Showing entry for Glutaredoxin-1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT009863
Protein NameGlutaredoxin-1
Uniport IdP35754
GeneGLRX
Gene Id2745
DomainGlutaredoxin
Pfam PF00462  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0045454 cell redox homeostasis
Biological Process GO:0015949 nucleobase-containing small molecule interconversion
Biological Process GO:0045838 positive regulation of membrane potential
Biological Process GO:2000651 positive regulation of sodium ion transmembrane transporter activity
Biological Process GO:0080058 protein deglutathionylation
molecular function GO:0009055 electron transfer activity
molecular function GO:0015038 glutathione disulfide oxidoreductase activity
molecular function GO:0097573 glutathione oxidoreductase activity
molecular function GO:0047485 protein N-terminus binding
cellular component GO:0005829 cytosol
cellular component GO:0070062 extracellular exosome
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-15869 Metabolism of nucleotides
R-HSA-499943 Interconversion of nucleotide di- and triphosphates
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002793 BXGD000130 Anaplasia Pathological Conditions, Signs and Symptoms; Neoplasms
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0004623 BXGD000282 Bacterial Infections Infections
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0007787 BXGD000487 Transient Ischemic Attack Nervous System Diseases; Cardiovascular Diseases
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011853 BXGD000752 Diabetes Mellitus, Experimental Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011876 BXGD000758 Cataract due to diabetes mellitus Eye Diseases
C0013537 BXGD000853 Eclampsia Female Urogenital Diseases and Pregnancy Complications
C0015625 BXGD001006 Fanconi Anemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
C0015695 BXGD001013 Fatty Liver Digestive System Diseases
C0015934 BXGD001026 Fetal Growth Retardation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0018784 BXGD001220 Sensorineural Hearing Loss (disorder) Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0021400 BXGD001504 Influenza Infections; Respiratory Tract Diseases
C0023473 BXGD001661 Myeloid Leukemia, Chronic Neoplasms; Hemic and Lymphatic Diseases
C0024115 BXGD001732 Lung diseases Respiratory Tract Diseases
C0024117 BXGD001734 Chronic Obstructive Airway Disease Respiratory Tract Diseases
C0027055 BXGD001964 Myocardial Reperfusion Injury Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027430 BXGD001988 Nasal Polyps Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0028259 BXGD002073 Nodule
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0034069 BXGD002458 Pulmonary Fibrosis Respiratory Tract Diseases
C0035220 BXGD002512 Respiratory Distress Syndrome, Newborn Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases
C0035243 BXGD002522 Respiratory Tract Infections Infections; Respiratory Tract Diseases
C0036202 BXGD002581 Sarcoidosis Hemic and Lymphatic Diseases
C0085084 BXGD003121 Motor Neuron Disease Nervous System Diseases
C0152013 BXGD003516 Adenocarcinoma of lung (disorder) Neoplasms
C0206062 BXGD004148 Lung Diseases, Interstitial Respiratory Tract Diseases
C0206695 BXGD004246 Carcinoma, Neuroendocrine Neoplasms
C0221106 BXGD004390 Alkalemia
C0242339 BXGD005150 Dyslipidemias Nutritional and Metabolic Diseases
C0400966 BXGD008266 Non-alcoholic Fatty Liver Disease Digestive System Diseases
C0410702 BXGD008447 Adolescent idiopathic scoliosis Musculoskeletal Diseases
C0424295 BXGD008524 Hyperactive behavior Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0432283 BXGD008764 Osteoglophonic dwarfism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0520459 BXGD009084 Necrotizing Enterocolitis Digestive System Diseases
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C1142126 BXGD011731 Meningococcal bacteraemia
C1290884 BXGD012198 Inflammatory disorder Pathological Conditions, Signs and Symptoms
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1519670 BXGD013241 Tumor Angiogenesis Pathological Conditions, Signs and Symptoms
C1561643 BXGD013363 Chronic Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1608408 BXGD013434 Malignant transformation
C1800706 BXGD013755 Idiopathic Pulmonary Fibrosis Respiratory Tract Diseases
C1837461 BXGD014234 SCOLIOSIS, ISOLATED, SUSCEPTIBILITY TO, 3
C1853238 BXGD015320 Conotruncal defect
C2363741 BXGD017100 HIV-1 infection
C2711227 BXGD017478 Steatohepatitis Digestive System Diseases
C2945695 BXGD018187 Limb ischemia
C3469521 BXGD018910 FANCONI ANEMIA, COMPLEMENTATION GROUP A (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
C3811653 BXGD019662 Experimental Organism Basal Cell Carcinoma Neoplasms
C4082937 BXGD022095 Necrotizing enterocolitis in fetus OR newborn Digestive System Diseases
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4529962 BXGD023178 Fatty Liver Disease
C4721806 BXGD023772 Carcinoma, Basal Cell Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000989 Glutathione 307.32
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein