Showing entry for Disorder of the optic nerve


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD002117
Disease NameDisorder of the optic nerve
Disease CUI IdC0029132
MeSH Codes C11   C10  
Disease Class NameEye Diseases; Nervous System Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7  
Disease Ontology Class Namedisease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00217 BXGT003898 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial 4728 reviewed Enzyme
O00429 BXGT003919 Dynamin-1-like protein 10059 reviewed Enzyme modulator
O15239 BXGT004139 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 4694 reviewed
O43181 BXGT004576 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial 4724 reviewed
O43676 BXGT004611 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 4709 reviewed
O60313 BXGT004871 Dynamin-like 120 kDa protein, mitochondrial 4976 reviewed Enzyme modulator
O75251 BXGT005107 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial 374291 reviewed
O75306 BXGT005108 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial 4720 reviewed Enzyme
O75380 BXGT005120 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial 4726 reviewed Enzyme
O75489 BXGT005131 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial 4722 reviewed
O96000 BXGT005412 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 4716 reviewed
P00156 BXGT005469 Cytochrome b 4519 reviewed
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P00846 BXGT005674 ATP synthase subunit a 4508 reviewed Transporter
P01130 BXGT005735 Low-density lipoprotein receptor 3949 reviewed
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P03886 BXGT006108 NADH-ubiquinone oxidoreductase chain 1 4535 reviewed Enzyme
P03891 BXGT006110 NADH-ubiquinone oxidoreductase chain 2 4536 reviewed
P03897 BXGT006111 NADH-ubiquinone oxidoreductase chain 3 4537 reviewed
P03901 BXGT006112 NADH-ubiquinone oxidoreductase chain 4L 4539 reviewed Enzyme
P03905 BXGT006113 NADH-ubiquinone oxidoreductase chain 4 4538 reviewed Enzyme
P03915 BXGT006114 NADH-ubiquinone oxidoreductase chain 5 4540 reviewed Enzyme
P03923 BXGT006115 NADH-ubiquinone oxidoreductase chain 6 4541 reviewed
P04179 BXGT006163 Superoxide dismutase [Mn], mitochondrial 6648 reviewed Enzyme
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P06401 BXGT006436 Progesterone receptor 5241 reviewed Nuclear receptor
P09429 BXGT006889 High mobility group protein B1 3146 reviewed Nucleic acid binding
P09488 BXGT006899 Glutathione S-transferase Mu 1 2944 reviewed
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P14210 BXGT007994 Hepatocyte growth factor 3082 reviewed Enzyme
P15121 BXGT008083 Aldo-keto reductase family 1 member B1 231 reviewed Enzyme
P16473 BXGT008234 Thyrotropin receptor 7253 reviewed G-protein coupled receptor
P19404 BXGT008477 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial 4729 reviewed
P21549 BXGT008661 Serine--pyruvate aminotransferase 189 reviewed Enzyme
P24530 BXGT008975 Endothelin receptor type B 1910 reviewed G-protein coupled receptor
P28331 BXGT009252 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial 4719 reviewed Enzyme
P30711 BXGT009460 Glutathione S-transferase theta-1 2952 reviewed
P34932 BXGT009772 Heat shock 70 kDa protein 4 3308 reviewed
P35228 BXGT009800 Nitric oxide synthase, inducible 4843 reviewed
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P45983 BXGT010494 Mitogen-activated protein kinase 8 5599 reviewed Kinase
P49821 BXGT010748 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial 4723 reviewed
P55087 BXGT011105 Aquaporin-4 361 reviewed Ion channel
P56556 BXGT011179 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 4700 reviewed Enzyme
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P60891 BXGT011337 Ribose-phosphate pyrophosphokinase 1 5631 reviewed Kinase
Q01453 BXGT012588 Peripheral myelin protein 22 5376 reviewed Cellular structure
Q15046 BXGT013527 Lysine--tRNA ligase 3735 reviewed Enzyme
Q15077 BXGT013533 P2Y purinoceptor 6 5031 reviewed G-protein coupled receptor
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q16620 BXGT013645 BDNF/NT-3 growth factors receptor 4915 reviewed Kinase
Q16678 BXGT013656 Cytochrome P450 1B1 1545 reviewed Enzyme
Q86Y39 BXGT017632 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 126328 reviewed
Q8N183 BXGT018497 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 91942 reviewed
Q8NBP7 BXGT018541 Proprotein convertase subtilisin/kexin type 9 255738 reviewed Enzyme
Q8WWV3 BXGT019005 Reticulon-4-interacting protein 1, mitochondrial 84816 reviewed
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q99757 BXGT019959 Thioredoxin, mitochondrial 25828 reviewed Enzyme
Q99798 BXGT019962 Aconitate hydratase, mitochondrial 50 reviewed Enzyme
Q99972 BXGT019979 Myocilin 4653 reviewed Cellular structure
Q9BU61 BXGT020131 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 25915 reviewed
Q9NR96 BXGT021181 Toll-like receptor 9 54106 reviewed
Q9NX14 BXGT021242 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial 54539 reviewed Enzyme
Q9P032 BXGT021286 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 29078 reviewed
Q9P0J0 BXGT021287 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 51079 reviewed Enzyme
Q9Y2Q3 BXGT022242 Glutathione S-transferase kappa 1 373156 reviewed
Q9Y375 BXGT022253 Complex I intermediate-associated protein 30, mitochondrial 51103 reviewed
Q9Y6M9 BXGT022336 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 4715 reviewed Enzyme
O95140 BXGT024482 Mitofusin-2 9927 reviewed Enzyme
Q04837 BXGT025484 Single-stranded DNA-binding protein, mitochondrial 6742 reviewed Nucleic acid binding
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease