Showing entry for Anthrax toxin receptor 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT020486
Protein NameAnthrax toxin receptor 1
Uniport IdQ9H6X2
GeneANTXR1
Gene Id84168
DomainAnth_Ig; Ant_C; VWA
Pfam PF05586   PF05587   PF00092  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
5. Organismal Systems 5.1 Immune system hsa04621 NOD-like receptor signaling pathway
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0031532 actin cytoskeleton reorganization
Biological Process GO:0001568 blood vessel development
Biological Process GO:1901202 negative regulation of extracellular matrix assembly
Biological Process GO:1905050 positive regulation of metallopeptidase activity
Biological Process GO:0022414 reproductive process
Biological Process GO:0034446 substrate adhesion-dependent cell spreading
Biological Process GO:1901998 toxin transport
molecular function GO:0051015 actin filament binding
molecular function GO:0005518 collagen binding
molecular function GO:0046872 metal ion binding
molecular function GO:0004888 transmembrane signaling receptor activity
cellular component GO:0009986 cell surface
cellular component GO:0010008 endosome membrane
cellular component GO:0009897 external side of plasma membrane
cellular component GO:0031527 filopodium membrane
cellular component GO:0016021 integral component of membrane
cellular component GO:0031258 lamellipodium membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000846 BXGD000015 Agenesis
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0002170 BXGD000105 Alopecia Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002453 BXGD000117 Amenorrhea Pathological Conditions, Signs and Symptoms
C0002895 BXGD000152 Anemia, Sickle Cell Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0003175 BXGD000187 Anthrax disease Infections
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0004565 BXGD000276 Melanoma, B16 Neoplasms
C0005890 BXGD000345 Body Height
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0008297 BXGD000522 Choanal Atresia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0009375 BXGD000602 Colonic Neoplasms Digestive System Diseases; Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0013336 BXGD000815 Dwarfism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C0013390 BXGD000828 Dysmenorrhea Pathological Conditions, Signs and Symptoms
C0014511 BXGD000920 Epithelial cyst Neoplasms
C0017601 BXGD001125 Glaucoma Eye Diseases
C0018916 BXGD001245 Hemangioma Neoplasms
C0019209 BXGD001305 Hepatomegaly Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0020534 BXGD001421 Orbital separation excessive Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0020619 BXGD001447 Hypogonadism Endocrine System Diseases
C0020678 BXGD001463 Hypotrichosis Skin and Connective Tissue Diseases
C0022578 BXGD001557 Keratoconus Eye Diseases
C0025202 BXGD001832 melanoma Neoplasms
C0025990 BXGD001884 Micrognathism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C0027092 BXGD001971 Myopia Eye Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0028738 BXGD002081 Nystagmus Eye Diseases; Nervous System Diseases
C0028960 BXGD002101 Oligospermia Male Urogenital Diseases
C0029124 BXGD002113 Optic Atrophy Eye Diseases; Nervous System Diseases
C0036439 BXGD002615 Scoliosis, unspecified Musculoskeletal Diseases
C0037268 BXGD002675 Skin Abnormalities Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0037293 BXGD002684 Skin tag Pathological Conditions, Signs and Symptoms; Neoplasms; Skin and Connective Tissue Diseases
C0038379 BXGD002752 Strabismus Eye Diseases; Nervous System Diseases
C0040420 BXGD002861 Tonometry
C0040458 BXGD002868 Unerupted tooth Stomatognathic Diseases
C0042373 BXGD002978 Vascular Diseases Cardiovascular Diseases
C0042834 BXGD003004 Vital capacity
C0042974 BXGD003019 von Willebrand Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0085636 BXGD003218 Photophobia Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0086437 BXGD003282 Joint laxity Musculoskeletal Diseases
C0151740 BXGD003468 Intracranial Hypertension Nervous System Diseases
C0153690 BXGD003684 Secondary malignant neoplasm of bone Pathological Conditions, Signs and Symptoms; Neoplasms; Musculoskeletal Diseases
C0162285 BXGD003928 Edema of eyelid Female Urogenital Diseases and Pregnancy Complications; Eye Diseases; Skin and Connective Tissue Diseases; Male Urogenital Diseases; Immune System Diseases; Cardiovascular Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0206733 BXGD004278 Strawberry nevus of skin Neoplasms
C0221354 BXGD004446 Frontal bossing Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0239174 BXGD004969 Late tooth eruption
C0239234 BXGD004974 Low set ears
C0239676 BXGD004989 High forehead
C0241074 BXGD005078 Hyperextensible skin
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0262444 BXGD005244 Abnormality of the dentition Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0264408 BXGD005387 Childhood asthma Respiratory Tract Diseases; Immune System Diseases
C0266013 BXGD005606 Congenital hypoplasia of breast Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0277828 BXGD006480 Late fontanel closure
C0278488 BXGD006515 Carcinoma breast stage IV
C0278701 BXGD006566 Gastric Adenocarcinoma Digestive System Diseases; Neoplasms
C0333516 BXGD006957 Tumor necrosis Pathological Conditions, Signs and Symptoms
C0346429 BXGD007828 Multiple malignancy Neoplasms
C0349588 BXGD007933 Short stature
C0392525 BXGD008052 Nephrolithiasis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0399526 BXGD008251 Class III malocclusion Stomatognathic Diseases
C0406723 BXGD008366 Growth retardation, Alopecia, Pseudoanodontia and Optic atrophy Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Skin and Connective Tissue Diseases; Nervous System Diseases; Stomatognathic Diseases
C0432073 BXGD008719 Defect of skull ossification
C0432355 BXGD008780 Hypoplasia of nipple
C0456070 BXGD008863 Growth delay
C0489786 BXGD009018 Height
C0541764 BXGD009259 Delayed bone age
C0581342 BXGD009560 Redundant skin Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0860580 BXGD011232 Medullary carcinoma of breast
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1306503 BXGD012363 Congenital exomphalos Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C1384666 BXGD012948 hearing impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C1519666 BXGD013240 Tumor-Associated Vasculature
C1519670 BXGD013241 Tumor Angiogenesis Pathological Conditions, Signs and Symptoms
C1519680 BXGD013244 Tumor Immunity Pathological Conditions, Signs and Symptoms
C1658953 BXGD013486 tumor vasculature
C1704436 BXGD013564 Peripheral Arterial Diseases Cardiovascular Diseases
C1832446 BXGD013844 Sparse eyebrow
C1832661 BXGD013866 ANOPHTHALMIA AND PULMONARY HYPOPLASIA Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Respiratory Tract Diseases
C1834405 BXGD013970 Nail dysplasia Pathological Conditions, Signs and Symptoms
C1836542 BXGD014129 Depressed nasal bridge
C1836735 BXGD014155 hypopigmented skin patch Skin and Connective Tissue Diseases
C1837404 BXGD014229 High, narrow palate
C1839326 BXGD014367 Abnormal form of the vertebral bodies
C1839739 BXGD014400 Thick lower lip vermilion
C1840077 BXGD014434 Anteverted nostril
C1843300 BXGD014572 Sparse eyelashes
C1844809 BXGD014677 Thick nasal alae
C1849089 BXGD015004 Broad forehead
C1853242 BXGD015322 Midface retrusion
C1853246 BXGD015323 Eversion of lower lip
C1855285 BXGD015483 Protruding ear
C1856542 BXGD015615 Prominent scalp veins
C1857656 BXGD015731 Prematurely aged appearance
C1858033 BXGD015762 Asymmetry of the thorax
C1861869 BXGD016088 Underdeveloped supraorbital ridges
C1865014 BXGD016282 Long philtrum
C1865186 BXGD016296 Bell-shaped thorax
C1865871 BXGD016349 HEMANGIOMA, CAPILLARY INFANTILE Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms
C1866134 BXGD016378 Wide anterior fontanel
C1963184 BXGD016688 Nystagmus, CTCAE 3.0
C1969372 BXGD016775 Tubulointerstitial fibrosis
C2211694 BXGD016941 medullary carcinoma with lymphoid stroma of breast
C2919142 BXGD017867 Short Stature, CTCAE
C3279947 BXGD018789 NAIL DISORDER, NONSYNDROMIC CONGENITAL, 9
C3539878 BXGD019087 Triple Negative Breast Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C3553764 BXGD019187 Joint hyperflexibility
C3665347 BXGD019279 Visual Impairment Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C3714514 BXGD019409 Infection Infections
C4020847 BXGD020486 Abnormality of pelvic girdle bone morphology
C4021768 BXGD020766 Abnormality of metabolism/homeostasis
C4021792 BXGD020783 Abnormality of the clavicle
C4021815 BXGD020801 Abnormal palate morphology
C4022001 BXGD020863 Abnormality of the cerebral vasculature
C4025272 BXGD021615 Peripheral arterial stenosis
C4025718 BXGD021753 Early balding
C4025814 BXGD021806 Abnormality of the metaphysis
C4282407 BXGD022423 Sparse and thin eyebrow
C4317089 BXGD022721 Infantile hemangioma Neoplasms; Cardiovascular Diseases
C4321477 BXGD022752 Sickle Cell-SS Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C4554036 BXGD023557 Nystagmus, CTCAE 5.0
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
C4722518 BXGD023806 Triple-Negative Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
BXGC0049447 acetate 59.01
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein