adisease

Showing entry for tumor vasculature

General Disease Information
BXGD Id	BXGD013486
Disease Name	tumor vasculature
Disease CUI Id	C1658953
MeSH Codes
Disease Class Name
Semantic Type	Neoplastic Process
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O14746	BXGT004091	Telomerase reverse transcriptase	7015	reviewed	Enzyme
O14757	BXGT004092	Serine/threonine-protein kinase Chk1	1111	reviewed	Kinase
O14763	BXGT004093	Tumor necrosis factor receptor superfamily member 10B	8795	reviewed
O14786	BXGT004099	Neuropilin-1	8829	reviewed
O15123	BXGT004130	Angiopoietin-2	285	reviewed	Signaling
O60674	BXGT004892	Tyrosine-protein kinase JAK2	3717	reviewed	Kinase
O60858	BXGT004903	E3 ubiquitin-protein ligase TRIM13	10206	reviewed
O75365	BXGT005115	Protein tyrosine phosphatase type IVA 3	11156	reviewed
O95150	BXGT005351	Tumor necrosis factor ligand superfamily member 15	9966	reviewed	Signaling
P00338	BXGT005504	L-lactate dehydrogenase A chain	3939	reviewed	Enzyme
P00491	BXGT005555	Purine nucleoside phosphorylase	4860	reviewed	Enzyme
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P00749	BXGT005641	Urokinase-type plasminogen activator	5328	reviewed	Enzyme
P01111	BXGT005731	GTPase NRas	4893	reviewed	Enzyme modulator
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01189	BXGT005742	Pro-opiomelanocortin	5443	reviewed
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01574	BXGT005768	Interferon beta	3456	reviewed
P02750	BXGT005942	Leucine-rich alpha-2-glycoprotein	116844	reviewed
P02751	BXGT005943	Fibronectin	2335	reviewed	Signaling
P02786	BXGT005961	Transferrin receptor protein 1	7037	reviewed	Enzyme
P04083	BXGT006147	Annexin A1	301	reviewed
P04275	BXGT006180	von Willebrand factor	7450	reviewed	Enzyme modulator
P05121	BXGT006320	Plasminogen activator inhibitor 1	5054	reviewed	Enzyme modulator
P05231	BXGT006345	Interleukin-6	3569	reviewed
P05362	BXGT006350	Intercellular adhesion molecule 1	3383	reviewed
P06731	BXGT006488	Carcinoembryonic antigen-related cell adhesion molecule 5	1048	reviewed
P07204	BXGT006567	Thrombomodulin	7056	reviewed
P07288	BXGT006591	Prostate-specific antigen	354	reviewed	Enzyme
P07996	BXGT006710	Thrombospondin-1	7057	reviewed
P08183	BXGT006741	ATP-dependent translocase ABCB1	5243	reviewed	Transporter
P08253	BXGT006757	72 kDa type IV collagenase	4313	reviewed	Enzyme
P08581	BXGT006794	Hepatocyte growth factor receptor	4233	reviewed	Kinase
P08758	BXGT006821	Annexin A5	308	reviewed
P09038	BXGT006851	Fibroblast growth factor 2	2247	reviewed	Signaling
P09619	BXGT006911	Platelet-derived growth factor receptor beta	5159	reviewed	Kinase
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P10644	BXGT007597	cAMP-dependent protein kinase type I-alpha regulatory subunit	5573	reviewed
P11362	BXGT007693	Fibroblast growth factor receptor 1	2260	reviewed	Kinase
P13501	BXGT007917	C-C motif chemokine 5	6352	reviewed	Signaling
P13726	BXGT007950	Tissue factor	2152	reviewed	Receptor
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P15144	BXGT008087	Aminopeptidase N	290	reviewed	Enzyme
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P16109	BXGT008194	P-selectin	6403	reviewed
P16581	BXGT008245	E-selectin	6401	reviewed
P17707	BXGT008331	S-adenosylmethionine decarboxylase proenzyme	262	reviewed	Enzyme
P17948	BXGT008358	Vascular endothelial growth factor receptor 1	2321	reviewed	Kinase
P19320	BXGT008470	Vascular cell adhesion protein 1	7412	reviewed
P20827	BXGT008606	Ephrin-A1	1942	reviewed	Kinase
P22897	BXGT008816	Macrophage mannose receptor 1	4360	reviewed
P23945	BXGT008931	Follicle-stimulating hormone receptor	2492	reviewed	G-protein coupled receptor
P24385	BXGT008965	G1/S-specific cyclin-D1	595	reviewed	Enzyme modulator
P24530	BXGT008975	Endothelin receptor type B	1910	reviewed	G-protein coupled receptor
P25024	BXGT009005	C-X-C chemokine receptor type 1	3577	reviewed	G-protein coupled receptor
P25025	BXGT009006	C-X-C chemokine receptor type 2	3579	reviewed	G-protein coupled receptor
P27707	BXGT009201	Deoxycytidine kinase	1633	reviewed	Kinase
P28482	BXGT009263	Mitogen-activated protein kinase 1	5594	reviewed	Kinase
P29317	BXGT009331	Ephrin type-A receptor 2	1969	reviewed	Kinase
P29323	BXGT009334	Ephrin type-B receptor 2	2048	reviewed	Kinase
P29474	BXGT009352	Nitric oxide synthase, endothelial	4846	reviewed
P30989	BXGT009492	Neurotensin receptor type 1	4923	reviewed	G-protein coupled receptor
P31749	BXGT009574	RAC-alpha serine/threonine-protein kinase	207	reviewed	Kinase
P32004	BXGT009594	Neural cell adhesion molecule L1	3897	reviewed
P32929	BXGT009682	Cystathionine gamma-lyase	1491	reviewed	Enzyme
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P35414	BXGT009829	Apelin receptor	187	reviewed	G-protein coupled receptor
P35968	BXGT009887	Vascular endothelial growth factor receptor 2	3791	reviewed	Kinase
P37023	BXGT009953	Serine/threonine-protein kinase receptor R3	94	reviewed	Kinase
P39060	BXGT010088	Collagen alpha-1(XVIII) chain	80781	reviewed
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P41180	BXGT010230	Extracellular calcium-sensing receptor	846	reviewed	G-protein coupled receptor
P41597	BXGT010268	C-C chemokine receptor type 2	729230	reviewed
P42574	BXGT010317	Caspase-3	836	reviewed	Enzyme
P46531	BXGT010526	Neurogenic locus notch homolog protein 1	4851	reviewed
P48061	BXGT010616	Stromal cell-derived factor 1	6387	reviewed
P49327	BXGT010694	Fatty acid synthase	2194	reviewed	Enzyme
P49765	BXGT010738	Vascular endothelial growth factor B	7423	reviewed	Signaling
P50591	BXGT010814	Tumor necrosis factor ligand superfamily member 10	8743	reviewed	Signaling
P51681	BXGT010878	C-C chemokine receptor type 5	1234	reviewed	G-protein coupled receptor
P58335	BXGT011233	Anthrax toxin receptor 2	118429	reviewed	Receptor
P60568	BXGT011315	Interleukin-2	3558	reviewed
P61073	BXGT011352	C-X-C chemokine receptor type 4	7852	reviewed	G-protein coupled receptor
P78310	BXGT011830	Coxsackievirus and adenovirus receptor	1525	reviewed
P78380	BXGT011841	Oxidized low-density lipoprotein receptor 1	4973	reviewed
Q00987	BXGT012559	E3 ubiquitin-protein ligase Mdm2	4193	reviewed	Nucleic acid binding
Q02750	BXGT012662	Dual specificity mitogen-activated protein kinase kinase 1	5604	reviewed	Kinase
Q02763	BXGT012667	Angiopoietin-1 receptor	7010	reviewed	Kinase
Q03692	BXGT012735	Collagen alpha-1(X) chain	1300	reviewed	Extracellular structure
Q04609	BXGT012768	Glutamate carboxypeptidase 2	2346	reviewed	Enzyme
Q13219	BXGT013327	Pappalysin-1	5069	reviewed
Q14627	BXGT013492	Interleukin-13 receptor subunit alpha-2	3598	reviewed	Signaling
Q14994	BXGT013519	Nuclear receptor subfamily 1 group I member 3	9970	reviewed	Nuclear receptor
Q15125	BXGT013543	3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	10682	reviewed	Enzyme
Q15389	BXGT013564	Angiopoietin-1	284	reviewed	Signaling
Q15392	BXGT013566	Delta(24)-sterol reductase	1718	reviewed	Enzyme
Q15582	BXGT013581	Transforming growth factor-beta-induced protein ig-h3	7045	reviewed	Signaling
Q15831	BXGT013604	Serine/threonine-protein kinase STK11	6794	reviewed	Kinase
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	4780	reviewed	Enzyme
Q16637	BXGT013646	Survival motor neuron protein	6607	reviewed	Epigenetic regulator
Q16665	BXGT013653	Hypoxia-inducible factor 1-alpha	3091	reviewed	Transcription factor
Q16790	BXGT013670	Carbonic anhydrase 9	768	reviewed
Q16875	BXGT013686	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3	5209	reviewed	Kinase
Q86T13	BXGT017603	C-type lectin domain family 14 member A	161198	reviewed
Q9BZR6	BXGT020202	Reticulon-4 receptor	65078	reviewed
Q9BZS1	BXGT020203	Forkhead box protein P3	50943	reviewed
Q9H6X2	BXGT020486	Anthrax toxin receptor 1	84168	reviewed	Receptor
Q9H6Z9	BXGT020488	Egl nine homolog 3	112399	reviewed
Q9HBA0	BXGT020516	Transient receptor potential cation channel subfamily V member 4	59341	reviewed	Ion channel
Q9HC29	BXGT020526	Nucleotide-binding oligomerization domain-containing protein 2	64127	reviewed	Enzyme
Q9NZQ7	BXGT021281	Programmed cell death 1 ligand 1	29126	reviewed	Receptor
Q9UNQ0	BXGT021792	ATP-binding cassette sub-family G member 2	9429	reviewed	Transporter
Q9Y239	BXGT022213	Nucleotide-binding oligomerization domain-containing protein 1	10392	reviewed	Enzyme
Q9Y4D7	BXGT022275	Plexin-D1	23129	reviewed
P19235	BXGT022895	Erythropoietin receptor	2057	reviewed	Receptor
P16284	BXGT022972	Platelet endothelial cell adhesion molecule	5175	reviewed	Cell adhesion
P07954	BXGT023939	Fumarate hydratase, mitochondrial	2271	reviewed	Enzyme
V9HWB9	BXGT026149	L-lactate dehydrogenase	3939	unreviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}