adisease

Showing entry for Hyponatremia

General Disease Information
BXGD Id	BXGD001451
Disease Name	Hyponatremia
Disease CUI Id	C0020625
MeSH Codes	C18
Disease Class Name	Nutritional and Metabolic Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0001939
Human Phenotype Ontology Term	Abnormality of metabolism/homeostasis
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O14733	BXGT004087	Dual specificity mitogen-activated protein kinase kinase 7	5609	reviewed	Kinase
O15409	BXGT004166	Forkhead box protein P2	93986	reviewed
O43570	BXGT004601	Carbonic anhydrase 12	771	reviewed
O43612	BXGT004605	Orexin	3060	reviewed
O60931	BXGT004911	Cystinosin	1497	reviewed
O95551	BXGT005384	Tyrosyl-DNA phosphodiesterase 2	51567	reviewed
O95970	BXGT005409	Leucine-rich glioma-inactivated protein 1	9211	reviewed
P00797	BXGT005658	Renin	5972	reviewed	Enzyme
P01019	BXGT005717	Angiotensinogen	183	reviewed	Enzyme modulator
P01189	BXGT005742	Pro-opiomelanocortin	5443	reviewed
P01579	BXGT005770	Interferon gamma	3458	reviewed
P02671	BXGT005914	Fibrinogen alpha chain	2243	reviewed
P02741	BXGT005936	C-reactive protein	1401	reviewed
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P03372	BXGT006059	Estrogen receptor	2099	reviewed	Nuclear receptor
P04818	BXGT006269	Thymidylate synthase	7298	reviewed	Enzyme
P05108	BXGT006317	Cholesterol side-chain cleavage enzyme, mitochondrial	1583	reviewed
P05231	BXGT006345	Interleukin-6	3569	reviewed
P07900	BXGT006696	Heat shock protein HSP 90-alpha	3320	reviewed	Chaperone
P08183	BXGT006741	ATP-dependent translocase ABCB1	5243	reviewed	Transporter
P08235	BXGT006751	Mineralocorticoid receptor	4306	reviewed	Nuclear receptor
P08397	BXGT006768	Porphobilinogen deaminase	3145	reviewed	Enzyme
P10635	BXGT007595	Cytochrome P450 2D6	1565	reviewed
P11166	BXGT007661	Solute carrier family 2, facilitated glucose transporter member 1	6513	reviewed	Transporter
P12821	BXGT007849	Angiotensin-converting enzyme	1636	reviewed	Enzyme
P13569	BXGT007923	Cystic fibrosis transmembrane conductance regulator	1080	reviewed	Ion channel
P15056	BXGT008075	Serine/threonine-protein kinase B-raf	673	reviewed	Kinase
P15538	BXGT008137	Cytochrome P450 11B1, mitochondrial	1584	reviewed
P18074	BXGT008374	General transcription and DNA repair factor IIH helicase subunit XPD	2068	reviewed	Enzyme
P19099	BXGT008456	Cytochrome P450 11B2, mitochondrial	1585	reviewed
P21817	BXGT008693	Ryanodine receptor 1	6261	reviewed	Ion channel
P21964	BXGT008714	Catechol O-methyltransferase	1312	reviewed	Enzyme
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P23975	BXGT008935	Sodium-dependent noradrenaline transporter	6530	reviewed	Transporter
P24298	BXGT008960	Alanine aminotransferase 1	2875	reviewed	Enzyme
P30518	BXGT009428	Vasopressin V2 receptor	554	reviewed	G-protein coupled receptor
P30556	BXGT009441	Type-1 angiotensin II receptor	185	reviewed	G-protein coupled receptor
P35499	BXGT009839	Sodium channel protein type 4 subunit alpha	6329	reviewed	Ion channel
P35658	BXGT009859	Nuclear pore complex protein Nup214	8021	reviewed	Nucleic acid binding
P36551	BXGT009927	Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial	1371	reviewed	Enzyme
P37088	BXGT009961	Amiloride-sensitive sodium channel subunit alpha	6337	reviewed	Ion channel
P48048	BXGT010610	ATP-sensitive inward rectifier potassium channel 1	3758	reviewed	Ion channel
P51168	BXGT010842	Amiloride-sensitive sodium channel subunit beta	6338	reviewed	Ion channel
P51170	BXGT010843	Amiloride-sensitive sodium channel subunit gamma	6340	reviewed	Ion channel
P51449	BXGT010846	Nuclear receptor ROR-gamma	6097	reviewed	Nuclear receptor
P51800	BXGT010892	Chloride channel protein ClC-Ka	1187	reviewed	Ion channel
P51843	BXGT010897	Nuclear receptor subfamily 0 group B member 1	190	reviewed	Nuclear receptor
P55087	BXGT011105	Aquaporin-4	361	reviewed	Ion channel
P80365	BXGT011895	Corticosteroid 11-beta-dehydrogenase isozyme 2	3291	reviewed	Enzyme
Q00653	BXGT012541	Nuclear factor NF-kappa-B p100 subunit	4791	reviewed	Transcription factor
Q01718	BXGT012609	Adrenocorticotropic hormone receptor	4158	reviewed	G-protein coupled receptor
Q01959	BXGT012624	Sodium-dependent dopamine transporter	6531	reviewed	Transporter
Q01968	BXGT012626	Inositol polyphosphate 5-phosphatase OCRL-1	4952	reviewed	Enzyme
Q13315	BXGT013339	Serine-protein kinase ATM	472	reviewed	Kinase
Q13423	BXGT013352	NAD(P) transhydrogenase, mitochondrial	23530	reviewed	Enzyme
Q8NCC3	BXGT018546	Group XV phospholipase A2	23659	reviewed	Enzyme
Q9HBA0	BXGT020516	Transient receptor potential cation channel subfamily V member 4	59341	reviewed	Ion channel
Q9NNW7	BXGT021139	Thioredoxin reductase 2, mitochondrial	10587	reviewed	Enzyme
Q9NR19	BXGT021175	Acetyl-coenzyme A synthetase, cytoplasmic	55902	reviewed	Enzyme
Q9UGM3	BXGT025543	Deleted in malignant brain tumors 1 protein	1755	reviewed	Enzyme
O43613	BXGT025666	Orexin receptor type 1	3061	reviewed	G-protein coupled receptor

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}