Showing entry for Syndactyly of fingers


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD004444
Disease NameSyndactyly of fingers
Disease CUI IdC0221352
MeSH Codes C16   C13   C05  
Disease Class NameCongenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Musculoskeletal Diseases
Semantic TypeCongenital Abnormality
Human Phenotype Ontology Id HP:0040064   HP:0000924  
Human Phenotype Ontology TermAbnormality of limbs; Abnormality of the skeletal system
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O43175 BXGT004575 D-3-phosphoglycerate dehydrogenase 26227 reviewed Enzyme
O60706 BXGT004896 ATP-binding cassette sub-family C member 9 10060 reviewed Transporter
O75369 BXGT005119 Filamin-B 2317 reviewed
O75530 BXGT005135 Polycomb protein EED 8726 reviewed
P07510 BXGT006631 Acetylcholine receptor subunit gamma 1146 reviewed Ion channel
P11362 BXGT007693 Fibroblast growth factor receptor 1 2260 reviewed Kinase
P12830 BXGT007852 Cadherin-1 999 reviewed
P21802 BXGT008691 Fibroblast growth factor receptor 2 2263 reviewed Kinase
P22223 BXGT008744 Cadherin-3 1001 reviewed
P22607 BXGT008784 Fibroblast growth factor receptor 3 2261 reviewed Kinase
P27635 BXGT009194 60S ribosomal protein L10 6134 reviewed Nucleic acid binding
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P38398 BXGT010037 Breast cancer type 1 susceptibility protein 672 reviewed Enzyme
P41227 BXGT010238 N-alpha-acetyltransferase 10 8260 reviewed Enzyme
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P43026 BXGT010351 Growth/differentiation factor 5 8200 reviewed Signaling
P46531 BXGT010526 Neurogenic locus notch homolog protein 1 4851 reviewed
P54132 BXGT011032 Bloom syndrome protein 641 reviewed
P56524 BXGT011176 Histone deacetylase 4 9759 reviewed Epigenetic regulator
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
Q01974 BXGT012628 Tyrosine-protein kinase transmembrane receptor ROR2 4920 reviewed Kinase
Q02127 BXGT012635 Dihydroorotate dehydrogenase (quinone), mitochondrial 1723 reviewed Enzyme
Q06609 BXGT012884 DNA repair protein RAD51 homolog 1 5888 reviewed
Q13627 BXGT013385 Dual specificity tyrosine-phosphorylation-regulated kinase 1A 1859 reviewed Kinase
Q13936 BXGT013404 Voltage-dependent L-type calcium channel subunit alpha-1C 775 reviewed Ion channel
Q14332 BXGT013462 Frizzled-2 2535 reviewed G-protein coupled receptor
Q15022 BXGT013523 Polycomb protein SUZ12 23512 reviewed Nucleic acid binding
Q15223 BXGT013551 Nectin-1 5818 reviewed
Q15465 BXGT013573 Sonic hedgehog protein 6469 reviewed
Q15842 BXGT013607 ATP-sensitive inward rectifier potassium channel 8 3764 reviewed Ion channel
Q15910 BXGT013612 Histone-lysine N-methyltransferase EZH2 2146 reviewed Epigenetic regulator
Q2M1P5 BXGT014129 Kinesin-like protein KIF7 374654 reviewed
Q6PCD5 BXGT016464 E3 ubiquitin-protein ligase RFWD3 55159 reviewed Enzyme
Q86YC2 BXGT017633 Partner and localizer of BRCA2 79728 reviewed
Q8IYD8 BXGT018367 Fanconi anemia group M protein 57697 reviewed Enzyme
Q8TD19 BXGT018804 Serine/threonine-protein kinase Nek9 91754 reviewed Kinase
Q96PY6 BXGT019712 Serine/threonine-protein kinase Nek1 4750 reviewed Kinase
Q99593 BXGT019939 T-box transcription factor TBX5 6910 reviewed Transcription factor
Q99835 BXGT019969 Smoothened homolog 6608 reviewed G-protein coupled receptor
Q9H0F7 BXGT020435 ADP-ribosylation factor-like protein 6 84100 reviewed
Q9NPD8 BXGT021152 Ubiquitin-conjugating enzyme E2 T 29089 reviewed
Q9NPI8 BXGT021161 Fanconi anemia group F protein 2188 reviewed
Q9NW38 BXGT021230 E3 ubiquitin-protein ligase FANCL 55120 reviewed Enzyme
Q9UBM7 BXGT021657 7-dehydrocholesterol reductase 1717 reviewed Enzyme
Q9UI95 BXGT021714 Mitotic spindle assembly checkpoint protein MAD2B 10459 reviewed
Q9Y4D7 BXGT022275 Plexin-D1 23129 reviewed
Q9Y6K9 BXGT022333 NF-kappa-B essential modulator 8517 reviewed Kinase
P25054 BXGT022961 Adenomatous polyposis coli protein 324 reviewed
Q01543 BXGT023137 Friend leukemia integration 1 transcription factor 2313 reviewed Transcription factor
Q96L73 BXGT024676 Histone-lysine N-methyltransferase, H3 lysine-36 specific 64324 reviewed Epigenetic regulator
Q9Y297 BXGT024812 F-box/WD repeat-containing protein 1A 8945 reviewed
Q05086 BXGT025648 Ubiquitin-protein ligase E3A 7337 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease