adisease

Showing entry for Thrombosis

General Disease Information
BXGD Id	BXGD002839
Disease Name	Thrombosis
Disease CUI Id	C0040053
MeSH Codes	C14
Disease Class Name	Cardiovascular Diseases
Semantic Type	Pathologic Function
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O43557	BXGT004600	Tumor necrosis factor ligand superfamily member 14	8740	reviewed	Signaling
O60674	BXGT004892	Tyrosine-protein kinase JAK2	3717	reviewed	Kinase
P00451	BXGT005545	Coagulation factor VIII	2157	reviewed	Enzyme
P00488	BXGT005552	Coagulation factor XIII A chain	2162	reviewed	Enzyme
P00734	BXGT005630	Prothrombin	2147	reviewed	Enzyme
P00740	BXGT005634	Coagulation factor IX	2158	reviewed	Enzyme
P00742	BXGT005636	Coagulation factor X	2159	reviewed	Enzyme
P00749	BXGT005641	Urokinase-type plasminogen activator	5328	reviewed	Enzyme
P00750	BXGT005642	Tissue-type plasminogen activator	5327	reviewed	Enzyme
P01008	BXGT005713	Antithrombin-III	462	reviewed	Enzyme modulator
P01019	BXGT005717	Angiotensinogen	183	reviewed	Enzyme modulator
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P02671	BXGT005914	Fibrinogen alpha chain	2243	reviewed
P02675	BXGT005916	Fibrinogen beta chain	2244	reviewed	Signaling
P02679	BXGT005918	Fibrinogen gamma chain	2266	reviewed	Signaling
P02741	BXGT005936	C-reactive protein	1401	reviewed
P02749	BXGT005941	Beta-2-glycoprotein 1	350	reviewed
P03951	BXGT006117	Coagulation factor XI	2160	reviewed	Enzyme
P03952	BXGT006118	Plasma kallikrein	3818	reviewed	Enzyme
P04070	BXGT006143	Vitamin K-dependent protein C	5624	reviewed	Enzyme
P04275	BXGT006180	von Willebrand factor	7450	reviewed	Enzyme modulator
P05106	BXGT006315	Integrin beta-3	3690	reviewed	Receptor
P05121	BXGT006320	Plasminogen activator inhibitor 1	5054	reviewed	Enzyme modulator
P05231	BXGT006345	Interleukin-6	3569	reviewed
P06729	BXGT006486	T-cell surface antigen CD2	914	reviewed
P07204	BXGT006567	Thrombomodulin	7056	reviewed
P07225	BXGT006572	Vitamin K-dependent protein S	5627	reviewed
P07359	BXGT006612	Platelet glycoprotein Ib alpha chain	2811	reviewed	Receptor
P08174	BXGT006739	Complement decay-accelerating factor	1604	reviewed
P08514	BXGT006781	Integrin alpha-IIb	3674	reviewed
P08758	BXGT006821	Annexin A5	308	reviewed
P09601	BXGT006909	Heme oxygenase 1	3162	reviewed
P0C0L4	BXGT007387	Complement C4-A	721	reviewed
P0C0L5	BXGT007388	Complement C4-B	721	reviewed
P10646	BXGT007598	Tissue factor pathway inhibitor	7035	reviewed	Enzyme modulator
P12318	BXGT007799	Low affinity immunoglobulin gamma Fc region receptor II-a	2212	reviewed	Cell adhesion
P13726	BXGT007950	Tissue factor	2152	reviewed	Receptor
P14210	BXGT007994	Hepatocyte growth factor	3082	reviewed	Enzyme
P16109	BXGT008194	P-selectin	6403	reviewed
P17301	BXGT008299	Integrin alpha-2	3673	reviewed
P18146	BXGT008384	Early growth response protein 1	1958	reviewed	Nucleic acid binding
P20815	BXGT008604	Cytochrome P450 3A5	1577	reviewed	Enzyme
P21730	BXGT008687	C5a anaphylatoxin chemotactic receptor 1	728	reviewed	G-protein coupled receptor
P22083	BXGT008727	Alpha-(1,3)-fucosyltransferase 4	2526	reviewed	Enzyme
P23219	BXGT008837	Prostaglandin G/H synthase 1	5742	reviewed	Enzyme
P24557	BXGT008976	Thromboxane-A synthase	6916	reviewed
P29474	BXGT009352	Nitric oxide synthase, endothelial	4846	reviewed
P29965	BXGT009388	CD40 ligand	959	reviewed	Signaling
P30411	BXGT009424	B2 bradykinin receptor	624	reviewed	G-protein coupled receptor
P33261	BXGT009707	Cytochrome P450 2C19	1557	reviewed
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P36888	BXGT009938	Receptor-type tyrosine-protein kinase FLT3	2322	reviewed	Kinase
P40337	BXGT010174	von Hippel-Lindau disease tumor suppressor	7428	reviewed	Enzyme
P41440	BXGT010261	Folate transporter 1	6573	reviewed	Transporter
P42338	BXGT010303	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	5291	reviewed	Kinase
P42898	BXGT010344	Methylenetetrahydrofolate reductase	4524	reviewed
P43115	BXGT010356	Prostaglandin E2 receptor EP3 subtype	5733	reviewed	G-protein coupled receptor
P47900	BXGT010595	P2Y purinoceptor 1	5028	reviewed	G-protein coupled receptor
P48357	BXGT010627	Leptin receptor	3953	reviewed	Signaling
P51575	BXGT010861	P2X purinoceptor 1	5023	reviewed	Ion channel
Q02108	BXGT012634	Guanylate cyclase soluble subunit alpha-1	2982	reviewed
Q06418	BXGT012875	Tyrosine-protein kinase receptor TYRO3	7301	reviewed	Kinase
Q07021	BXGT012915	Complement component 1 Q subcomponent-binding protein, mitochondrial	708	reviewed
Q12866	BXGT013273	Tyrosine-protein kinase Mer	10461	reviewed	Kinase
Q14393	BXGT013466	Growth arrest-specific protein 6	2621	reviewed	Extracellular structure
Q14432	BXGT013469	cGMP-inhibited 3',5'-cyclic phosphodiesterase A	5139	reviewed
Q76LX8	BXGT016870	A disintegrin and metalloproteinase with thrombospondin motifs 13	11093	reviewed	Enzyme
Q8WVQ1	BXGT018996	Soluble calcium-activated nucleotidase 1	124583	reviewed
Q96EB6	BXGT019646	NAD-dependent protein deacetylase sirtuin-1	23411	reviewed	Epigenetic regulator
Q96IY4	BXGT019678	Carboxypeptidase B2	1361	reviewed	Enzyme
Q9BQB6	BXGT020108	Vitamin K epoxide reductase complex subunit 1	79001	reviewed	Enzyme
Q9BYF1	BXGT020186	Angiotensin-converting enzyme 2	59272	reviewed	Enzyme
Q9H244	BXGT020448	P2Y purinoceptor 12	64805	reviewed	G-protein coupled receptor
Q9H4B7	BXGT020475	Tubulin beta-1 chain	81027	reviewed	Cellular structure
Q9HCN6	BXGT020535	Platelet glycoprotein VI	51206	reviewed	Receptor
Q9UNN8	BXGT021791	Endothelial protein C receptor	10544	reviewed	Enzyme modulator
P16284	BXGT022972	Platelet endothelial cell adhesion molecule	5175	reviewed	Cell adhesion
P21731	BXGT026174	Thromboxane A2 receptor	6915	reviewed	G-protein coupled receptor

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}