342 Glutaminase kidney isoform, mitochondrial 2744 reviewed Enzyme
O95278 BXGT005370 Laforin 7957 reviewed
O95477 BXGT005383 Phospholipid-transporting ATPase ABCA1 19 reviewed Transporter
O95786 BXGT005396 Probable ATP-dependent RNA helicase DDX58 23586 reviewed
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] 6647 reviewed Enzyme
P00450 BXGT005544 Ceruloplasmin 1356 reviewed Enzyme
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P00734 BXGT005630 Prothrombin 2147 reviewed Enzyme
P00749 BXGT005641 Urokinase-type plasminogen activator 5328 reviewed Enzyme
P00797 BXGT005658 Renin 5972 reviewed Enzyme
P00813 BXGT005667 Adenosine deaminase 100 reviewed Enzyme
P01009 BXGT005714 Alpha-1-antitrypsin 5265 reviewed Enzyme modulator
P01011 BXGT005715 Alpha-1-antichymotrypsin 12 reviewed Enzyme modulator
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P01023 BXGT005718 Alpha-2-macroglobulin 2 reviewed Enzyme modulator
P01034 BXGT005721 Cystatin-C 1471 reviewed
P01042 BXGT005722 Kininogen-1 3827 reviewed Enzyme modulator
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01138 BXGT005738 Beta-nerve growth factor 4803 reviewed Signaling
P01215 BXGT005743 Glycoprotein hormones alpha chain 1081 reviewed
P01270 BXGT005746 Parathyroid hormone 5741 reviewed
P01275 BXGT005747 Glucagon 2641 reviewed
P01303 BXGT005748 Pro-neuropeptide Y 4852 reviewed Signaling
P01308 BXGT005749 Insulin 3630 reviewed
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P01730 BXGT005781 T-cell surface glycoprotein CD4 920 reviewed
P02462 BXGT005881 Collagen alpha-1(IV) chain 1282 reviewed
P02545 BXGT005889 Prelamin-A/C 4000 reviewed
P02647 BXGT005908 Apolipoprotein A-I 335 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02654 BXGT005911 Apolipoprotein C-I 341 reviewed
P02656 BXGT005913 Apolipoprotein C-III 345 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02751 BXGT005943 Fibronectin 2335 reviewed Signaling
P02753 BXGT005945 Retinol-binding protein 4 5950 reviewed Transporter
P02766 BXGT005953 Transthyretin 7276 reviewed Transporter
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P02787 BXGT005962 Serotransferrin 7018 reviewed Enzyme
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P04062 BXGT006140 Lysosomal acid glucosylceramidase 2629 reviewed
P04083 BXGT006147 Annexin A1 301 reviewed
P04150 BXGT006154 Glucocorticoid receptor 2908 reviewed Nuclear receptor
P04156 BXGT006156 Major prion protein 5621 reviewed
P04179 BXGT006163 Superoxide dismutase [Mn], mitochondrial 6648 reviewed Enzyme
P04271 BXGT006177 Protein S100-B 6285 reviewed Calcium-binding protein
P04275 BXGT006180 von Willebrand factor 7450 reviewed Enzyme modulator
P04278 BXGT006182 Sex hormone-binding globulin 6462 reviewed
P04406 BXGT006207 Glyceraldehyde-3-phosphate dehydrogenase 2597 reviewed Enzyme
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04818 BXGT006269 Thymidylate synthase 7298 reviewed Enzyme
P05067 BXGT006306 Amyloid-beta precursor protein 351 reviewed Enzyme modulator
P05091 BXGT006312 Aldehyde dehydrogenase, mitochondrial 217 reviewed Enzyme
P05107 BXGT006316 Integrin beta-2 3689 reviewed Receptor
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P05154 BXGT006327 Plasma serine protease inhibitor 5104 reviewed Enzyme modulator
P05155 BXGT006328 Plasma protease C1 inhibitor 710 reviewed Enzyme modulator
P05164 BXGT006333 Myeloperoxidase 4353 reviewed Enzyme
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05362 BXGT006350 Intercellular adhesion molecule 1 3383 reviewed
P05771 BXGT006384 Protein kinase C beta type 5579 reviewed Kinase
P06213 BXGT006425 Insulin receptor 3643 reviewed Kinase
P06276 BXGT006430 Cholinesterase 590 reviewed
P06731 BXGT006488 Carcinoembryonic antigen-related cell adhesion molecule 5 1048 reviewed
P06733 BXGT006490 Alpha-enolase 2023 reviewed Enzyme
P06850 BXGT006511 Corticoliberin 1392 reviewed Signaling
P06858 BXGT006515 Lipoprotein lipase 4023 reviewed Enzyme
P07202 BXGT006565 Thyroid peroxidase 7173 reviewed Enzyme
P07237 BXGT006576 Protein disulfide-isomerase 5034 reviewed
P07333 BXGT006602 Macrophage colony-stimulating factor 1 receptor 1436 reviewed Kinase
P07339 BXGT006604 Cathepsin D 1509 reviewed Enzyme
P07737 BXGT006663 Profilin-1 5216 reviewed
P07858 BXGT006689 Cathepsin B 1508 reviewed Enzyme
P07996 BXGT006710 Thrombospondin-1 7057 reviewed
P08069 BXGT006723 Insulin-like growth factor 1 receptor 3480 reviewed Kinase
P08183 BXGT006741 ATP-dependent translocase ABCB1 5243 reviewed Transporter
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08254 BXGT006758 Stromelysin-1 4314 reviewed Enzyme
P08473 BXGT006773 Neprilysin 4311 reviewed Enzyme
P08572 BXGT006791 Collagen alpha-2(IV) chain 1284 reviewed
P08887 BXGT006835 Interleukin-6 receptor subunit alpha 3570 reviewed Signaling
P09429 BXGT006889 High mobility group protein B1 3146 reviewed Nucleic acid binding
P09466 BXGT006892 Glycodelin 5047 reviewed Enzyme
P09601 BXGT006909 Heme oxygenase 1 3162 reviewed
P09936 BXGT006943 Ubiquitin carboxyl-terminal hydrolase isozyme L1 7345 reviewed Enzyme
P0CG47 BXGT007467 Polyubiquitin-B 7314 reviewed Nucleic acid binding
P0DN79 BXGT007511 Cystathionine beta-synthase-like protein 875 reviewed
P10147 BXGT007543 C-C motif chemokine 3 6348 reviewed Signaling
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10635 BXGT007595 Cytochrome P450 2D6 1565 reviewed
P10636 BXGT007596 Microtubule-associated protein tau 4137 reviewed
P10646 BXGT007598 Tissue factor pathway inhibitor 7035 reviewed Enzyme modulator
P10909 BXGT007630 Clusterin 1191 reviewed
P10997 BXGT007643 Islet amyloid polypeptide 3375 reviewed Signaling
P11137 BXGT007656 Microtubule-associated protein 2 4133 reviewed
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 1128 reviewed G-protein coupled receptor
P11413 BXGT007701 Glucose-6-phosphate 1-dehydrogenase 2539 reviewed Enzyme
P11511 BXGT007717 Aromatase 1588 reviewed Enzyme
P11597 BXGT007727 Cholesteryl ester transfer protein 1071 reviewed
P11717 BXGT007740 Cation-independent mannose-6-phosphate receptor 3482 reviewed Receptor
P12081 BXGT007772 Histidine--tRNA ligase, cytoplasmic 3035 reviewed Enzyme
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P13236 BXGT007891 C-C motif chemokine 4 6351 reviewed
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P14210 BXGT007994 Hepatocyte growth factor 3082 reviewed Enzyme
P14416 BXGT008011 D(2) dopamine receptor 1813 reviewed G-protein coupled receptor
P14616 BXGT008026 Insulin receptor-related protein 3645 reviewed Kinase
P14672 BXGT008037 Solute carrier family 2, facilitated glucose transporter member 4 6517 reviewed Transporter
P14735 BXGT008042 Insulin-degrading enzyme 3416 reviewed Enzyme
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P15121 BXGT008083 Aldo-keto reductase family 1 member B1 231 reviewed Enzyme
P15289 BXGT008102 Arylsulfatase A 410 reviewed Enzyme
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P16109 BXGT008194 P-selectin 6403 reviewed
P16220 BXGT008206 Cyclic AMP-responsive element-binding protein 1 1385 reviewed
P16581 BXGT008245 E-selectin 6401 reviewed
P17405 BXGT008304 Sphingomyelin phosphodiesterase 6609 reviewed Enzyme
P17516 BXGT008313 Aldo-keto reductase family 1 member C4 1109 reviewed Enzyme
P17643 BXGT008323 5,6-dihydroxyindole-2-carboxylic acid oxidase 7306 reviewed Enzyme
P17676 BXGT008327 CCAAT/enhancer-binding protein beta 1051 reviewed Transcription factor
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 1141 reviewed Ion channel
P17936 BXGT008357 Insulin-like growth factor-binding protein 3 3486 reviewed Enzyme modulator
P17948 BXGT008358 Vascular endothelial growth factor receptor 1 2321 reviewed Kinase
P19320 BXGT008470 Vascular cell adhesion protein 1 7412 reviewed
P19429 BXGT008479 Troponin I, cardiac muscle 7137 reviewed Cellular structure
P20132 BXGT008546 L-serine dehydratase/L-threonine deaminase 10993 reviewed Enzyme
P21359 BXGT008640 Neurofibromin 4763 reviewed Enzyme modulator
P21397 BXGT008644 Amine oxidase [flavin-containing] A 4128 reviewed
P21554 BXGT008662 Cannabinoid receptor 1 1268 reviewed G-protein coupled receptor
P21709 BXGT008685 Ephrin type-A receptor 1 2041 reviewed Kinase
P21964 BXGT008714 Catechol O-methyltransferase 1312 reviewed Enzyme
P22303 BXGT008751 Acetylcholinesterase 43 reviewed Enzyme
P23193 BXGT008834 Transcription elongation factor A protein 1 6917 reviewed Nucleic acid binding
P23416 BXGT008865 Glycine receptor subunit alpha-2 2742 reviewed Ion channel
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P25440 BXGT009044 Bromodomain-containing protein 2 6046 reviewed Epigenetic regulator
P25705 BXGT009060 ATP synthase subunit alpha, mitochondrial 498 reviewed Transporter
P26358 BXGT009104 DNA (cytosine-5)-methyltransferase 1 1786 reviewed Epigenetic regulator
P27169 BXGT009161 Serum paraoxonase/arylesterase 1 5444 reviewed
P27338 BXGT009172 Amine oxidase [flavin-containing] B 4129 reviewed
P27352 BXGT009174 Cobalamin binding intrinsic factor 2694 reviewed
P27361 BXGT009176 Mitogen-activated protein kinase 3 5595 reviewed Kinase
P27487 BXGT009187 Dipeptidyl peptidase 4 1803 reviewed Enzyme
P28223 BXGT009239 5-hydroxytryptamine receptor 2A 3356 reviewed G-protein coupled receptor
P28329 BXGT009251 Choline O-acetyltransferase 1103 reviewed Enzyme
P28676 BXGT009284 Grancalcin 25801 reviewed
P28845 BXGT009297 Corticosteroid 11-beta-dehydrogenase isozyme 1 3290 reviewed
P28907 BXGT009301 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 952 reviewed Enzyme
P29460 BXGT009348 Interleukin-12 subunit beta 3593 reviewed Signaling
P29466 BXGT009349 Caspase-1 834 reviewed Enzyme
P29474 BXGT009352 Nitric oxide synthase, endothelial 4846 reviewed
P29475 BXGT009353 Nitric oxide synthase, brain 4842 reviewed
P30044 BXGT009395 Peroxiredoxin-5, mitochondrial 25824 reviewed
P30086 BXGT009400 Phosphatidylethanolamine-binding protein 1 5037 reviewed Enzyme modulator
P30533 BXGT009434 Alpha-2-macroglobulin receptor-associated protein 4043 reviewed
P30536 BXGT009435 Translocator protein 706 reviewed
P30556 BXGT009441 Type-1 angiotensin II receptor 185 reviewed G-protein coupled receptor
P30566 BXGT009446 Adenylosuccinate lyase 158 reviewed Enzyme
P31639 BXGT009556 Sodium/glucose cotransporter 2 6524 reviewed Transporter
P31645 BXGT009558 Sodium-dependent serotonin transporter 6532 reviewed Transporter
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P34913 BXGT009770 Bifunctional epoxide hydrolase 2 2053 reviewed Enzyme
P34947 BXGT009774 G protein-coupled receptor kinase 5 2869 reviewed Kinase
P35228 BXGT009800 Nitric oxide synthase, inducible 4843 reviewed
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35462 BXGT009835 D(3) dopamine receptor 1814 reviewed G-protein coupled receptor
P35520 BXGT009842 Cystathionine beta-synthase 875 reviewed
P35658 BXGT009859 Nuclear pore complex protein Nup214 8021 reviewed Nucleic acid binding
P35858 BXGT009876 Insulin-like growth factor-binding protein complex acid labile subunit 3483 reviewed Receptor
P35869 BXGT009877 Aryl hydrocarbon receptor 196 reviewed Transcription factor
P36222 BXGT009914 Chitinase-3-like protein 1 1116 reviewed
P36544 BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 89832 reviewed
P36956 BXGT009947 Sterol regulatory element-binding protein 1 6720 reviewed
P36969 BXGT009949 Phospholipid hydroperoxide glutathione peroxidase 2879 reviewed Enzyme
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P37840 BXGT010015 Alpha-synuclein 6622 reviewed Transporter
P38398 BXGT010037 Breast cancer type 1 susceptibility protein 672 reviewed Enzyme
P38936 BXGT010074 Cyclin-dependent kinase inhibitor 1 1026 reviewed
P40933 BXGT010209 Interleukin-15 3600 reviewed
P42224 BXGT010286 Signal transducer and activator of transcription 1-alpha/beta 6772 reviewed Nucleic acid binding
P42345 BXGT010304 Serine/threonine-protein kinase mTOR 2475 reviewed Kinase
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P42575 BXGT010318 Caspase-2 835 reviewed Enzyme
P42658 BXGT010327 Dipeptidyl aminopeptidase-like protein 6 1804 reviewed Enzyme
P42858 BXGT010341 Huntingtin 3064 reviewed
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P43004 BXGT010348 Excitatory amino acid transporter 2 6506 reviewed Transporter
P43220 BXGT010367 Glucagon-like peptide 1 receptor 2740 reviewed G-protein coupled receptor
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 1137 reviewed Ion channel
P48061 BXGT010616 Stromal cell-derived factor 1 6387 reviewed
P48506 BXGT010635 Glutamate--cysteine ligase catalytic subunit 2729 reviewed Enzyme
P48735 BXGT010657 Isocitrate dehydrogenase [NADP], mitochondrial 3418 reviewed
P49763 BXGT010737 Placenta growth factor 5228 reviewed Signaling
P49768 BXGT010740 Presenilin-1 5663 reviewed Enzyme
P49810 BXGT010747 Presenilin-2 5664 reviewed Enzyme
P49841 BXGT010750 Glycogen synthase kinase-3 beta 2932 reviewed Kinase
P50052 BXGT010768 Type-2 angiotensin II receptor 186 reviewed G-protein coupled receptor
P50406 BXGT010796 5-hydroxytryptamine receptor 6 3362 reviewed G-protein coupled receptor
P51681 BXGT010878 C-C chemokine receptor type 5 1234 reviewed G-protein coupled receptor
P52758 BXGT010951 2-iminobutanoate/2-iminopropanoate deaminase 10247 reviewed
P53667 BXGT011008 LIM domain kinase 1 3984 reviewed Kinase
P54802 BXGT011081 Alpha-N-acetylglucosaminidase 4669 reviewed
P55055 BXGT011101 Oxysterols receptor LXR-beta 7376 reviewed Nuclear receptor
P55072 BXGT011103 Transitional endoplasmic reticulum ATPase 7415 reviewed
P55085 BXGT011104 Proteinase-activated receptor 2 2150 reviewed G-protein coupled receptor
P56817 BXGT011200 Beta-secretase 1 23621 reviewed Enzyme
P60174 BXGT011294 Triosephosphate isomerase 7167 reviewed Enzyme
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P60880 BXGT011335 Synaptosomal-associated protein 25 6616 reviewed Transporter
P61073 BXGT011352 C-X-C chemokine receptor type 4 7852 reviewed G-protein coupled receptor
P62258 BXGT011415 14-3-3 protein epsilon 7531 reviewed Chaperone
P63261 BXGT011512 Actin, cytoplasmic 2 71 reviewed Cellular structure
P78330 BXGT011833 Phosphoserine phosphatase 5723 reviewed Enzyme
P78344 BXGT011835 Eukaryotic translation initiation factor 4 gamma 2 1982 reviewed Nucleic acid binding
P78352 BXGT011836 Disks large homolog 4 1742 reviewed Receptor
P78504 BXGT011844 Protein jagged-1 182 reviewed
P81172 BXGT011935 Hepcidin 57817 reviewed
P98155 BXGT012226 Very low-density lipoprotein receptor 7436 reviewed
P98160 BXGT012228 Basement membrane-specific heparan sulfate proteoglycan core protein 3339 reviewed Enzyme modulator
P98164 BXGT012230 Low-density lipoprotein receptor-related protein 2 4036 reviewed
Q00059 BXGT012512 Transcription factor A, mitochondrial 7019 reviewed
Q00613 BXGT012540 Heat shock factor protein 1 3297 reviewed Transcription factor
Q00796 BXGT012549 Sorbitol dehydrogenase 6652 reviewed Enzyme
Q00987 BXGT012559 E3 ubiquitin-protein ligase Mdm2 4193 reviewed Nucleic acid binding
Q01094 BXGT012568 Transcription factor E2F1 1869 reviewed Nucleic acid binding
Q01105 BXGT012569 Protein SET 6418 reviewed Enzyme modulator
Q01959 BXGT012624 Sodium-dependent dopamine transporter 6531 reviewed Transporter
Q03154 BXGT012698 Aminoacylase-1 95 reviewed
Q04609 BXGT012768 Glutamate carboxypeptidase 2 2346 reviewed Enzyme
Q04637 BXGT012771 Eukaryotic translation initiation factor 4 gamma 1 1981 reviewed Nucleic acid binding
Q05397 BXGT012815 Focal adhesion kinase 1 5747 reviewed Kinase
Q06787 BXGT012890 Synaptic functional regulator FMR1 2332 reviewed Nucleic acid binding
Q07812 BXGT012940 Apoptosis regulator BAX 581 reviewed Signaling
Q07869 BXGT012945 Peroxisome proliferator-activated receptor alpha 5465 reviewed Nuclear receptor
Q08209 BXGT012968 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform 5530 reviewed
Q13093 BXGT013310 Platelet-activating factor acetylhydrolase 7941 reviewed Enzyme
Q13148 BXGT013318 TAR DNA-binding protein 43 23435 reviewed
Q13224 BXGT013328 Glutamate receptor ionotropic, NMDA 2B 2904 reviewed Ion channel
Q13231 BXGT013329 Chitotriosidase-1 1118 reviewed
Q13315 BXGT013339 Serine-protein kinase ATM 472 reviewed Kinase
Q13393 BXGT013346 Phospholipase D1 5337 reviewed
Q13501 BXGT013365 Sequestosome-1 8878 reviewed
Q13526 BXGT013369 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 5300 reviewed
Q13535 BXGT013370 Serine/threonine-protein kinase ATR 545 reviewed Kinase
Q13627 BXGT013385 Dual specificity tyrosine-phosphorylation-regulated kinase 1A 1859 reviewed Kinase
Q14002 BXGT013433 Carcinoembryonic antigen-related cell adhesion molecule 7 1087 reviewed
Q14114 BXGT013441 Low-density lipoprotein receptor-related protein 8 7804 reviewed
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q14118 BXGT013444 Dystroglycan 1605 reviewed Receptor
Q14203 BXGT013455 Dynactin subunit 1 1639 reviewed Chaperone
Q14624 BXGT013491 Inter-alpha-trypsin inhibitor heavy chain H4 3700 reviewed Enzyme modulator
Q15109 BXGT013537 Advanced glycosylation end product-specific receptor 177 reviewed Receptor
Q15125 BXGT013543 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 10682 reviewed Enzyme
Q15389 BXGT013564 Angiopoietin-1 284 reviewed Signaling
Q15392 BXGT013566 Delta(24)-sterol reductase 1718 reviewed Enzyme
Q15746 BXGT013591 Myosin light chain kinase, smooth muscle 4638 reviewed Kinase
Q15848 BXGT013609 Adiponectin 9370 reviewed
Q16548 BXGT013636 Bcl-2-related protein A1 597 reviewed Signaling
Q16555 BXGT013638 Dihydropyrimidinase-related protein 2 1808 reviewed Enzyme
Q16620 BXGT013645 BDNF/NT-3 growth factors receptor 4915 reviewed Kinase
Q16739 BXGT013663 Ceramide glucosyltransferase 7357 reviewed Enzyme
Q16769 BXGT013665 Glutaminyl-peptide cyclotransferase 25797 reviewed Enzyme
Q30154 BXGT014296 HLA class II histocompatibility antigen, DR beta 5 chain 3127 reviewed Immune response
Q30201 BXGT014297 Hereditary hemochromatosis protein 3077 reviewed
Q5S007 BXGT015650 Leucine-rich repeat serine/threonine-protein kinase 2 120892 reviewed Kinase
Q6N021 BXGT016378 Methylcytosine dioxygenase TET2 54790 reviewed
Q76LX8 BXGT016870 A disintegrin and metalloproteinase with thrombospondin motifs 13 11093 reviewed Enzyme
Q8IXJ6 BXGT018362 NAD-dependent protein deacetylase sirtuin-2 22933 reviewed Epigenetic regulator
Q8NBP7 BXGT018541 Proprotein convertase subtilisin/kexin type 9 255738 reviewed Enzyme
Q8NFD2 BXGT018559 Ankyrin repeat and protein kinase domain-containing protein 1 255239 reviewed Kinase
Q8TDS5 BXGT018813 Oxoeicosanoid receptor 1 165140 reviewed G-protein coupled receptor
Q8TDV0 BXGT018815 Probable G-protein coupled receptor 151 134391 reviewed G-protein coupled receptor
Q92542 BXGT019354 Nicastrin 23385 reviewed
Q92692 BXGT019361 Nectin-2 5819 reviewed
Q92731 BXGT019366 Estrogen receptor beta 2100 reviewed Nuclear receptor
Q92769 BXGT019370 Histone deacetylase 2 3066 reviewed Epigenetic regulator
Q92835 BXGT019382 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 3635 reviewed
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q96G91 BXGT019663 P2Y purinoceptor 11 5032 reviewed G-protein coupled receptor
Q96GD0 BXGT019665 Pyridoxal phosphate phosphatase 57026 reviewed Enzyme
Q96QV1 BXGT019722 Hedgehog-interacting protein 64399 reviewed
Q99497 BXGT019926 Protein/nucleic acid deglycase DJ-1 11315 reviewed Enzyme
Q99574 BXGT019936 Neuroserpin 5274 reviewed Enzyme modulator
Q99700 BXGT019949 Ataxin-2 6311 reviewed Nucleic acid binding
Q99707 BXGT019952 Methionine synthase 4548 reviewed
Q99720 BXGT019955 Sigma non-opioid intracellular receptor 1 10280 reviewed
Q99784 BXGT019961 Noelin 10439 reviewed Cellular structure
Q9BV57 BXGT020140 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 55256 reviewed Enzyme
Q9BXM7 BXGT020172 Serine/threonine-protein kinase PINK1, mitochondrial 65018 reviewed Kinase
Q9BYF1 BXGT020186 Angiotensin-converting enzyme 2 59272 reviewed Enzyme
Q9C0B1 BXGT020209 Alpha-ketoglutarate-dependent dioxygenase FTO 79068 reviewed
Q9GZX6 BXGT020428 Interleukin-22 50616 reviewed
Q9H3M7 BXGT020462 Thioredoxin-interacting protein 10628 reviewed
Q9H4A3 BXGT020473 Serine/threonine-protein kinase WNK1 65125 reviewed Kinase
Q9H9B1 BXGT020501 Histone-lysine N-methyltransferase EHMT1 79813 reviewed Epigenetic regulator
Q9HCB6 BXGT020529 Spondin-1 10418 reviewed Extracellular structure
Q9NP58 BXGT021143 ATP-binding cassette sub-family B member 6, mitochondrial 10058 reviewed Transporter
Q9NPH5 BXGT021159 NADPH oxidase 4 50507 reviewed Enzyme
Q9NR71 BXGT021180 Neutral ceramidase 56624 reviewed
Q9NRF2 BXGT021185 SH2B adapter protein 1 25970 reviewed
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9P2R7 BXGT021304 Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial 8803 reviewed Enzyme
Q9UHD2 BXGT021697 Serine/threonine-protein kinase TBK1 29110 reviewed Kinase
Q9UHI8 BXGT021701 A disintegrin and metalloproteinase with thrombospondin motifs 1 9510 reviewed Enzyme
Q9UKV5 BXGT021751 E3 ubiquitin-protein ligase AMFR 267 reviewed
Q9UL54 BXGT021755 Serine/threonine-protein kinase TAO2 9344 reviewed Kinase
Q9ULV1 BXGT021764 Frizzled-4 8322 reviewed G-protein coupled receptor
Q9UM07 BXGT021771 Protein-arginine deiminase type-4 23569 reviewed
Q9UM47 BXGT021772 Neurogenic locus notch homolog protein 3 4854 reviewed
Q9UM73 BXGT021773 ALK tyrosine kinase receptor 238 reviewed Kinase
Q9UQF0 BXGT021812 Syncytin-1 30816 reviewed
Q9Y2W7 BXGT022250 Calsenilin 30818 reviewed Ion channel
Q9Y5W5 BXGT022303 Wnt inhibitory factor 1 11197 reviewed Calcium-binding protein
Q9Y5X9 BXGT022307 Endothelial lipase 9388 reviewed Enzyme
Q9Y5Z0 BXGT022310 Beta-secretase 2 25825 reviewed Enzyme
Q9Y6A2 BXGT022324 Cholesterol 24-hydroxylase 10858 reviewed Enzyme
P00738 BXGT022874 Haptoglobin 3240 reviewed Enzyme
P09622 BXGT023116 Dihydrolipoyl dehydrogenase, mitochondrial 1738 reviewed Enzyme
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
Q9UBP0 BXGT023601 Spastin 6683 reviewed Cellular structure
P35670 BXGT023695 Copper-transporting ATPase 2 540 reviewed Transporter
P40198 BXGT023750 Carcinoembryonic antigen-related cell adhesion molecule 3 1084 reviewed
P20138 BXGT023857 Myeloid cell surface antigen CD33 945 reviewed Receptor
Q8IX03 BXGT024000 Protein KIBRA 23286 reviewed
P51608 BXGT025073 Methyl-CpG-binding protein 2 4204 reviewed Epigenetic regulator
Q96MS0 BXGT025241 Roundabout homolog 3 64221 reviewed Receptor
Q86SQ9 BXGT025875 Dehydrodolichyl diphosphate synthase complex subunit DHDDS 79947 reviewed Enzyme
P61916 BXGT025881 NPC intracellular cholesterol transporter 2 10577 reviewed
P00403 BXGT026137 Cytochrome c oxidase subunit 2 4513 reviewed Enzyme
P07320 BXGT026150 Gamma-crystallin D 1421 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease