adisease

Showing entry for Motor symptoms

General Disease Information
BXGD Id	BXGD008599
Disease Name	Motor symptoms
Disease CUI Id	C0426980
MeSH Codes
Disease Class Name
Semantic Type	Sign or Symptom
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O14656	BXGT004080	Torsin-1A	1861	reviewed	Chaperone
O15269	BXGT004145	Serine palmitoyltransferase 1	10558	reviewed	Enzyme
O60259	BXGT004863	Kallikrein-8	11202	reviewed	Enzyme
O75628	BXGT005140	GTP-binding protein REM 1	28954	reviewed
P00441	BXGT005540	Superoxide dismutase [Cu-Zn]	6647	reviewed	Enzyme
P00450	BXGT005544	Ceruloplasmin	1356	reviewed	Enzyme
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P04040	BXGT006132	Catalase	847	reviewed	Enzyme
P04062	BXGT006140	Lysosomal acid glucosylceramidase	2629	reviewed
P04792	BXGT006264	Heat shock protein beta-1	3315	reviewed
P04818	BXGT006269	Thymidylate synthase	7298	reviewed	Enzyme
P07101	BXGT006547	Tyrosine 3-monooxygenase	7054	reviewed
P07737	BXGT006663	Profilin-1	5216	reviewed
P10275	BXGT007552	Androgen receptor	367	reviewed	Nuclear receptor
P10636	BXGT007596	Microtubule-associated protein tau	4137	reviewed
P11166	BXGT007661	Solute carrier family 2, facilitated glucose transporter member 1	6513	reviewed	Transporter
P13637	BXGT007933	Sodium/potassium-transporting ATPase subunit alpha-3	478	reviewed	Transporter
P18074	BXGT008374	General transcription and DNA repair factor IIH helicase subunit XPD	2068	reviewed	Enzyme
P21675	BXGT008678	Transcription initiation factor TFIID subunit 1	6872	reviewed	Kinase
P21980	BXGT008715	Protein-glutamine gamma-glutamyltransferase 2	7052	reviewed	Enzyme
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P27338	BXGT009172	Amine oxidase [flavin-containing] B	4129	reviewed
P29274	BXGT009327	Adenosine receptor A2a	135	reviewed	G-protein coupled receptor
P32004	BXGT009594	Neural cell adhesion molecule L1	3897	reviewed
P34972	BXGT009779	Cannabinoid receptor 2	1269	reviewed	G-protein coupled receptor
P35228	BXGT009800	Nitric oxide synthase, inducible	4843	reviewed
P35462	BXGT009835	D(3) dopamine receptor	1814	reviewed	G-protein coupled receptor
P35858	BXGT009876	Insulin-like growth factor-binding protein complex acid labile subunit	3483	reviewed	Receptor
P37231	BXGT009972	Peroxisome proliferator-activated receptor gamma	5468	reviewed	Nuclear receptor
P37840	BXGT010015	Alpha-synuclein	6622	reviewed	Transporter
P41594	BXGT010266	Metabotropic glutamate receptor 5	2915	reviewed	G-protein coupled receptor
P41597	BXGT010268	C-C chemokine receptor type 2	729230	reviewed
P42858	BXGT010341	Huntingtin	3064	reviewed
P48507	BXGT010636	Glutamate--cysteine ligase regulatory subunit	2730	reviewed	Enzyme
P49768	BXGT010740	Presenilin-1	5663	reviewed	Enzyme
P51813	BXGT010894	Cytoplasmic tyrosine-protein kinase BMX	660	reviewed	Kinase
P53634	BXGT011007	Dipeptidyl peptidase 1	1075	reviewed	Enzyme
P55042	BXGT011100	GTP-binding protein RAD	6236	reviewed
P60484	BXGT011307	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	5728	reviewed	Enzyme
P60880	BXGT011335	Synaptosomal-associated protein 25	6616	reviewed	Transporter
P62258	BXGT011415	14-3-3 protein epsilon	7531	reviewed	Chaperone
P98164	BXGT012230	Low-density lipoprotein receptor-related protein 2	4036	reviewed
Q01064	BXGT012564	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	5153	reviewed
Q01959	BXGT012624	Sodium-dependent dopamine transporter	6531	reviewed	Transporter
Q06787	BXGT012890	Synaptic functional regulator FMR1	2332	reviewed	Nucleic acid binding
Q13148	BXGT013318	TAR DNA-binding protein 43	23435	reviewed
Q13224	BXGT013328	Glutamate receptor ionotropic, NMDA 2B	2904	reviewed	Ion channel
Q13255	BXGT013332	Metabotropic glutamate receptor 1	2911	reviewed	G-protein coupled receptor
Q14833	BXGT013508	Metabotropic glutamate receptor 4	2914	reviewed	G-protein coupled receptor
Q5S007	BXGT015650	Leucine-rich repeat serine/threonine-protein kinase 2	120892	reviewed	Kinase
Q6N021	BXGT016378	Methylcytosine dioxygenase TET2	54790	reviewed
Q9BXM7	BXGT020172	Serine/threonine-protein kinase PINK1, mitochondrial	65018	reviewed	Kinase
Q9BZ23	BXGT020194	Pantothenate kinase 2, mitochondrial	80025	reviewed	Kinase
Q9C098	BXGT020208	Serine/threonine-protein kinase DCLK3	85443	reviewed	Kinase
Q9H0P0	BXGT020439	Cytosolic 5'-nucleotidase 3A	51251	reviewed	Enzyme
Q9Y233	BXGT022210	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	10846	reviewed
P35523	BXGT023831	Chloride channel protein 1	1180	reviewed	Ion channel

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}