Showing entry for Shigella Infections


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD000823
Disease NameShigella Infections
Disease CUI IdC0013371
MeSH Codes C06   C01  
Disease Class NameDigestive System Diseases; Infections
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7   DOID:0050117  
Disease Ontology Class Namedisease of anatomical entity; disease by infectious agent
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O00401 BXGT003915 Neural Wiskott-Aldrich syndrome protein 8976 reviewed Cellular structure
O60260 BXGT004864 E3 ubiquitin-protein ligase parkin 5071 reviewed Enzyme
O60603 BXGT004887 Toll-like receptor 2 7097 reviewed
O75469 BXGT005128 Nuclear receptor subfamily 1 group I member 2 8856 reviewed Nuclear receptor
P00374 BXGT005520 Dihydrofolate reductase 1719 reviewed Enzyme
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02749 BXGT005941 Beta-2-glycoprotein 1 350 reviewed
P02788 BXGT005963 Lactotransferrin 4057 reviewed Enzyme
P05164 BXGT006333 Myeloperoxidase 4353 reviewed Enzyme
P05231 BXGT006345 Interleukin-6 3569 reviewed
P08236 BXGT006752 Beta-glucuronidase 2990 reviewed
P0DMM9 BXGT007504 Sulfotransferase 1A3 6818 reviewed
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10619 BXGT007589 Lysosomal protective protein 5476 reviewed Enzyme
P11388 BXGT007697 DNA topoisomerase 2-alpha 7153 reviewed
P12694 BXGT007835 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial 593 reviewed
P14635 BXGT008031 G2/mitotic-specific cyclin-B1 891 reviewed Enzyme modulator
P14902 BXGT008065 Indoleamine 2,3-dioxygenase 1 3620 reviewed
P15311 BXGT008106 Ezrin 7430 reviewed Cellular structure
P17643 BXGT008323 5,6-dihydroxyindole-2-carboxylic acid oxidase 7306 reviewed Enzyme
P18206 BXGT008389 Vinculin 7414 reviewed
P21579 BXGT008665 Synaptotagmin-1 6857 reviewed Transporter
P30536 BXGT009435 Translocator protein 706 reviewed
P32455 BXGT009640 Guanylate-binding protein 1 2633 reviewed Enzyme modulator
P34932 BXGT009772 Heat shock 70 kDa protein 4 3308 reviewed
P49662 BXGT010724 Caspase-4 837 reviewed Enzyme
P49913 BXGT010761 Cathelicidin antimicrobial peptide 820 reviewed
P54578 BXGT011056 Ubiquitin carboxyl-terminal hydrolase 14 9097 reviewed Enzyme
P56945 BXGT011206 Breast cancer anti-estrogen resistance protein 1 9564 reviewed
P60022 BXGT011285 Beta-defensin 1 1672 reviewed
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P60953 BXGT011342 Cell division control protein 42 homolog 998 reviewed Enzyme modulator
P61088 BXGT011358 Ubiquitin-conjugating enzyme E2 N 7334 reviewed
P61160 BXGT011365 Actin-related protein 2 10097 reviewed Cellular structure
P61626 BXGT011382 Lysozyme C 4069 reviewed
P63000 BXGT011481 Ras-related C3 botulinum toxin substrate 1 5879 reviewed Enzyme modulator
Q01523 BXGT012594 Defensin-5 1670 reviewed
Q04206 BXGT012754 Transcription factor p65 5970 reviewed Transcription factor
Q05513 BXGT012820 Protein kinase C zeta type 5590 reviewed Kinase
Q13137 BXGT013316 Calcium-binding and coiled-coil domain-containing protein 2 10241 reviewed
Q13501 BXGT013365 Sequestosome-1 8878 reviewed
Q15223 BXGT013551 Nectin-1 5818 reviewed
Q16881 BXGT013688 Thioredoxin reductase 1, cytoplasmic 7296 reviewed Enzyme
Q8NBJ7 BXGT018537 Inactive C-alpha-formylglycine-generating enzyme 2 25870 reviewed
Q9BXR0 BXGT020173 Queuine tRNA-ribosyltransferase catalytic subunit 1 81890 reviewed
Q9H4A3 BXGT020473 Serine/threonine-protein kinase WNK1 65125 reviewed Kinase
Q9HC29 BXGT020526 Nucleotide-binding oligomerization domain-containing protein 2 64127 reviewed Enzyme
Q9UI95 BXGT021714 Mitotic spindle assembly checkpoint protein MAD2B 10459 reviewed
Q9Y239 BXGT022213 Nucleotide-binding oligomerization domain-containing protein 1 10392 reviewed Enzyme
Q9Y6K9 BXGT022333 NF-kappa-B essential modulator 8517 reviewed Kinase
P19875 BXGT023294 C-X-C motif chemokine 2 2920 reviewed Signaling
Q9BQQ3 BXGT024065 Golgi reassembly-stacking protein 1 64689 reviewed
Q9UKU9 BXGT025985 Angiopoietin-related protein 2 23452 reviewed Signaling
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease