Showing entry for Mitochondrial abnormalities


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD020474
Disease NameMitochondrial abnormalities
Disease CUI IdC4020732
MeSH Codes   
Disease Class Name
Semantic TypeAnatomical Abnormality
Human Phenotype Ontology Id HP:0001939   HP:0025354  
Human Phenotype Ontology TermAbnormality of metabolism/homeostasis; Abnormal cellular phenotype
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O15553 BXGT004181 Pyrin 4210 reviewed
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] 6647 reviewed Enzyme
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04792 BXGT006264 Heat shock protein beta-1 3315 reviewed
P04839 BXGT006273 Cytochrome b-245 heavy chain 1536 reviewed Ion channel
P05067 BXGT006306 Amyloid-beta precursor protein 351 reviewed Enzyme modulator
P07741 BXGT006666 Adenine phosphoribosyltransferase 353 reviewed
P08174 BXGT006739 Complement decay-accelerating factor 1604 reviewed
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P20132 BXGT008546 L-serine dehydratase/L-threonine deaminase 10993 reviewed Enzyme
P20807 BXGT008601 Calpain-3 825 reviewed Enzyme
P29474 BXGT009352 Nitric oxide synthase, endothelial 4846 reviewed
P36969 BXGT009949 Phospholipid hydroperoxide glutathione peroxidase 2879 reviewed Enzyme
P37840 BXGT010015 Alpha-synuclein 6622 reviewed Transporter
P42345 BXGT010304 Serine/threonine-protein kinase mTOR 2475 reviewed Kinase
P45983 BXGT010494 Mitogen-activated protein kinase 8 5599 reviewed Kinase
P49768 BXGT010740 Presenilin-1 5663 reviewed Enzyme
P54098 BXGT011030 DNA polymerase subunit gamma-1 5428 reviewed Enzyme
P55072 BXGT011103 Transitional endoplasmic reticulum ATPase 7415 reviewed
Q00796 BXGT012549 Sorbitol dehydrogenase 6652 reviewed Enzyme
Q01453 BXGT012588 Peripheral myelin protein 22 5376 reviewed Cellular structure
Q06787 BXGT012890 Synaptic functional regulator FMR1 2332 reviewed Nucleic acid binding
Q13148 BXGT013318 TAR DNA-binding protein 43 23435 reviewed
Q13164 BXGT013322 Mitogen-activated protein kinase 7 5598 reviewed Kinase
Q13315 BXGT013339 Serine-protein kinase ATM 472 reviewed Kinase
Q13501 BXGT013365 Sequestosome-1 8878 reviewed
Q15149 BXGT013547 Plectin 5339 reviewed Cellular structure
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q16654 BXGT013650 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial 5166 reviewed Kinase
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q5S007 BXGT015650 Leucine-rich repeat serine/threonine-protein kinase 2 120892 reviewed Kinase
Q92793 BXGT019374 CREB-binding protein 1387 reviewed
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q99623 BXGT019941 Prohibitin-2 11331 reviewed
Q9BXM7 BXGT020172 Serine/threonine-protein kinase PINK1, mitochondrial 65018 reviewed Kinase
Q9BY32 BXGT020179 Inosine triphosphate pyrophosphatase 3704 reviewed Enzyme
Q9NTG7 BXGT021211 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 23410 reviewed Epigenetic regulator
Q9UM47 BXGT021772 Neurogenic locus notch homolog protein 3 4854 reviewed
P09622 BXGT023116 Dihydrolipoyl dehydrogenase, mitochondrial 1738 reviewed Enzyme
P07954 BXGT023939 Fumarate hydratase, mitochondrial 2271 reviewed Enzyme
O95140 BXGT024482 Mitofusin-2 9927 reviewed Enzyme
Q9Y4W6 BXGT025025 AFG3-like protein 2 10939 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease