Showing entry for Wiskott-Aldrich Syndrome


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD003036
Disease NameWiskott-Aldrich Syndrome
Disease CUI IdC0043194
MeSH Codes C16   C20   C15  
Disease Class NameCongenital, Hereditary, and Neonatal Diseases and Abnormalities; Immune System Diseases; Hemic and Lymphatic Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:630  
Disease Ontology Class Namegenetic disease
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00401 BXGT003915 Neural Wiskott-Aldrich syndrome protein 8976 reviewed Cellular structure
O14818 BXGT004103 Proteasome subunit alpha type-7 5688 reviewed
O43772 BXGT004623 Mitochondrial carnitine/acylcarnitine carrier protein 788 reviewed Transporter
O95644 BXGT005389 Nuclear factor of activated T-cells, cytoplasmic 1 4772 reviewed Transcription factor
P00480 BXGT005551 Ornithine carbamoyltransferase, mitochondrial 5009 reviewed
P00558 BXGT005579 Phosphoglycerate kinase 1 5230 reviewed Kinase
P00813 BXGT005667 Adenosine deaminase 100 reviewed Enzyme
P00918 BXGT005690 Carbonic anhydrase 2 760 reviewed
P01589 BXGT005773 Interleukin-2 receptor subunit alpha 3559 reviewed Receptor
P04003 BXGT006124 C4b-binding protein alpha chain 722 reviewed
P05106 BXGT006315 Integrin beta-3 3690 reviewed Receptor
P05231 BXGT006345 Interleukin-6 3569 reviewed
P06734 BXGT006491 Low affinity immunoglobulin epsilon Fc receptor 2208 reviewed Receptor
P07737 BXGT006663 Profilin-1 5216 reviewed
P08246 BXGT006756 Neutrophil elastase 1991 reviewed Enzyme
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P10747 BXGT007609 T-cell-specific surface glycoprotein CD28 940 reviewed
P11413 BXGT007701 Glucose-6-phosphate 1-dehydrogenase 2539 reviewed Enzyme
P15153 BXGT008090 Ras-related C3 botulinum toxin substrate 2 5880 reviewed Enzyme modulator
P16333 BXGT008219 Cytoplasmic protein NCK1 4690 reviewed
P20810 BXGT008602 Calpastatin 831 reviewed
P21333 BXGT008638 Filamin-A 2316 reviewed
P29965 BXGT009388 CD40 ligand 959 reviewed Signaling
P31785 BXGT009577 Cytokine receptor common subunit gamma 3561 reviewed Signaling
P35555 BXGT009845 Fibrillin-1 2200 reviewed Calcium-binding protein
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P40225 BXGT010168 Thrombopoietin 7066 reviewed
P41182 BXGT010231 B-cell lymphoma 6 protein 604 reviewed
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P48061 BXGT010616 Stromal cell-derived factor 1 6387 reviewed
P49917 BXGT010765 DNA ligase 4 3981 reviewed
P56945 BXGT011206 Breast cancer anti-estrogen resistance protein 1 9564 reviewed
P60568 BXGT011315 Interleukin-2 3558 reviewed
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P60953 BXGT011342 Cell division control protein 42 homolog 998 reviewed Enzyme modulator
P61073 BXGT011352 C-X-C chemokine receptor type 4 7852 reviewed G-protein coupled receptor
P61158 BXGT011364 Actin-related protein 3 10096 reviewed Cellular structure
P61160 BXGT011365 Actin-related protein 2 10097 reviewed Cellular structure
Q05397 BXGT012815 Focal adhesion kinase 1 5747 reviewed Kinase
Q06187 BXGT012860 Tyrosine-protein kinase BTK 695 reviewed Kinase
Q07108 BXGT012919 Early activation antigen CD69 969 reviewed
Q13563 BXGT013377 Polycystin-2 5311 reviewed Ion channel
Q8IXH7 BXGT018359 Negative elongation factor C/D 51497 reviewed
Q96AZ6 BXGT019621 Interferon-stimulated gene 20 kDa protein 3669 reviewed
Q96QK1 BXGT019720 Vacuolar protein sorting-associated protein 35 55737 reviewed Transporter
Q99700 BXGT019949 Ataxin-2 6311 reviewed Nucleic acid binding
Q99828 BXGT019967 Calcium and integrin-binding protein 1 10519 reviewed
Q9BZS1 BXGT020203 Forkhead box protein P3 50943 reviewed
Q9Y275 BXGT022223 Tumor necrosis factor ligand superfamily member 13B 10673 reviewed
O60936 BXGT022857 Nucleolar protein 3 8996 reviewed
P31994 BXGT023298 Low affinity immunoglobulin gamma Fc region receptor II-b 2213 reviewed Cell adhesion
Q9UKU9 BXGT025985 Angiopoietin-related protein 2 23452 reviewed Signaling
P19532 BXGT026110 Transcription factor E3 7030 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease