Showing entry for Thyroid Gland Follicular Adenoma


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD003424
Disease NameThyroid Gland Follicular Adenoma
Disease CUI IdC0151468
MeSH Codes C04   C19  
Disease Class NameNeoplasms; Endocrine System Diseases
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id HP:0000818   HP:0002664  
Human Phenotype Ontology TermAbnormality of the endocrine system; Neoplasm
Disease Ontology Id DOID:7   DOID:14566  
Disease Ontology Class Namedisease of anatomical entity; disease of cellular proliferation
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A0A024RAV5 BXGT000013 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b 3845 unreviewed
O00255 BXGT003903 Menin 4221 reviewed
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O14746 BXGT004091 Telomerase reverse transcriptase 7015 reviewed Enzyme
O43791 BXGT004626 Speckle-type POZ protein 8405 reviewed
O60271 BXGT004866 C-Jun-amino-terminal kinase-interacting protein 4 9043 reviewed Enzyme modulator
O60341 BXGT004873 Lysine-specific histone demethylase 1A 23028 reviewed Epigenetic regulator
O60885 BXGT004906 Bromodomain-containing protein 4 23476 reviewed Epigenetic regulator
O95267 BXGT005368 RAS guanyl-releasing protein 1 10125 reviewed Enzyme modulator
O95398 BXGT005378 Rap guanine nucleotide exchange factor 3 10411 reviewed Enzyme modulator
O96017 BXGT005415 Serine/threonine-protein kinase Chk2 11200 reviewed Kinase
P00505 BXGT005560 Aspartate aminotransferase, mitochondrial 2806 reviewed
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P00740 BXGT005634 Coagulation factor IX 2158 reviewed Enzyme
P01111 BXGT005731 GTPase NRas 4893 reviewed Enzyme modulator
P01112 BXGT005732 GTPase HRas 3265 reviewed Enzyme modulator
P01116 BXGT005733 GTPase KRas 3845 reviewed Enzyme modulator
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P03956 BXGT006120 Interstitial collagenase 4312 reviewed Enzyme
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 2064 reviewed Kinase
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P05107 BXGT006316 Integrin beta-2 3689 reviewed Receptor
P05231 BXGT006345 Interleukin-6 3569 reviewed
P06213 BXGT006425 Insulin receptor 3643 reviewed Kinase
P06730 BXGT006487 Eukaryotic translation initiation factor 4E 1977 reviewed Nucleic acid binding
P06753 BXGT006498 Tropomyosin alpha-3 chain 7170 reviewed Cellular structure
P07550 BXGT006636 Beta-2 adrenergic receptor 154 reviewed G-protein coupled receptor
P07949 BXGT006703 Proto-oncogene tyrosine-protein kinase receptor Ret 5979 reviewed Kinase
P08758 BXGT006821 Annexin A5 308 reviewed
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10644 BXGT007597 cAMP-dependent protein kinase type I-alpha regulatory subunit 5573 reviewed
P11473 BXGT007709 Vitamin D3 receptor 7421 reviewed Nuclear receptor
P12004 BXGT007766 Proliferating cell nuclear antigen 5111 reviewed Nucleic acid binding
P12270 BXGT007785 Nucleoprotein TPR 7175 reviewed
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P13640 BXGT007935 Metallothionein-1G 4495 reviewed
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P15056 BXGT008075 Serine/threonine-protein kinase B-raf 673 reviewed Kinase
P15311 BXGT008106 Ezrin 7430 reviewed Cellular structure
P15428 BXGT008121 15-hydroxyprostaglandin dehydrogenase [NAD(+)] 3248 reviewed
P15531 BXGT008136 Nucleoside diphosphate kinase A 4830 reviewed Kinase
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P16070 BXGT008186 CD44 antigen 960 reviewed
P16410 BXGT008224 Cytotoxic T-lymphocyte protein 4 1493 reviewed
P16473 BXGT008234 Thyrotropin receptor 7253 reviewed G-protein coupled receptor
P17931 BXGT008356 Galectin-3 3958 reviewed Signaling
P19793 BXGT008515 Retinoic acid receptor RXR-alpha 6256 reviewed Nuclear receptor
P20339 BXGT008565 Ras-related protein Rab-5A 5868 reviewed
P21579 BXGT008665 Synaptotagmin-1 6857 reviewed Transporter
P21675 BXGT008678 Transcription initiation factor TFIID subunit 1 6872 reviewed Kinase
P21802 BXGT008691 Fibroblast growth factor receptor 2 2263 reviewed Kinase
P22736 BXGT008800 Nuclear receptor subfamily 4 group A member 1 3164 reviewed Nuclear receptor
P24385 BXGT008965 G1/S-specific cyclin-D1 595 reviewed Enzyme modulator
P25024 BXGT009005 C-X-C chemokine receptor type 1 3577 reviewed G-protein coupled receptor
P27487 BXGT009187 Dipeptidyl peptidase 4 1803 reviewed Enzyme
P29033 BXGT009308 Gap junction beta-2 protein 2706 reviewed Cell-cell junction
P30874 BXGT009475 Somatostatin receptor type 2 6752 reviewed G-protein coupled receptor
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35499 BXGT009839 Sodium channel protein type 4 subunit alpha 6329 reviewed Ion channel
P35613 BXGT009856 Basigin 682 reviewed
P35968 BXGT009887 Vascular endothelial growth factor receptor 2 3791 reviewed Kinase
P36888 BXGT009938 Receptor-type tyrosine-protein kinase FLT3 2322 reviewed Kinase
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P38936 BXGT010074 Cyclin-dependent kinase inhibitor 1 1026 reviewed
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P43490 BXGT010395 Nicotinamide phosphoribosyltransferase 10135 reviewed Signaling
P46527 BXGT010525 Cyclin-dependent kinase inhibitor 1B 1027 reviewed
P47736 BXGT010579 Rap1 GTPase-activating protein 1 5909 reviewed Enzyme modulator
P48023 BXGT010604 Tumor necrosis factor ligand superfamily member 6 356 reviewed Signaling
P48061 BXGT010616 Stromal cell-derived factor 1 6387 reviewed
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P50120 BXGT010773 Retinol-binding protein 2 5948 reviewed
P51149 BXGT010835 Ras-related protein Rab-7a 7879 reviewed
P52701 BXGT010943 DNA mismatch repair protein Msh6 2956 reviewed Nucleic acid binding
P53350 BXGT010984 Serine/threonine-protein kinase PLK1 5347 reviewed Kinase
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P61073 BXGT011352 C-X-C chemokine receptor type 4 7852 reviewed G-protein coupled receptor
P63092 BXGT011495 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short 2778 reviewed
P78368 BXGT011840 Casein kinase I isoform gamma-2 1455 reviewed Kinase
P80188 BXGT011882 Neutrophil gelatinase-associated lipocalin 3934 reviewed Enzyme
Q01094 BXGT012568 Transcription factor E2F1 1869 reviewed Nucleic acid binding
Q04206 BXGT012754 Transcription factor p65 5970 reviewed Transcription factor
Q04609 BXGT012768 Glutamate carboxypeptidase 2 2346 reviewed Enzyme
Q05655 BXGT012832 Protein kinase C delta type 5580 reviewed Kinase
Q06710 BXGT012887 Paired box protein Pax-8 7849 reviewed
Q07973 BXGT012952 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 1591 reviewed Enzyme
Q13105 BXGT013311 Zinc finger and BTB domain-containing protein 17 7709 reviewed
Q13822 BXGT013396 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 5168 reviewed Enzyme
Q15274 BXGT013556 Nicotinate-nucleotide pyrophosphorylase [carboxylating] 23475 reviewed
Q16288 BXGT013625 NT-3 growth factor receptor 4916 reviewed Kinase
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q8N339 BXGT018503 Metallothionein-1M 4499 reviewed
Q92731 BXGT019366 Estrogen receptor beta 2100 reviewed Nuclear receptor
Q92793 BXGT019374 CREB-binding protein 1387 reviewed
Q99527 BXGT019930 G-protein coupled estrogen receptor 1 2852 reviewed G-protein coupled receptor
Q9H4A3 BXGT020473 Serine/threonine-protein kinase WNK1 65125 reviewed Kinase
Q9UHV8 BXGT021706 Galactoside-binding soluble lectin 13 29124 reviewed Signaling
Q9UN36 BXGT021780 Protein NDRG2 57447 reviewed Enzyme
Q92911 BXGT022650 Sodium/iodide cotransporter 6528 reviewed Transporter
Q13029 BXGT022688 PR domain zinc finger protein 2 7799 reviewed
P19235 BXGT022895 Erythropoietin receptor 2057 reviewed Receptor
P25054 BXGT022961 Adenomatous polyposis coli protein 324 reviewed
Q9BQQ3 BXGT024065 Golgi reassembly-stacking protein 1 64689 reviewed
P16104 BXGT024571 Histone H2AX 3014 reviewed Nucleic acid binding
Q12888 BXGT024878 TP53-binding protein 1 7158 reviewed Epigenetic regulator
Q13635 BXGT024910 Protein patched homolog 1 5727 reviewed
P00403 BXGT026137 Cytochrome c oxidase subunit 2 4513 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease