adisease

Showing entry for Eclampsia

General Disease Information
BXGD Id	BXGD000853
Disease Name	Eclampsia
Disease CUI Id	C0013537
MeSH Codes	C13
Disease Class Name	Female Urogenital Diseases and Pregnancy Complications
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0001197
Human Phenotype Ontology Term	Abnormality of prenatal development or birth
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O14788	BXGT004100	Tumor necrosis factor ligand superfamily member 11	8600	reviewed	Signaling
O60603	BXGT004887	Toll-like receptor 2	7097	reviewed
O75116	BXGT005100	Rho-associated protein kinase 2	9475	reviewed	Kinase
O75369	BXGT005119	Filamin-B	2317	reviewed
O76054	BXGT005172	SEC14-like protein 2	23541	reviewed
O95477	BXGT005383	Phospholipid-transporting ATPase ABCA1	19	reviewed	Transporter
P00734	BXGT005630	Prothrombin	2147	reviewed	Enzyme
P00742	BXGT005636	Coagulation factor X	2159	reviewed	Enzyme
P00797	BXGT005658	Renin	5972	reviewed	Enzyme
P01019	BXGT005717	Angiotensinogen	183	reviewed	Enzyme modulator
P01100	BXGT005727	Proto-oncogene c-Fos	2353	reviewed	Transcription factor
P01133	BXGT005736	Pro-epidermal growth factor	1950	reviewed
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01308	BXGT005749	Insulin	3630	reviewed
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01589	BXGT005773	Interleukin-2 receptor subunit alpha	3559	reviewed	Receptor
P01889	BXGT005809	HLA class I histocompatibility antigen, B-7 alpha chain	3106	reviewed
P01909	BXGT005815	HLA class II histocompatibility antigen, DQ alpha 1 chain	3117	reviewed	Immune response
P02545	BXGT005889	Prelamin-A/C	4000	reviewed
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P02741	BXGT005936	C-reactive protein	1401	reviewed
P02753	BXGT005945	Retinol-binding protein 4	5950	reviewed	Transporter
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P03372	BXGT006059	Estrogen receptor	2099	reviewed	Nuclear receptor
P04271	BXGT006177	Protein S100-B	6285	reviewed	Calcium-binding protein
P04440	BXGT006216	HLA class II histocompatibility antigen, DP beta 1 chain	3115	reviewed	Immune response
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P05121	BXGT006320	Plasminogen activator inhibitor 1	5054	reviewed	Enzyme modulator
P05156	BXGT006329	Complement factor I	3426	reviewed
P05231	BXGT006345	Interleukin-6	3569	reviewed
P05412	BXGT006354	Transcription factor AP-1	3725	reviewed	Transcription factor
P05771	BXGT006384	Protein kinase C beta type	5579	reviewed	Kinase
P06213	BXGT006425	Insulin receptor	3643	reviewed	Kinase
P06858	BXGT006515	Lipoprotein lipase	4023	reviewed	Enzyme
P07099	BXGT006546	Epoxide hydrolase 1	2052	reviewed
P07204	BXGT006567	Thrombomodulin	7056	reviewed
P07225	BXGT006572	Vitamin K-dependent protein S	5627	reviewed
P07333	BXGT006602	Macrophage colony-stimulating factor 1 receptor	1436	reviewed	Kinase
P07355	BXGT006609	Annexin A2	302	reviewed
P08235	BXGT006751	Mineralocorticoid receptor	4306	reviewed	Nuclear receptor
P08253	BXGT006757	72 kDa type IV collagenase	4313	reviewed	Enzyme
P08476	BXGT006774	Inhibin beta A chain	3624	reviewed	Signaling
P08603	BXGT006798	Complement factor H	3075	reviewed
P08758	BXGT006821	Annexin A5	308	reviewed
P08833	BXGT006827	Insulin-like growth factor-binding protein 1	3484	reviewed	Enzyme modulator
P09488	BXGT006899	Glutathione S-transferase Mu 1	2944	reviewed
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P10599	BXGT007583	Thioredoxin	7295	reviewed
P10635	BXGT007595	Cytochrome P450 2D6	1565	reviewed
P11166	BXGT007661	Solute carrier family 2, facilitated glucose transporter member 1	6513	reviewed	Transporter
P11226	BXGT007675	Mannose-binding protein C	4153	reviewed	Receptor
P11712	BXGT007738	Cytochrome P450 2C9	1559	reviewed
P11766	BXGT007745	Alcohol dehydrogenase class-3	128	reviewed	Enzyme
P12821	BXGT007849	Angiotensin-converting enzyme	1636	reviewed	Enzyme
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P14902	BXGT008065	Indoleamine 2,3-dioxygenase 1	3620	reviewed
P15090	BXGT008079	Fatty acid-binding protein, adipocyte	2167	reviewed
P15529	BXGT008134	Membrane cofactor protein	4179	reviewed
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P16442	BXGT008227	Histo-blood group ABO system transferase	28	reviewed	Enzyme
P17706	BXGT008330	Tyrosine-protein phosphatase non-receptor type 2	5771	reviewed
P17948	BXGT008358	Vascular endothelial growth factor receptor 1	2321	reviewed	Kinase
P19099	BXGT008456	Cytochrome P450 11B2, mitochondrial	1585	reviewed
P19883	BXGT008528	Follistatin	10468	reviewed	Enzyme modulator
P21579	BXGT008665	Synaptotagmin-1	6857	reviewed	Transporter
P21964	BXGT008714	Catechol O-methyltransferase	1312	reviewed	Enzyme
P22455	BXGT008772	Fibroblast growth factor receptor 4	2264	reviewed	Kinase
P23219	BXGT008837	Prostaglandin G/H synthase 1	5742	reviewed	Enzyme
P23945	BXGT008931	Follicle-stimulating hormone receptor	2492	reviewed	G-protein coupled receptor
P24298	BXGT008960	Alanine aminotransferase 1	2875	reviewed	Enzyme
P24593	BXGT008979	Insulin-like growth factor-binding protein 5	3488	reviewed	Enzyme modulator
P25116	BXGT009025	Proteinase-activated receptor 1	2149	reviewed	G-protein coupled receptor
P25440	BXGT009044	Bromodomain-containing protein 2	6046	reviewed	Epigenetic regulator
P27037	BXGT009153	Activin receptor type-2A	92	reviewed	Kinase
P27797	BXGT009206	Calreticulin	811	reviewed	Calcium-binding protein
P29275	BXGT009328	Adenosine receptor A2b	136	reviewed	G-protein coupled receptor
P29474	BXGT009352	Nitric oxide synthase, endothelial	4846	reviewed
P30556	BXGT009441	Type-1 angiotensin II receptor	185	reviewed	G-protein coupled receptor
P34932	BXGT009772	Heat shock 70 kDa protein 4	3308	reviewed
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P35754	BXGT009863	Glutaredoxin-1	2745	reviewed
P35968	BXGT009887	Vascular endothelial growth factor receptor 2	3791	reviewed	Kinase
P37231	BXGT009972	Peroxisome proliferator-activated receptor gamma	5468	reviewed	Nuclear receptor
P37288	BXGT009977	Vasopressin V1a receptor	552	reviewed	G-protein coupled receptor
P37840	BXGT010015	Alpha-synuclein	6622	reviewed	Transporter
P40933	BXGT010209	Interleukin-15	3600	reviewed
P42224	BXGT010286	Signal transducer and activator of transcription 1-alpha/beta	6772	reviewed	Nucleic acid binding
P42898	BXGT010344	Methylenetetrahydrofolate reductase	4524	reviewed
P43652	BXGT010405	Afamin	173	reviewed	Transporter
P46531	BXGT010526	Neurogenic locus notch homolog protein 1	4851	reviewed
P48023	BXGT010604	Tumor necrosis factor ligand superfamily member 6	356	reviewed	Signaling
P48061	BXGT010616	Stromal cell-derived factor 1	6387	reviewed
P49763	BXGT010737	Placenta growth factor	5228	reviewed	Signaling
P55040	BXGT011099	GTP-binding protein GEM	2669	reviewed
P55087	BXGT011105	Aquaporin-4	361	reviewed	Ion channel
P60568	BXGT011315	Interleukin-2	3558	reviewed
P60709	BXGT011322	Actin, cytoplasmic 1	60	reviewed	Cellular structure
P80365	BXGT011895	Corticosteroid 11-beta-dehydrogenase isozyme 2	3291	reviewed	Enzyme
P98170	BXGT012231	E3 ubiquitin-protein ligase XIAP	331	reviewed	Enzyme modulator
Q00796	BXGT012549	Sorbitol dehydrogenase	6652	reviewed	Enzyme
Q03518	BXGT012723	Antigen peptide transporter 1	6890	reviewed	Transporter
Q04206	BXGT012754	Transcription factor p65	5970	reviewed	Transcription factor
Q04721	BXGT012777	Neurogenic locus notch homolog protein 2	4853	reviewed
Q05655	BXGT012832	Protein kinase C delta type	5580	reviewed	Kinase
Q12918	BXGT013280	Killer cell lectin-like receptor subfamily B member 1	3820	reviewed
Q13219	BXGT013327	Pappalysin-1	5069	reviewed
Q13418	BXGT013351	Integrin-linked protein kinase	3611	reviewed	Kinase
Q13478	BXGT013362	Interleukin-18 receptor 1	8809	reviewed	Receptor
Q13618	BXGT013382	Cullin-3	8452	reviewed
Q14116	BXGT013442	Interleukin-18	3606	reviewed
Q14872	BXGT013511	Metal regulatory transcription factor 1	4520	reviewed	Transcription factor
Q15116	BXGT013539	Programmed cell death protein 1	5133	reviewed
Q15389	BXGT013564	Angiopoietin-1	284	reviewed	Signaling
Q15848	BXGT013609	Adiponectin	9370	reviewed
Q16665	BXGT013653	Hypoxia-inducible factor 1-alpha	3091	reviewed	Transcription factor
Q16698	BXGT013659	2,4-dienoyl-CoA reductase, mitochondrial	1666	reviewed	Enzyme
Q5VWK5	BXGT015891	Interleukin-23 receptor	149233	reviewed	Signaling
Q86V24	BXGT017615	Adiponectin receptor protein 2	79602	reviewed	Receptor
Q96AZ6	BXGT019621	Interferon-stimulated gene 20 kDa protein	3669	reviewed
Q9BZS1	BXGT020203	Forkhead box protein P3	50943	reviewed
Q9H4A3	BXGT020473	Serine/threonine-protein kinase WNK1	65125	reviewed	Kinase
Q9UHF0	BXGT021699	Tachykinin-3	6866	reviewed
Q9UQF0	BXGT021812	Syncytin-1	30816	reviewed
P04439	BXGT022649	HLA class I histocompatibility antigen, A-3 alpha chain	3105	reviewed
O75912	BXGT022670	Diacylglycerol kinase iota	9162	reviewed	Enzyme
Q9UM82	BXGT023181	Spermatogenesis-associated protein 2	9825	reviewed
P17535	BXGT023437	Transcription factor jun-D	3727	reviewed	Transcription factor
P53539	BXGT023438	Protein fosB	2354	reviewed	Transcription factor
P00395	BXGT023596	Cytochrome c oxidase subunit 1	4512	reviewed	Enzyme
P15260	BXGT023924	Interferon gamma receptor 1	3459	reviewed	Receptor
Q9BQQ3	BXGT024065	Golgi reassembly-stacking protein 1	64689	reviewed
Q9Y6M1	BXGT025468	Insulin-like growth factor 2 mRNA-binding protein 2	10644	reviewed	Enzyme
Q969H8	BXGT025606	Myeloid-derived growth factor	56005	reviewed
P00403	BXGT026137	Cytochrome c oxidase subunit 2	4513	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}