Showing entry for Pregnancy associated hypertension


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD010934
Disease NamePregnancy associated hypertension
Disease CUI IdC0852036
MeSH Codes C13   C14  
Disease Class NameFemale Urogenital Diseases and Pregnancy Complications; Cardiovascular Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7  
Disease Ontology Class Namedisease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O60760 BXGT004899 Hematopoietic prostaglandin D synthase 27306 reviewed
O60895 BXGT004907 Receptor activity-modifying protein 2 10266 reviewed Receptor
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] 6647 reviewed Enzyme
P00734 BXGT005630 Prothrombin 2147 reviewed Enzyme
P00747 BXGT005639 Plasminogen 5340 reviewed Enzyme
P00797 BXGT005658 Renin 5972 reviewed Enzyme
P01009 BXGT005714 Alpha-1-antitrypsin 5265 reviewed Enzyme modulator
P01011 BXGT005715 Alpha-1-antichymotrypsin 12 reviewed Enzyme modulator
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P01034 BXGT005721 Cystatin-C 1471 reviewed
P01270 BXGT005746 Parathyroid hormone 5741 reviewed
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01589 BXGT005773 Interleukin-2 receptor subunit alpha 3559 reviewed Receptor
P01909 BXGT005815 HLA class II histocompatibility antigen, DQ alpha 1 chain 3117 reviewed Immune response
P01920 BXGT005817 HLA class II histocompatibility antigen, DQ beta 1 chain 3119 reviewed Immune response
P02647 BXGT005908 Apolipoprotein A-I 335 reviewed
P02656 BXGT005913 Apolipoprotein C-III 345 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02760 BXGT005948 Protein AMBP 259 reviewed
P02765 BXGT005952 Alpha-2-HS-glycoprotein 197 reviewed Enzyme modulator
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P03956 BXGT006120 Interstitial collagenase 4312 reviewed Enzyme
P04054 BXGT006136 Phospholipase A2 5319 reviewed Enzyme
P04278 BXGT006182 Sex hormone-binding globulin 6462 reviewed
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P05164 BXGT006333 Myeloperoxidase 4353 reviewed Enzyme
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05362 BXGT006350 Intercellular adhesion molecule 1 3383 reviewed
P06213 BXGT006425 Insulin receptor 3643 reviewed Kinase
P06744 BXGT006494 Glucose-6-phosphate isomerase 2821 reviewed Enzyme
P06850 BXGT006511 Corticoliberin 1392 reviewed Signaling
P06858 BXGT006515 Lipoprotein lipase 4023 reviewed Enzyme
P06870 BXGT006518 Kallikrein-1 3816 reviewed Enzyme
P07202 BXGT006565 Thyroid peroxidase 7173 reviewed Enzyme
P08069 BXGT006723 Insulin-like growth factor 1 receptor 3480 reviewed Kinase
P08235 BXGT006751 Mineralocorticoid receptor 4306 reviewed Nuclear receptor
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08588 BXGT006795 Beta-1 adrenergic receptor 153 reviewed G-protein coupled receptor
P08684 BXGT006812 Cytochrome P450 3A4 1576 reviewed Enzyme
P08686 BXGT006813 Steroid 21-hydroxylase 1589 reviewed
P09211 BXGT006869 Glutathione S-transferase P 2950 reviewed
P09237 BXGT006874 Matrilysin 4316 reviewed Enzyme
P09382 BXGT006882 Galectin-1 3956 reviewed Signaling
P09601 BXGT006909 Heme oxygenase 1 3162 reviewed
P09917 BXGT006941 Arachidonate 5-lipoxygenase 240 reviewed Enzyme
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10600 BXGT007584 Transforming growth factor beta-3 proprotein 7043 reviewed Signaling
P10646 BXGT007598 Tissue factor pathway inhibitor 7035 reviewed Enzyme modulator
P10828 BXGT007624 Thyroid hormone receptor beta 7068 reviewed Nuclear receptor
P11473 BXGT007709 Vitamin D3 receptor 7421 reviewed Nuclear receptor
P11511 BXGT007717 Aromatase 1588 reviewed Enzyme
P12314 BXGT007798 High affinity immunoglobulin gamma Fc receptor I 2209 reviewed Cell adhesion
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P14060 BXGT007978 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 3283 reviewed Enzyme
P14555 BXGT008020 Phospholipase A2, membrane associated 5320 reviewed Enzyme
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P15090 BXGT008079 Fatty acid-binding protein, adipocyte 2167 reviewed
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P17936 BXGT008357 Insulin-like growth factor-binding protein 3 3486 reviewed Enzyme modulator
P17948 BXGT008358 Vascular endothelial growth factor receptor 1 2321 reviewed Kinase
P18827 BXGT008427 Syndecan-1 6382 reviewed Extracellular structure
P19099 BXGT008456 Cytochrome P450 11B2, mitochondrial 1585 reviewed
P19320 BXGT008470 Vascular cell adhesion protein 1 7412 reviewed
P19429 BXGT008479 Troponin I, cardiac muscle 7137 reviewed Cellular structure
P20815 BXGT008604 Cytochrome P450 3A5 1577 reviewed Enzyme
P24530 BXGT008975 Endothelin receptor type B 1910 reviewed G-protein coupled receptor
P25101 BXGT009018 Endothelin-1 receptor 1909 reviewed G-protein coupled receptor
P27169 BXGT009161 Serum paraoxonase/arylesterase 1 5444 reviewed
P28223 BXGT009239 5-hydroxytryptamine receptor 2A 3356 reviewed G-protein coupled receptor
P28845 BXGT009297 Corticosteroid 11-beta-dehydrogenase isozyme 1 3290 reviewed
P29474 BXGT009352 Nitric oxide synthase, endothelial 4846 reviewed
P30556 BXGT009441 Type-1 angiotensin II receptor 185 reviewed G-protein coupled receptor
P31645 BXGT009558 Sodium-dependent serotonin transporter 6532 reviewed Transporter
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P35228 BXGT009800 Nitric oxide synthase, inducible 4843 reviewed
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35968 BXGT009887 Vascular endothelial growth factor receptor 2 3791 reviewed Kinase
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P41222 BXGT010237 Prostaglandin-H2 D-isomerase 5730 reviewed Enzyme
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P43652 BXGT010405 Afamin 173 reviewed Transporter
P48357 BXGT010627 Leptin receptor 3953 reviewed Signaling
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P49763 BXGT010737 Placenta growth factor 5228 reviewed Signaling
P49767 BXGT010739 Vascular endothelial growth factor C 7424 reviewed Signaling
P50052 BXGT010768 Type-2 angiotensin II receptor 186 reviewed G-protein coupled receptor
P60508 BXGT011309 Syncytin-2 405754 reviewed
P61769 BXGT011383 Beta-2-microglobulin 567 reviewed Immune response
P62937 BXGT011471 Peptidyl-prolyl cis-trans isomerase A 5478 reviewed
P63104 BXGT011499 14-3-3 protein zeta/delta 7534 reviewed Chaperone
P63261 BXGT011512 Actin, cytoplasmic 2 71 reviewed Cellular structure
P78556 BXGT011849 C-C motif chemokine 20 6364 reviewed Signaling
P80365 BXGT011895 Corticosteroid 11-beta-dehydrogenase isozyme 2 3291 reviewed Enzyme
P98160 BXGT012228 Basement membrane-specific heparan sulfate proteoglycan core protein 3339 reviewed Enzyme modulator
Q07869 BXGT012945 Peroxisome proliferator-activated receptor alpha 5465 reviewed Nuclear receptor
Q13219 BXGT013327 Pappalysin-1 5069 reviewed
Q13586 BXGT013380 Stromal interaction molecule 1 6786 reviewed
Q15116 BXGT013539 Programmed cell death protein 1 5133 reviewed
Q15848 BXGT013609 Adiponectin 9370 reviewed
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q16874 BXGT013685 Cytochrome P450 21-hydroxylase 1589 unreviewed
Q5Y7D3 BXGT015912 HLA class II histocompatibility antigen DQ beta chain 3119 unreviewed
Q8N1Q1 BXGT018499 Carbonic anhydrase 13 377677 reviewed
Q92743 BXGT019368 Serine protease HTRA1 5654 reviewed Enzyme
Q96AZ6 BXGT019621 Interferon-stimulated gene 20 kDa protein 3669 reviewed
Q99707 BXGT019952 Methionine synthase 4548 reviewed
Q9BYF1 BXGT020186 Angiotensin-converting enzyme 2 59272 reviewed Enzyme
Q9BZS1 BXGT020203 Forkhead box protein P3 50943 reviewed
Q9NPH2 BXGT021158 Inositol-3-phosphate synthase 1 51477 reviewed
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9UI32 BXGT021711 Glutaminase liver isoform, mitochondrial 27165 reviewed Enzyme
Q9UQF0 BXGT021812 Syncytin-1 30816 reviewed
P00738 BXGT022874 Haptoglobin 3240 reviewed Enzyme
Q8TBZ3 BXGT023141 WD repeat-containing protein 20 91833 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease