adisease

Showing entry for Paraganglioma

General Disease Information
BXGD Id	BXGD002218
Disease Name	Paraganglioma
Disease CUI Id	C0030421
MeSH Codes	C04
Disease Class Name	Neoplasms
Semantic Type	Neoplastic Process
Human Phenotype Ontology Id	HP:0000818 HP:0000707 HP:0002664
Human Phenotype Ontology Term	Abnormality of the endocrine system; Abnormality of the nervous system; Neoplasm
Disease Ontology Id	DOID:630 DOID:7 DOID:14566
Disease Ontology Class Name	genetic disease; disease of anatomical entity; disease of cellular proliferation
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
A0A024RAV5	BXGT000013	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b	3845	unreviewed
O00255	BXGT003903	Menin	4221	reviewed
O00522	BXGT003935	Krev interaction trapped protein 1	889	reviewed
O75030	BXGT005096	Microphthalmia-associated transcription factor	4286	reviewed
O75874	BXGT005157	Isocitrate dehydrogenase [NADP] cytoplasmic	3417	reviewed
O95263	BXGT005366	High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B	8622	reviewed
P01106	BXGT005730	Myc proto-oncogene protein	4609	reviewed	Transcription factor
P01112	BXGT005732	GTPase HRas	3265	reviewed	Enzyme modulator
P01116	BXGT005733	GTPase KRas	3845	reviewed	Enzyme modulator
P01189	BXGT005742	Pro-opiomelanocortin	5443	reviewed
P02766	BXGT005953	Transthyretin	7276	reviewed	Transporter
P04271	BXGT006177	Protein S100-B	6285	reviewed	Calcium-binding protein
P04626	BXGT006238	Receptor tyrosine-protein kinase erbB-2	2064	reviewed	Kinase
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P06401	BXGT006436	Progesterone receptor	5241	reviewed	Nuclear receptor
P07101	BXGT006547	Tyrosine 3-monooxygenase	7054	reviewed
P07949	BXGT006703	Proto-oncogene tyrosine-protein kinase receptor Ret	5979	reviewed	Kinase
P08236	BXGT006752	Beta-glucuronidase	2990	reviewed
P09104	BXGT006856	Gamma-enolase	2026	reviewed	Enzyme
P09172	BXGT006865	Dopamine beta-hydroxylase	1621	reviewed
P09455	BXGT006890	Retinol-binding protein 1	5947	reviewed
P09619	BXGT006911	Platelet-derived growth factor receptor beta	5159	reviewed	Kinase
P09874	BXGT006934	Poly [ADP-ribose] polymerase 1	142	reviewed
P0DP23	BXGT007520	Calmodulin-1	808	reviewed
P0DP24	BXGT007521	Calmodulin-2	808	reviewed
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P10721	BXGT007605	Mast/stem cell growth factor receptor Kit	3815	reviewed	Kinase
P11086	BXGT007652	Phenylethanolamine N-methyltransferase	5409	reviewed	Enzyme
P11362	BXGT007693	Fibroblast growth factor receptor 1	2260	reviewed	Kinase
P12004	BXGT007766	Proliferating cell nuclear antigen	5111	reviewed	Nucleic acid binding
P15056	BXGT008075	Serine/threonine-protein kinase B-raf	673	reviewed	Kinase
P15531	BXGT008136	Nucleoside diphosphate kinase A	4830	reviewed	Kinase
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P15941	BXGT008176	Mucin-1	4582	reviewed
P16070	BXGT008186	CD44 antigen	960	reviewed
P16234	BXGT008209	Platelet-derived growth factor receptor alpha	5156	reviewed	Kinase
P16455	BXGT008229	Methylated-DNA--protein-cysteine methyltransferase	4255	reviewed
P17948	BXGT008358	Vascular endothelial growth factor receptor 1	2321	reviewed	Kinase
P19320	BXGT008470	Vascular cell adhesion protein 1	7412	reviewed
P19971	BXGT008537	Thymidine phosphorylase	1890	reviewed	Enzyme
P20132	BXGT008546	L-serine dehydratase/L-threonine deaminase	10993	reviewed	Enzyme
P21359	BXGT008640	Neurofibromin	4763	reviewed	Enzyme modulator
P22607	BXGT008784	Fibroblast growth factor receptor 3	2261	reviewed	Kinase
P23297	BXGT008848	Protein S100-A1	6271	reviewed	Calcium-binding protein
P23443	BXGT008866	Ribosomal protein S6 kinase beta-1	6198	reviewed	Kinase
P23975	BXGT008935	Sodium-dependent noradrenaline transporter	6530	reviewed	Transporter
P24385	BXGT008965	G1/S-specific cyclin-D1	595	reviewed	Enzyme modulator
P25101	BXGT009018	Endothelin-1 receptor	1909	reviewed	G-protein coupled receptor
P30874	BXGT009475	Somatostatin receptor type 2	6752	reviewed	G-protein coupled receptor
P31040	BXGT009503	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial	6389	reviewed	Enzyme
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P40261	BXGT010170	Nicotinamide N-methyltransferase	4837	reviewed	Enzyme
P40337	BXGT010174	von Hippel-Lindau disease tumor suppressor	7428	reviewed	Enzyme
P40926	BXGT010207	Malate dehydrogenase, mitochondrial	4191	reviewed	Enzyme
P46100	BXGT010508	Transcriptional regulator ATRX	546	reviewed
P46527	BXGT010525	Cyclin-dependent kinase inhibitor 1B	1027	reviewed
P48735	BXGT010657	Isocitrate dehydrogenase [NADP], mitochondrial	3418	reviewed
P49841	BXGT010750	Glycogen synthase kinase-3 beta	2932	reviewed	Kinase
P60484	BXGT011307	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	5728	reviewed	Enzyme
P61073	BXGT011352	C-X-C chemokine receptor type 4	7852	reviewed	G-protein coupled receptor
Q00796	BXGT012549	Sorbitol dehydrogenase	6652	reviewed	Enzyme
Q04609	BXGT012768	Glutamate carboxypeptidase 2	2346	reviewed	Enzyme
Q05940	BXGT012846	Synaptic vesicular amine transporter	6571	reviewed	Transporter
Q07075	BXGT012917	Glutamyl aminopeptidase	2028	reviewed	Enzyme
Q07869	BXGT012945	Peroxisome proliferator-activated receptor alpha	5465	reviewed	Nuclear receptor
Q12866	BXGT013273	Tyrosine-protein kinase Mer	10461	reviewed	Kinase
Q12931	BXGT013282	Heat shock protein 75 kDa, mitochondrial	10131	reviewed	Chaperone
Q13085	BXGT013309	Acetyl-CoA carboxylase 1	31	reviewed
Q13315	BXGT013339	Serine-protein kinase ATM	472	reviewed	Kinase
Q13485	BXGT013363	Mothers against decapentaplegic homolog 4	4089	reviewed	Transcription factor
Q16665	BXGT013653	Hypoxia-inducible factor 1-alpha	3091	reviewed	Transcription factor
Q8N0W4	BXGT018492	Neuroligin-4, X-linked	57502	reviewed
Q96KS0	BXGT019688	Egl nine homolog 2	112398	reviewed
Q99814	BXGT019965	Endothelial PAS domain-containing protein 1	2034	reviewed	Transcription factor
Q9GZT9	BXGT020425	Egl nine homolog 1	54583	reviewed
Q9HCR9	BXGT020537	Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A	50940	reviewed
Q9NZQ7	BXGT021281	Programmed cell death 1 ligand 1	29126	reviewed	Receptor
Q9UER7	BXGT021672	Death domain-associated protein 6	1616	reviewed
Q9ULV0	BXGT021763	Unconventional myosin-Vb	4645	reviewed	Cellular structure
Q9Y219	BXGT022206	Protein jagged-2	3714	reviewed
Q9Y6K1	BXGT022331	DNA (cytosine-5)-methyltransferase 3A	1788	reviewed
Q13029	BXGT022688	PR domain zinc finger protein 2	7799	reviewed
Q7Z624	BXGT022792	Calmodulin-lysine N-methyltransferase	79823	reviewed
P15509	BXGT022826	Granulocyte-macrophage colony-stimulating factor receptor subunit alpha	1438	reviewed	Signaling
Q13330	BXGT023103	Metastasis-associated protein MTA1	9112	reviewed	Nucleic acid binding
Q99748	BXGT023217	Neurturin	4902	reviewed	Signaling
P07954	BXGT023939	Fumarate hydratase, mitochondrial	2271	reviewed	Enzyme
O60232	BXGT024169	Protein ZNRD2	10534	reviewed
P0DP25	BXGT024595	Calmodulin-3	808	reviewed
Q9H1K1	BXGT025766	Iron-sulfur cluster assembly enzyme ISCU, mitochondrial	23479	reviewed
P07320	BXGT026150	Gamma-crystallin D	1421	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}