Showing entry for Metastasis-associated protein MTA1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT023103
Protein NameMetastasis-associated protein MTA1
Uniport IdQ13330
GeneMTA1
Gene Id9112
DomainBAH; ELM2; GATA; MTA_R1; Myb_DNA-binding
Pfam PF01426   PF01448   PF00320   PF17226   PF00249  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0032922 circadian regulation of gene expression
Biological Process GO:0006302 double-strand break repair
Biological Process GO:0043153 entrainment of circadian clock by photoperiod
Biological Process GO:0016575 histone deacetylation
Biological Process GO:0045475 locomotor rhythm
Biological Process GO:0000122 negative regulation of transcription by RNA polymerase II
Biological Process GO:1902499 positive regulation of protein autoubiquitination
Biological Process GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
Biological Process GO:0040029 regulation of gene expression, epigenetic
Biological Process GO:0010212 response to ionizing radiation
Biological Process GO:0007165 signal transduction
molecular function GO:0003682 chromatin binding
molecular function GO:0042826 histone deacetylase binding
molecular function GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
molecular function GO:0001103 RNA polymerase II repressing transcription factor binding
molecular function GO:0003713 transcription coactivator activity
molecular function GO:0003714 transcription corepressor activity
molecular function GO:0008270 zinc ion binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0043231 intracellular membrane-bounded organelle
cellular component GO:0005874 microtubule
cellular component GO:0005635 nuclear envelope
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
cellular component GO:0016581 NuRD complex
Reactome
Pathway Id Pathway Name
R-HSA-1257604 PIP3 activates AKT signaling
R-HSA-1257604 PIP3 activates AKT signaling
R-HSA-162582 Signal Transduction
R-HSA-162582 Signal Transduction
R-HSA-1643685 Disease
R-HSA-212165 Epigenetic regulation of gene expression
R-HSA-2990846 SUMOylation
R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins
R-HSA-3214815 HDACs deacetylate histones
R-HSA-3232118 SUMOylation of transcription factors
R-HSA-3247509 Chromatin modifying enzymes
R-HSA-392499 Metabolism of proteins
R-HSA-427389 ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
R-HSA-4839726 Chromatin organization
R-HSA-5250913 Positive epigenetic regulation of rRNA expression
R-HSA-5663205 Infectious disease
R-HSA-597592 Post-translational protein modification
R-HSA-6807070 PTEN Regulation
R-HSA-6807070 PTEN Regulation
R-HSA-73762 RNA Polymerase I Transcription Initiation
R-HSA-73854 RNA Polymerase I Promoter Clearance
R-HSA-73864 RNA Polymerase I Transcription
R-HSA-74160 Gene expression (Transcription)
R-HSA-74160 Gene expression (Transcription)
R-HSA-8943724 Regulation of PTEN gene transcription
R-HSA-8943724 Regulation of PTEN gene transcription
R-HSA-9006925 Intracellular signaling by second messengers
R-HSA-9006925 Intracellular signaling by second messengers
R-HSA-9679191 Potential therapeutics for SARS
R-HSA-9679506 SARS-CoV Infections
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0003615 BXGD000212 Appendicitis Digestive System Diseases; Infections
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007095 BXGD000423 Carcinoid Tumor Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007103 BXGD000426 Malignant neoplasm of endometrium Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0007124 BXGD000437 Noninfiltrating Intraductal Carcinoma Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0007847 BXGD000492 Malignant tumor of cervix Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0014175 BXGD000904 Endometriosis Female Urogenital Diseases and Pregnancy Complications
C0014859 BXGD000961 Esophageal Neoplasms Digestive System Diseases; Neoplasms
C0015967 BXGD001030 Fever Pathological Conditions, Signs and Symptoms
C0017154 BXGD001097 Gastritis, Atrophic Digestive System Diseases
C0019163 BXGD001295 Hepatitis B Digestive System Diseases; Infections
C0023903 BXGD001720 Liver neoplasms Digestive System Diseases; Neoplasms
C0024232 BXGD001751 Lymphatic Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0024299 BXGD001758 Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0025149 BXGD001826 Medulloblastoma Neoplasms
C0025202 BXGD001832 melanoma Neoplasms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0030421 BXGD002218 Paraganglioma Neoplasms
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0036323 BXGD002595 Schistosomiasis Infections
C0038356 BXGD002747 Stomach Neoplasms Digestive System Diseases; Neoplasms
C0040100 BXGD002840 Thymoma Neoplasms; Hemic and Lymphatic Diseases
C0042341 BXGD002975 Varicocele Male Urogenital Diseases; Cardiovascular Diseases
C0079731 BXGD003087 B-Cell Lymphomas Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0079744 BXGD003090 Diffuse Large B-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0152013 BXGD003516 Adenocarcinoma of lung (disorder) Neoplasms
C0152018 BXGD003518 Esophageal carcinoma Digestive System Diseases; Neoplasms
C0153676 BXGD003679 Secondary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0153690 BXGD003684 Secondary malignant neoplasm of bone Pathological Conditions, Signs and Symptoms; Neoplasms; Musculoskeletal Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0206698 BXGD004248 Cholangiocarcinoma Neoplasms
C0206754 BXGD004289 Neuroendocrine Tumors Neoplasms
C0220668 BXGD004317 Congenital contractural arachnodactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0238198 BXGD004893 Gastrointestinal Stromal Tumors Digestive System Diseases; Neoplasms
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0269102 BXGD006053 Endometrioma Female Urogenital Diseases and Pregnancy Complications
C0272138 BXGD006308 Erythroblastosis
C0278504 BXGD006523 Non-small cell lung cancer stage I
C0278510 BXGD006526 Childhood Medulloblastoma Neoplasms
C0278876 BXGD006607 Adult Medulloblastoma Neoplasms
C0279626 BXGD006657 Squamous cell carcinoma of esophagus Digestive System Diseases; Neoplasms
C0279651 BXGD006674 Gallbladder adenocarcinoma Digestive System Diseases; Neoplasms
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0280100 BXGD006713 Solid Neoplasm Neoplasms
C0280324 BXGD006740 Laryngeal Squamous Cell Carcinoma Neoplasms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0282612 BXGD006820 Prostatic Intraepithelial Neoplasias Neoplasms
C0302592 BXGD006851 Cervix carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0334299 BXGD007027 Carcinoid tumor no ICD-O subtype Neoplasms
C0342637 BXGD007517 Hypocalciuric hypercalcemia, familial, type 1 Nutritional and Metabolic Diseases
C0343641 BXGD007636 Human papilloma virus infection Infections
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0374997 BXGD007967 Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0392514 BXGD008051 Hereditary hemochromatosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0476089 BXGD008977 Endometrial Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0494165 BXGD009022 Secondary malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0546837 BXGD009343 Malignant neoplasm of esophagus Digestive System Diseases; Neoplasms
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0598766 BXGD009669 Leukemogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0677886 BXGD009734 Epithelial ovarian cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0740391 BXGD009987 Middle Cerebral Artery Occlusion Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0812413 BXGD010847 Malignant Pleural Mesothelioma Neoplasms; Respiratory Tract Diseases
C0858252 BXGD011172 Breast adenocarcinoma Neoplasms; Skin and Connective Tissue Diseases
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0936223 BXGD011477 Metastatic Prostate Carcinoma Neoplasms; Male Urogenital Diseases
C1134719 BXGD011688 Invasive Ductal Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1282496 BXGD012147 Metastasis from malignant tumor of prostate
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1332206 BXGD012504 Adult Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332979 BXGD012571 Childhood Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C1336905 BXGD012873 Endometrial Endometrioid Adenocarcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1368683 BXGD012900 Epithelioma Neoplasms
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1512409 BXGD013188 Hepatocarcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C1519670 BXGD013241 Tumor Angiogenesis Pathological Conditions, Signs and Symptoms
C1569637 BXGD013424 Adenocarcinoma, Endometrioid Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1608408 BXGD013434 Malignant transformation
C1853926 BXGD015365 NONAKA MYOPATHY Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2931822 BXGD018068 Nasopharyngeal carcinoma Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C3539878 BXGD019087 Triple Negative Breast Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C3669246 BXGD019326 Mammary adenocarcinoma
C4024988 BXGD021514 Intestinal carcinoid Digestive System Diseases; Neoplasms
C4048328 BXGD021903 cervical cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C4524268 BXGD023104 Advanced lung cancer
C4526607 BXGD023143 Stage I Thymoma AJCC v8
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4721806 BXGD023772 Carcinoma, Basal Cell Neoplasms
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
C4722518 BXGD023806 Triple-Negative Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C4724262 BXGD023812 stage I thymoma
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000140 Phytic acid 660.04
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein