Showing entry for Soluble calcium-activated nucleotidase 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT018996
Protein NameSoluble calcium-activated nucleotidase 1
Uniport IdQ8WVQ1
GeneCANT1
Gene Id124583
DomainApyrase
Pfam -  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.4 Nucleotide metabolism hsa00230 Purine metabolism
1. Metabolism 1.4 Nucleotide metabolism hsa00240 Pyrimidine metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0043312 neutrophil degranulation
Biological Process GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
Biological Process GO:0030166 proteoglycan biosynthetic process
molecular function GO:0043262 adenosine-diphosphatase activity
molecular function GO:0005509 calcium ion binding
molecular function GO:0004382 guanosine-diphosphatase activity
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0045134 uridine-diphosphatase activity
cellular component GO:0005789 endoplasmic reticulum membrane
cellular component GO:0070062 extracellular exosome
cellular component GO:0005576 extracellular region
cellular component GO:1904813 ficolin-1-rich granule lumen
cellular component GO:0032580 Golgi cisterna membrane
cellular component GO:0016021 integral component of membrane
cellular component GO:0016020 membrane
cellular component GO:0005886 plasma membrane
cellular component GO:0035580 specific granule lumen
cellular component GO:1904724 tertiary granule lumen
Reactome
Pathway Id Pathway Name
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-6798695 Neutrophil degranulation
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000772 BXGD000009 Multiple congenital anomalies Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0004135 BXGD000257 Ataxia Telangiectasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Immune System Diseases; Nervous System Diseases; Cardiovascular Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0008925 BXGD000575 Cleft Palate Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C0009081 BXGD000581 Congenital clubfoot Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0013336 BXGD000815 Dwarfism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C0015300 BXGD000973 Exophthalmos Eye Diseases
C0015672 BXGD001011 Fatigue Pathological Conditions, Signs and Symptoms
C0016202 BXGD001050 Flatfoot Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0017601 BXGD001125 Glaucoma Eye Diseases
C0018564 BXGD001204 Hand deformities Musculoskeletal Diseases
C0018818 BXGD001236 Ventricular Septal Defects Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0020302 BXGD001373 Hydrophthalmos Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0020305 BXGD001374 Hydrops Fetalis Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Immune System Diseases; Hemic and Lymphatic Diseases
C0020678 BXGD001463 Hypotrichosis Skin and Connective Tissue Diseases
C0022821 BXGD001590 Kyphosis deformity of spine Musculoskeletal Diseases
C0024003 BXGD001726 Lordosis Musculoskeletal Diseases
C0025995 BXGD001885 Micromelia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0026034 BXGD001887 Microstomia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0026760 BXGD001927 Multiple Epiphyseal Dysplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0026827 BXGD001936 Muscle hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0027092 BXGD001971 Myopia Eye Diseases
C0027765 BXGD002033 nervous system disorder Nervous System Diseases
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0029456 BXGD002157 Osteoporosis Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0036439 BXGD002615 Scoliosis, unspecified Musculoskeletal Diseases
C0038015 BXGD002726 Spondyloepiphyseal Dysplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0040053 BXGD002839 Thrombosis Cardiovascular Diseases
C0086437 BXGD003282 Joint laxity Musculoskeletal Diseases
C0087012 BXGD003318 Ataxia, Spinocerebellar Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0152235 BXGD003567 Congenital genu recurvatum Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0158486 BXGD003888 Acquired genu recurvatum Musculoskeletal Diseases
C0158761 BXGD003905 Radioulnar Synostosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0220633 BXGD004303 Uveal melanoma Neoplasms; Eye Diseases
C0221357 BXGD004449 Brachydactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0231712 BXGD004519 Waddling gait Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0239137 BXGD004965 Coxa valga Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0239138 BXGD004966 Hip joint varus deformity - observation Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0239479 BXGD004982 Round face
C0241136 BXGD005079 Pain of skin Pathological Conditions, Signs and Symptoms
C0270921 BXGD006133 Axonal neuropathy Nervous System Diseases
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0343284 BXGD007613 Chondrodysplasia Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0392476 BXGD008046 Epiphyseal dysplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0409348 BXGD008384 Flexion contracture of proximal interphalangeal joint
C0426790 BXGD008577 Narrow thorax
C0432242 BXGD008752 Desbuquois syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C0520947 BXGD009126 Clumsiness - motor delay Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0521525 BXGD009139 Short neck
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0542514 BXGD009277 Blue sclera Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0544755 BXGD009310 Genu varum Musculoskeletal Diseases
C0545053 BXGD009323 Advanced bone age
C0546964 BXGD009348 Genu recurvatum
C0575802 BXGD009521 Small hand
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0751651 BXGD010539 Mitochondrial Diseases Nutritional and Metabolic Diseases
C0878659 BXGD011380 Disproportionate short stature Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1836184 BXGD014088 Short femoral neck
C1836542 BXGD014129 Depressed nasal bridge
C1837218 BXGD014207 Cleft palate, isolated Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C1837485 BXGD014239 Flat acetabular roof
C1839546 BXGD014385 Microretrognathia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C1840069 BXGD014433 Sandal gap
C1840077 BXGD014434 Anteverted nostril
C1844704 BXGD014665 Platyspondyly
C1844887 BXGD014690 Catel Manzke syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C1846803 BXGD014840 Small epiphyses
C1849016 BXGD014995 Broad femoral neck
C1849020 BXGD014996 Short metatarsal
C1849039 BXGD014999 Metaphyseal widening
C1849292 BXGD015029 Advanced ossification of carpal bones
C1849293 BXGD015030 Advanced tarsal ossification
C1849311 BXGD015034 Short 1st metacarpal
C1849937 BXGD015091 Disproportionate short-limb short stature
C1850049 BXGD015101 Clinodactyly of the 5th finger
C1853242 BXGD015322 Midface retrusion
C1853761 BXGD015359 SPINOCEREBELLAR ATAXIA, AUTOSOMAL RECESSIVE 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C1854114 BXGD015383 Short nose
C1854301 BXGD015391 Motor delay Mental Disorders
C1855899 BXGD015558 Broad first metatarsal
C1857486 BXGD015710 Low-set, posteriorly rotated ears
C1857527 BXGD015714 Flattened epiphysis
C1858085 BXGD015770 Malar flattening
C1858120 BXGD015774 Generalized hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1860162 BXGD015960 Bifid distal phalanx of the thumb
C1861403 BXGD016045 Variable expressivity
C1865186 BXGD016296 Bell-shaped thorax
C2673394 BXGD017196 Radioulnar dislocation
C2673395 BXGD017197 Proximal fibular overgrowth
C2673396 BXGD017198 Phalangeal dislocation Musculoskeletal Diseases; Wounds and Injuries
C2673401 BXGD017199 Medial deviation of the foot Musculoskeletal Diseases
C2675111 BXGD017272 Abnormal eyelash morphology
C2745959 BXGD017570 Spondyloepiphyseal dysplasia, congenita Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C2981140 BXGD018209 Glaucoma of childhood Eye Diseases
C2981150 BXGD018211 Uranostaphyloschisis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Respiratory Tract Diseases; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C2985280 BXGD018223 Blood Protein Measurement
C3150077 BXGD018291 Mild short stature
C3279757 BXGD018778 CHONDRODYSPLASIA WITH JOINT DISLOCATIONS, GPAPP TYPE
C3553764 BXGD019187 Joint hyperflexibility
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C4012146 BXGD020119 DESBUQUOIS DYSPLASIA 1 Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C4021337 BXGD020612 Partial duplication of the distal phalanx of the hallux
C4023909 BXGD021272 Aplasia/Hypoplasia of the abdominal wall musculature
C4025814 BXGD021806 Abnormality of the metaphysis
C4540251 BXGD023247 EPIPHYSEAL DYSPLASIA, MULTIPLE, 7
C4707307 BXGD023714 Spinocerebellar ataxia with axonal neuropathy type 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002586 Calcium 40.08
BXGC0049447 acetate 59.01
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein